Early Diagnosis of Alzheimer's disease by NIRF Spectroscopy and Nuclear Medicine-v.4.0 [PDF]
, 2011 There is an urgent need for the early detection of diseases such as Alzheimer’s (AD) and Cancers in order to enable their successful treatment. Cancer is the second major cause of death after Heart Disease, and AD is the third major cause of death
I Baianu
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Molecular Details of the Apolipoprotein E and the Amyloid Beta Peptide Interaction: Analysis of a Potential Binding Site Responsible for ApoE4 Misfolding [PDF]
, 2010 Alex Perálvarez‐Marín +4 more
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Angewandte Chemie International Edition, EarlyView.Copper binding triggers structural changes that expose a reactive disulphide bridge, enabling intrinsic Cu(II) reduction in folded proteins. SAXS, XAS, and QM/MM simulations reveal how globular proteins such as HSA and SOD1 employ disulphide‐mediated dynamics to modulate site accessibility and control copper redox chemistry.
Rebecca Sternke‐Hoffmann +9 more
wiley +1 more source
Concentration Dependent Transition of Membrane-Bound Beta-Stranded KIGAKI Peptides from Unstructured Monomers into Immobilized Amyloid Fibrils Observed by Solid-State 19F-NMR [PDF]
, 2013 Erik Strandberg +5 more
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Retraction: Protective Effect of HSP90 on Neuronal Cell Death-induced by beta-Amyloid Peptide
, 2020 Hyun Jung Lee +6 more
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Modulation of Amyloid Beta Peptide Aggregation by Apolipoprotein E Isoforms [PDF]
, 2012 Kanchan Garai, Carl Frieden
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Pyroglutamylated Amyloid-Beta Peptide Reverses Cross Beta-Sheets by a Prion-Like Mechanism [PDF]
, 2014 Jason O. Matos +2 more
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An Investigation of the Efficacy of Curcumin for Treatment of Alzheimer\u27s Disease [PDF]
, 2016 Curcumin is the primary curcuminoid found in the rhizome of the turmeric plant (Curcuma longa), responsible for the spice’s distinctive yellow color. Research conducted within the past two decades suggests that the compound may be an effective treatment ...
Patel, Parantap
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Angewandte Chemie International Edition, EarlyView.This study presents the synthesis and binding properties of a new family of o‐terphenyl‐based macrocycles, TP[n] (n = 2‐8). The trimer variant efficiently binds phenylalanine in water with a 10‐fold selectivity compared to other amino acids and aromatic neurotransmitters.
Swapnil Ghule +5 more
wiley +1 more source