Results 31 to 40 of about 101,866 (266)

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti‐Inflammatory Response Syndromes by Targeting PF4+ Macrophages in Acute Pancreatitis

Advanced Science, EarlyView.
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu, Guanqun Li, Dongxu Lu, Haoran Ding, Tianqi Lu, Yuhang Sui, Can Zhang, Yu Xie, Rui Kong, Hua Chen, Xuewei Bai, Hongtao Tan, Dongbo Xue, Xianzhi Meng, Le Li, Bei Sun   +15 more
wiley   +1 more source

PancDS in Real‐World Practice: A Prospective Multicenter Validation of a Clinical Decision‐Support System Bridging Experience Gaps in Pancreatic Lesion Diagnosis

Advanced Science, EarlyView.
A biomimetic artificial intelligence system, PancDS, has been developed to distinguish pancreatic ductal adenocarcinoma from mass‐forming pancreatitis by adaptively integrating clinical data, radiomics, and deep learning features. Validated across multicenter, reader‐study, and prospective settings, PancDS improves diagnostic accuracy, particularly for
Zhibo Wang, Weinuo Qu, Wenwen Cai, Chuhuai Wang, Chenxi Lyu, Qingguo Xie, Qian Chu, Yaqi Shen, Peng Xiao, Feng Li, Qingpeng Zhang, Jiali Li, Jeong Min Lee, Zhen Li   +13 more
wiley   +1 more source

Combined Enzymatic Action of Pseudomonas psedoalcaligenes Protease and Stutzerimonas xanthomarina Amylase in Textile Blood Stain Removal

Journal of Pure and Applied Microbiology
Blood is a body fluid. When it contacts oxygen, it can clot, forming a dark solid substance. In accidents involving wounds, blood is released and can stain clothing when absorbed by fabrics.
A. Linsha Mali, Biljo V. Joseph
doaj   +1 more source

The Amylases of Insects [PDF]

International Journal of Insect Science, 2018
Alpha-amylases are major digestive enzymes that act in the first step of maltopolysaccharide digestion. In insects, these enzymes have long been studied for applied as well as purely scientific purposes. In many species, amylases are produced by multiple gene copies. Rare species are devoid of Amy gene.
openaire   +3 more sources

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

Isolation and Characterization of Low-Temperature and High-Salinity Amylase from Halomonas sp. KS41843

Fermentation
The polar regions harbor uniquely diverse organisms adapted to low temperatures. Strains obtained from these regions are likely to produce enzymes that are industrially useful at low temperatures. In this study, a Halomonas sp.
Jin A Kim, Min Ju Kim, Joung Han Yim, Il-Chan Kim, Jae-Sung Rhee, Se Jong Han   +5 more
doaj   +1 more source

Discriminator‐Guided Inverse Folding for Multi‐Property Protein Design

Advanced Science, EarlyView.
Discriminator‐Guided Inverse Folding (DGIF) integrates multiple property predictors trained from single‐property datasets to guide protein sequence generation from a backbone structure. DGIF enables simultaneous improvement of thermostability and solubility without requiring multi‐property annotated datasets and generates designs that move toward the ...
Yuchuan Zheng, Chuyi Liu, Zhaoming Liu, Mao Su, Chenyu Tang, Xiang Zheng, Hao Zhang, Jingyuan Li   +7 more
wiley   +1 more source

A Comprehensive Study on the Alterations in Liver Enzyme and Pancreatic Enzyme Levels among Patients with Chronic Kidney Disease

Biomedical and Biotechnology Research Journal
Background: Chronic kidney disease (CKD) is a growing global health concern, and the occurrence of liver and pancreatic diseases as comorbid conditions in this patient population is very common.
P. PeddaReddemma, C. K. Vijayasamundeeswari, P. Parvathy, P. Pavani, P. Lavanya   +4 more
doaj   +1 more source

Bridging Performance and Fate: A Framework for Sustainable, Composite‐Based Flexible Electronic Systems

Advanced Electronic Materials, EarlyView.
Composite‐based flexible electronics integrate biodegradable polymers, conductive networks, and multilayer device architectures to balance electrical performance, mechanical durability, and controlled degradation. Interfacial engineering and encapsulation regulate transport stability and operational lifetime, while programmed disassembly enables ...
Sayam, Sangho Cho
wiley   +1 more source

Dependency of Glucose Homeostasis on Pancreatic Enzymes with Special Reference to Amylase; Study on Healthy and Exocrine Pancreatic Insufficient Pigs

Biomolecules
We aimed to highlight the roles of the pancreatic enzymes, with special reference to amylase, on glucose homeostasis in healthy pigs and in pigs with exocrine pancreatic insufficiency (EPI).
Piotr Wychowański, Stefan G. Pierzynowski, Kamil Zaworski, Robert Gallotto, Dominika Szkopek, Jarosław Woliński, Janine Donaldson, Tomasz Jacek, Kateryna Pierzynowska   +8 more
doaj   +1 more source