Results 11 to 20 of about 1,296 (182)
Treatment of Cardiovascular Dysfunction with PDE3-Inhibitors in Moderate and Severe Hypothermia—Effects on Cellular Elimination of Cyclic Adenosine Monophosphate and Cyclic Guanosine Monophosphate [PDF]
Frontiers in Physiology, 2022 Introduction: Rewarming from accidental hypothermia is often complicated by hypothermia-induced cardiovascular dysfunction, which could lead to shock. Current guidelines do not recommend any pharmacological treatment at core temperatures below 30°C, due ...
Adrina Kalasho Kuzmiszyn +13 more
doaj +2 more sources
The Pyruvate Dehydrogenase Complex in Sepsis: Metabolic Regulation and Targeted Therapy [PDF]
Frontiers in Nutrition, 2021 Anaerobic glycolysis is the process by which glucose is broken down into pyruvate and lactate and is the primary metabolic pathway in sepsis. The pyruvate dehydrogenase complex (PDHC) is a multienzyme complex that serves as a critical hub in energy ...
Zhenhua Zeng +6 more
doaj +2 more sources
Cardiac and vascular effects of diltiazem, dobutamine and amrinone, drugs used after myocardial revascularization [PDF]
Brazilian Journal of Medical and Biological Research, 2004 Hemodynamic care during postoperative management of myocardial revascularization should include vasorelaxing drugs to insure adequate graft and coronary flow, and stimulation of stroke volume to maintain vascular perfusion pressure. We tested the cardiac
A. Gómez-Alvis +8 more
doaj +2 more sources
Papaverine effect on superficial vein in thumb replantation procedure: A case study. [PDF]
Clin Case RepKey Clinical Message Topical papaverine is an effective vasodilator that can be used for dilating small veins to accept venous couplers for thumb replantation. This technique corrects size mismatches for successful venous anastomosis and minimizes postoperative complications.
AlSheryani M, AlDhamin A.
europepmc +2 more sources
Myocardial oxygen consumption, myocardial efficiency, and mechanical efficiency: A review across pathologic and physiologic states. [PDF]
Physiol RepAbstract Myocardial work and oxygen consumption (MVO2) are tightly coupled. The patient's physiological state, presence of disease, heart rate, and microvascular control of oxygen delivery all combine to maintain this relationship. The myocardial efficiency (MyoEff) of the heart is determined by the ratio of stroke‐work (SW) divided by MVO2, whereas ...
Pierson JA +3 more
europepmc +2 more sources
Acta Anaesthesiologica Scandinavica, Volume 67, Issue 6, Page 738-745, July 2023., 2023 Abstract Background Acute kidney injury (AKI) and renal dysfunction after heart transplantation are common and serious complications. Atrial natriuretic peptide (ANP) has been shown to increase glomerular filtration rate (GFR) and exert renoprotective effects when used for the prevention/treatment of AKI in cardiac surgery.
Maria Tholén +5 more
wiley +1 more source
Inflammatory mechanisms and intervention strategies for sepsis‐induced myocardial dysfunction
Immunity, Inflammation and Disease, Volume 11, Issue 5, May 2023., 2023 The interaction of inflammatory environment promotes the occurrence and development of myocardial injury induced by sepsis. Abstract Sepsis‐induced myocardial dysfunction (SIMD) is the leading cause of death in patients with sepsis in the intensive care units.
Yuxin Nong, Xuebiao Wei, Danqing Yu
wiley +1 more source
Properties and synthesis of milrinone [PDF]
Hemijska Industrija, 2013 Milrinone, 1,6-dihydro-2-methyl-6-oxo-[3,4’-bipyridine]-5-carbonitrile, is a positive inotropic cardiotonic agent with vasodilator properties that acts as selective phosphodiesterase 3 inhibitor in cardiac and vascular smooth muscle.
Mirković Jelena M. +2 more
doaj +1 more source
International consensus statement on allergy and rhinology: Allergic rhinitis – 2023
International Forum of Allergy &Rhinology, Volume 13, Issue 4, Page 293-859, April 2023., 2023 Abstract Background In the 5 years that have passed since the publication of the 2018 International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis 2018), the literature has expanded substantially. The ICAR‐Allergic Rhinitis 2023 update presents 144 individual topics on allergic rhinitis (AR), expanded by over 40
Sarah K. Wise +126 more
wiley +1 more source
ESC Heart Failure, Volume 9, Issue 4, Page 2272-2278, August 2022., 2022 Abstract Aims Venoarterial extracorporeal membrane oxygenation (VA‐ECMO) is increasingly being used to support patients in cardiogenic shock (CS). Early determination of disposition is paramount, as longer durations of support have been associated with worse outcomes.
Ravi Vuthoori +11 more
wiley +1 more source