Results 231 to 240 of about 118,464 (350)

Influence of Rosmarinic Acid on Zinc(II)–Amyloid Beta Coordination

European Journal of Inorganic Chemistry, EarlyView.
NMR and UV–vis investigations identify an Aβ–Zn–RA ternary complex that shifts metal‐mediated equilibria and promotes precipitation. Natural polyphenols such as rosmarinic acid (RA) are gaining attention for their antioxidant, anti‐inflammatory, and neuroprotective properties, attributed in part to their ability to chelate redox‐active metals. While RA'
Arian Kola, Daniela Valensin
wiley   +1 more source

The Kinetics and Thermodynamics of the Amyloid Beta Peptide

Amyloids are a category of protein structures where many individual polypeptide chains fold to form long β-sheet fibrils. These are strongly associated to many of today's incurableand fatal diseases, such as Alzheimer's and Parkinson's disease. However, the exact cause of toxicity and disease initiation remains elusive.
openaire   +1 more source

Nobiletin Ameliorates Aβ1–42‐Induced Cognitive Disorder and Mitochondrial Dysfunction via Targeting the Key Circadian Regulator Bmal1

Food Safety and Health, EarlyView.
Nobiletin (NOB) ameliorates Aβ‐induced Alzheimer’s pathology by restoring circadian rhythm via Bmal1. NOB rescues cognitive deficits, synaptic damage, and mitochondrial dysfunction in mice and neurons by enhancing Bmal1/Clock oscillations and downstream mitochondrial integrity, positioning circadian regulation as a therapeutic target for Alzheimer's ...
Huajing Gao, Qinglin Qu, Ning Wang, Xue Gao, Peihua Li, Yanquan Mou, Xiangrui Kong, Yannan Chen, Dapeng Li, Xintong Tan   +9 more
wiley   +1 more source

Aggregation States of Aβ_1-40, Aβ_1-42 and Aβp_3-42 Amyloid Beta Peptides: A SANS Study. [PDF]

Int J Mol Sci, 2019
Festa G, Mallamace F, Sancesario GM, Corsaro C, Mallamace D, Fazio E, Arcidiacono L, Garcia Sakai V, Senesi R, Preziosi E, Sancesario G, Andreani C.   +11 more
europepmc   +1 more source

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

Ibrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou, Cheng Wang, Yige Tan, Philip Lazarovici, Xiaoyan Wen, Shaoping Li, Wenhua Zheng   +6 more
wiley   +1 more source

Atrial cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala, Monika Przewłocka‐Kosmala   +1 more
wiley   +1 more source

Molecular imprinting for neurology: Materials, applications, and limitations

Ibrain, EarlyView.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma, Yingqi Ma, Claudia Marino, Alessandro Poma   +3 more
wiley   +1 more source

Differential effect of amyloid beta peptides on mitochondrial axonal trafficking depends on their state of aggregation and binding to the plasma membrane. [PDF]

Neurobiol Dis, 2018
Zhang L, Trushin S, Christensen TA, Tripathi U, Hong C, Geroux RE, Howell KG, Poduslo JF, Trushina E.   +8 more
europepmc   +1 more source

Decision letter for "Persistent homology and application on residues 1‐28 of amyloid beta peptide"

, 2020

openalex   +1 more source

P2‐314: Neuroprotective metallo‐complexes activate EGFR and inhibit amyloid‐beta peptide accumulation [PDF]

, 2008
Anthony R. White, Katherine A. Price, Gulay Filiz, Aphrodite Caragounis, Tai Du, Laura Bica, Colin L. Masters, Kevin J. Barnham, Peter J. Crouch, Paul S. Donnelly   +9 more
openalex   +1 more source