Results 131 to 140 of about 85,510 (321)

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. [PDF]

, 1993
D. E. Schmechel, Ann M. Saunders, Warren J. Strittmatter, Barbara J. Crain, Christine M. Hulette, Sun Hyung Joo, Margaret A. Pericak‐Vance, Dmitry Goldgaber, Allen D. Roses   +8 more
openalex   +1 more source

Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging. [PDF]

, 1994
Jan Näslund, Angelika Schierhorn, Ulf Hellman, Lars Lannfelt, A.D. Roses, Lars O. Tjernberg, Jerzy Silberring, Sam Gandy, Bengt Winblad, Paul Greengard   +9 more
openalex   +1 more source

Amyloid Beta Peptides Lead to Mast Cell Activation in a Novel 3D Hydrogel Model. [PDF]

Int J Mol Sci, 2023
Liu J, Liu S, Zeng L, Tsilioni I.
europepmc   +1 more source

Beta-amyloid oligomers: recent developments

Biomolecular Concepts, 2011
Recent studies point to a critical role of soluble β-amyloid oligomers in the pathogenesis of one of the most common neurodegenerative diseases, Alzheimer's disease (AD).
Borutaite Vilmante, Morkuniene Ramune, Valincius Gintaras   +2 more
doaj   +1 more source

A Single‐Molecule Liposome Assay for Membrane Permeabilisation

Angewandte Chemie International Edition, Accepted Article.
Cell membrane disruption is associated with numerous diseases and underlies the activity of various antimicrobial agents. The rapid screening of compounds capable of disrupting or permeabilising biological membranes is essential to the search for new therapeutic drugs.
Krzysztof Marek Bąk, Daniel Edwards, Dylan George, Bhanu Singh, Ryan Ferguson, Tianxiao Zhao, Kristin Piché, Ariel Louwrier, Scott Lee Cockroft, Mathew Horrocks   +9 more
wiley   +1 more source

Amyloid-Beta Peptides Trigger Premature Functional and Gene Expression Alterations in Human-Induced Neurons. [PDF]

Biomedicines, 2023
Melo de Farias AR, Pelletier A, Iohan LCC, Saha O, Bonnefond A, Amouyel P, Delahaye F, Lambert JC, Costa MR.   +8 more
europepmc   +1 more source

A Metalloproteinase Cocktail from the Venom of Protobothrops flavoviridis Cleaves Amyloid Beta Peptides at the α-Cleavage Site. [PDF]

Toxins (Basel), 2023
Futai E, Kawasaki H, Sato S, Daoudi K, Hidaka M, Tomita T, Ogawa T.   +6 more
europepmc   +1 more source

A Cubic Equation of State for Amyloid Plaque Formation [PDF]

arXiv, 2013
Protein function depends on both protein structure and amino acid (aa) sequence. Here we show that modular features of both structure and function can be quantified from the aa sequence alone for the amyloid 770 aa precursor protein A4. Both the new second order hydropathicity scale, based on evolutionary optimization (self-organized criticality), and ...
arxiv  

Monoclonal antibodies inhibit in vitro fibrillar aggregation of the Alzheimer beta-amyloid peptide. [PDF]

, 1996
Beka Solomon, Reine Koppel, Hanan Eizenberg, Tamar Katzav   +3 more
openalex   +1 more source

Alternative Method to Detect Neuronal Degeneration and Amyloid β Accumulation in Free-Floating Brain Sections With Fluoro-Jade

ASN Neuro, 2018
Fluoro-Jade is a fluorescein-derived fluorochrome which specifically binds to damaged neurons. Due to this characteristic, it is commonly used for the histochemical detection and quantification of neurodegeneration in mounted brain sections.
Irene L. Gutiérrez, Marta González-Prieto, Borja García-Bueno, Javier R. Caso, Juan C. Leza, José L. M. Madrigal   +5 more
doaj   +1 more source