Results 261 to 270 of about 85,510 (321)

Advances in the Role of Antimicrobial Peptides in the Management of Sexually Transmitted Infections

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
The article reviews recent advancements in the use of antimicrobial peptides (AMPs) for the treatment and prevention of sexually transmitted infections (STIs), with a particular focus on research progress in combating infections such as gonorrhea, HIV, HSV, and Chlamydia, as well as the challenges and future directions in this field.
Shuangwen Xiao   +4 more
wiley   +1 more source

Proteomics Reveals Increased Periostin in Synovial Fluid From Canine and Human Anterior Cruciate Ligament Injury

open access: yesJournal of Orthopaedic Research, EarlyView.
ABSTRACT Posttraumatic osteoarthritis (PTOA) is a common sequela to anterior cruciate ligament (ACL) injury in humans and dogs. Identification of conserved targets between species may hasten biomarker identification and therapeutic development. To identify differentially regulated synovial fluid (SF) proteins in ACL injury, SF samples were collected ...
Sydney J. Womack   +4 more
wiley   +1 more source

Label‐Free Detection of π‐Stacking Interactions During Tryptophan Self‐Assembling Into Amyloid‐Like Structures Using Surface‐Enhanced Raman Scattering

open access: yesJournal of Raman Spectroscopy, EarlyView.
Tryptophan (Trp) self‐assembling into amyloid‐like fibrils was characterized for the first time with surface‐enhanced Raman scattering (SERS). It was possible to identify several spectral characteristics of the self‐assembled structures. This allowed to detect and monitor, as function of time, of several intermolecular interactions such as hydrogen ...
Gabriel Conishi Cardozo   +6 more
wiley   +1 more source

Amyloid Beta Peptides Block New Synapse Assembly by Nogo Receptor-Mediated Inhibition of T-Type Calcium Channels. [PDF]

open access: yesNeuron, 2017
Zhao Y   +15 more
europepmc   +1 more source

Magnetic Levitational Assembly of Differentiated SH‐SY5Y Cells for Aβ‐Induced 3D Alzheimer's Disease Modeling and Curcumin Screening

open access: yesMacromolecular Bioscience, EarlyView.
This study explores the 3D modeling of Alzheimer's disease using differentiated SH‐SY5Y spheroids via Magnetic levitation (MagLev) and investigates the neuroprotective effect of Curcumin. Differentiated spheroids displayed high viability and significant neuronal characteristics. Aβ 1‐42 exhibited neurotoxic effects on differentiated spheroids. Curcumin
Rumeysa Bilginer‐Kartal   +1 more
wiley   +1 more source

The production of amyloid beta peptide is a critical requirement for the viability of central neurons.

open access: bronze, 2003
Leigh D. Plant   +4 more
openalex  

Self‐Assembly of Noncanonical Peptides: A New Frontier in Cancer Therapeutics and Beyond

open access: yesMacromolecular Bioscience, EarlyView.
Representative examples of noncanonical peptide assemblies in anticancer therapeutics, biomaterials, regenerative medicine, molecular imaging, and catalysis are discussed, highlighting enzyme‐instructed self‐assembly as a valuable approach for constructing biomimetic and bioinspired materials that bridge the interface between biological systems and ...
Lin Bai, Meihui Yi, Bing Xu
wiley   +1 more source

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