Results 11 to 20 of about 2,326,770 (324)

AMPA receptors and their minions: auxiliary proteins in AMPA receptor trafficking [PDF]

open access: yesCellular and Molecular Life Sciences, 2019
To correctly transfer information, neuronal networks need to continuously adjust their synaptic strength to extrinsic stimuli. This ability, termed synaptic plasticity, is at the heart of their function and is, thus, tightly regulated.
Diane Bissen, F. Foss, A. Acker-Palmer
semanticscholar   +5 more sources

Clathrin-Independent Trafficking of AMPA Receptors [PDF]

open access: yesThe Journal of Neuroscience, 2015
Membrane trafficking of AMPA receptors (AMPARs) is critical for neuronal function and plasticity. Although rapid forms of AMPAR internalization during long-term depression (LTD) require clathrin and dynamin, the mechanisms governing constitutive AMPAR ...
O. Glebov   +3 more
semanticscholar   +5 more sources

Regulation of AMPA receptors in spinal nociception [PDF]

open access: yesMolecular Pain, 2010
The functional properties of α-amino-3-hydroxy-5-methy-4-isoxazole propionate (AMPA) receptors in different brain regions, such as hippocampus and cerebellum, have been well studied in vitro and in vivo. The AMPA receptors present a unique characteristic
Lin Qing   +5 more
doaj   +3 more sources

Stargazin Modulation of AMPA Receptors [PDF]

open access: yesCell Reports, 2016
Fast excitatory synaptic signaling in the mammalian brain is mediated by AMPA-type ionotropic glutamate receptors. In neurons, AMPA receptors co-assemble with auxiliary proteins, such as stargazin, which can markedly alter receptor trafficking and gating.
Shaikh, Sana A.   +7 more
openaire   +5 more sources

Fear Memory Retrieval Is Associated With a Reduction in AMPA Receptor Density at Thalamic to Amygdala Intercalated Cell Synapses

open access: yesFrontiers in Synaptic Neuroscience, 2021
The amygdala plays a crucial role in attaching emotional significance to environmental cues. Its intercalated cell masses (ITC) are tight clusters of GABAergic neurons, which are distributed around the basolateral amygdala complex.
Anna Seewald   +6 more
doaj   +1 more source

Regulation of AMPA Receptors by Phosphorylation [PDF]

open access: yesNeurochemical Research, 2000
The AMPA receptors for glutamate are oligomeric structures that mediate fast excitatory responses in the central nervous system. Phosphorylation of AMPA receptors is an important mechanism for short-term modulation of their function, and is thought to play an important role in synaptic plasticity in different brain regions.
Carvalho, Ana Luísa   +2 more
openaire   +4 more sources

Auxiliary Subunits Control Function and Subcellular Distribution of AMPA Receptor Complexes in NG2 Glia of the Developing Hippocampus

open access: yesFrontiers in Cellular Neuroscience, 2021
Synaptic and axonal glutamatergic signaling to NG2 glia in white matter is critical for the cells’ differentiation and activity dependent myelination. However, in gray matter the impact of neuron-to-NG2 glia signaling is still elusive, because most of ...
Stefan Hardt   +6 more
doaj   +1 more source

Sequential Activation of AMPA Receptors and Glial Cells in a Pain Model of Lumbar Spine Disc Herniation [PDF]

open access: yesAnnals of Rehabilitation Medicine, 2020
Objective To investigate the glial cell and AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor activity after surgery for disc herniation pain model.
Dong Gyu Kwak, Dong Gyu Lee
doaj   +1 more source

Distinct neurexin-cerebellin complexes control AMPA- and NMDA-receptor responses in a circuit-dependent manner

open access: yeseLife, 2022
At CA1→subiculum synapses, alternatively spliced neurexin-1 (Nrxn1SS4+) and neurexin-3 (Nrxn3SS4+) enhance NMDA-receptors and suppress AMPA-receptors, respectively, without affecting synapse formation.
Jinye Dai   +3 more
doaj   +1 more source

SAD-B modulates epileptic seizure by regulating AMPA receptors in patients with temporal lobe epilepsy and in the PTZ-induced epileptic model [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2020
α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are the predominant mediators of glutamate-induced excitatory neurotransmission.
Rong Li   +5 more
doaj   +1 more source

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