Results 21 to 30 of about 593,248 (240)
Frontiers in Synaptic Neuroscience, 2021 The amygdala plays a crucial role in attaching emotional significance to environmental cues. Its intercalated cell masses (ITC) are tight clusters of GABAergic neurons, which are distributed around the basolateral amygdala complex.
Anna Seewald +6 more
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Frontiers in Cellular Neuroscience, 2021 Synaptic and axonal glutamatergic signaling to NG2 glia in white matter is critical for the cells’ differentiation and activity dependent myelination. However, in gray matter the impact of neuron-to-NG2 glia signaling is still elusive, because most of ...
Stefan Hardt +6 more
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AMPA receptors: Role in brain injury [PDF]
, 2003 Glutamate can be considered a 'Jekyll and Hyde' molecule that serves an essential role as neurotransmitter whilst having potentially damaging, neurotoxic effects.
Fowler, Jill H
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Testing of the therapeutic efficacy and safety of AMPA receptor RNA aptamers in an ALS mouse model
Life Science Alliance, 2022 RNA aptamers designed to block AMPA receptors effectively reduce progression of motor dysfunction, improve TDP-43 pathology, and prevent death of motor neurons in AR2 mice, a mouse model of sporadic ALS, without adverse effects.
Megumi Akamatsu +7 more
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SAD-B modulates epileptic seizure by regulating AMPA receptors in patients with temporal lobe epilepsy and in the PTZ-induced epileptic model [PDF]
Brazilian Journal of Medical and Biological Research, 2020 α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are the predominant mediators of glutamate-induced excitatory neurotransmission.
Rong Li +5 more
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eLife, 2022 At CA1→subiculum synapses, alternatively spliced neurexin-1 (Nrxn1SS4+) and neurexin-3 (Nrxn3SS4+) enhance NMDA-receptors and suppress AMPA-receptors, respectively, without affecting synapse formation.
Jinye Dai +3 more
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Molecular Brain, 2021 Reconsolidation has been considered a process in which a consolidated memory is turned into a labile stage. Within the reconsolidation window, the labile memory can be either erased or strengthened.
Boren Lin +9 more
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Sequential Activation of AMPA Receptors and Glial Cells in a Pain Model of Lumbar Spine Disc Herniation [PDF]
Annals of Rehabilitation Medicine, 2020 Objective To investigate the glial cell and AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor activity after surgery for disc herniation pain model.
Dong Gyu Kwak, Dong Gyu Lee
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Potentiation of glycine-gated NR1/NR3A NMDA receptors relieves Ca2+-dependent outward rectification [PDF]
, 2010 Glycine has diverse functions within the mammalian central nervous system. It inhibits postsynaptic neurons via strychnine-sensitive glycine receptors (GlyRs) and enhances neuronal excitation through co-activation of N-methyl-D-aspartate (NMDA) receptors.
Betz, H. +11 more
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AMPA Receptor-Mediated Ca2+ Transients in Mouse Olfactory Ensheathing Cells
Frontiers in Cellular Neuroscience, 2019 Ca2+ signaling in glial cells is primarily triggered by metabotropic pathways and the subsequent Ca2+ release from internal Ca2+ stores. However, there is upcoming evidence that various ion channels might also initiate Ca2+ rises in glial cells by Ca2 ...
Antonia Beiersdorfer, Christian Lohr
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