Results 181 to 190 of about 53,245 (286)

Ketamine's rapid antidepressant effects are mediated by Ca2+-permeable AMPA receptors. [PDF]

open access: yesElife, 2023
Zaytseva A   +7 more
europepmc   +1 more source

Topiramate Enhances GABAergic Tone to Orexigenic Neuropeptide Y/Agouti‐Related Peptide (NPY/AgRP) Neurons

open access: yesObesity, Volume 34, Issue 1, Page 175-187, January 2026.
ABSTRACT Objective Topiramate is a medication used off‐label, or in combination with phentermine, for the management of obesity. However, its mechanism of action remains elusive. As many obesity medications target the brain, we aimed to determine if topiramate influences the activity of hypothalamic melanocortin neurons known to regulate energy balance.
Moein Minbashi Moeini   +4 more
wiley   +1 more source

Ubiquitination of the GluA1 Subunit of AMPA Receptors Is Required for Synaptic Plasticity, Memory, and Cognitive Flexibility. [PDF]

open access: yesJ Neurosci, 2023
Guntupalli S   +11 more
europepmc   +1 more source

Refractory Peripheral Pulmonary Stenosis and Severe Pulmonary Arterial Hypertension Associated With a De Novo Loss‐of‐Function Variant in FGD5

open access: yesPulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT We report a novel genetic variant in a patient with treatment‐resistant peripheral pulmonary artery stenosis (PPS) and progressive pulmonary arterial hypertension (PAH). A premature infant was diagnosed with bilateral PPS requiring multiple surgical reconstructions and interventional procedures with refractory proximal stenoses.
Lea C. Steffes   +3 more
wiley   +1 more source

Gating and noelin clustering of native Ca<sup>2+</sup>-permeable AMPA receptors. [PDF]

open access: yesNature
Fang C   +5 more
europepmc   +1 more source

5-Nitroisoxazoles in SNAr Reactions: A Novel Chemo- and Regioselective Approach to Isoxazole-Based Bivalent Ligands of AMPA Receptors. [PDF]

open access: yesInt J Mol Sci, 2023
Vasilenko DA   +9 more
europepmc   +1 more source

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