Results 151 to 160 of about 122,310 (350)

Noninvasive imaging of amyloid‐beta and tau in rodent and nonhuman primate models

VIEW, EarlyView.
Imaging of amyloid‐beta plaque and tau accumulation in rodent and nonhuman primate model of Alzheimer's disease. Created in BioRender. Ni R. 2026. https://BioRender.com/a97h5ec Abstract Neurodegenerative diseases are characterized by the aberrant accumulation of protein aggregates.
Ruiqing Ni, Axel Rominger
wiley   +1 more source

人Kunitz型蛋白酶抑制剂-KD/APP的研究进展

Zhongguo shiyan zhenduanxue, 2013
牛胰蛋白酶抑制剂（Bovine pancreatic trypsin inhibitor,BPTI）具用广泛的蛋白酶抑制活性。但BPTI是一种异源性蛋白质,具有抗原性。淀粉样β蛋白前体（amyloid beta-pro-tein precursor,APP）中的Kunitz型蛋白酶抑制剂结构域(Kunitz protease inhibitor domain of amyloid protein precur-
孟威宏, 王虹蛟, 王强, 颜炜群
doaj  

Similar alternative splicing of a non-homologous domain in beta A4-amyloid protein precursor-like proteins.

, 1994
Rupert Sandbrink, Colin L. Masters, Konrad Beyreuther   +2 more
openalex   +1 more source

Transforming growth factor-alpha and beta-amyloid precursor protein share a secretory mechanism. [PDF]

, 1995
Joaquı́n Arribas, Joan Massagué
openalex   +1 more source

Amyloid Beta A4 Precursor Protein-Binding Family A Member 1 [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

Sialylation patterns in cerebral amyloid angiopathy

Brain Pathology, EarlyView.
This study is the first to localize and evaluate sialylation modifications in the context of Alzheimer's Disease and Cerebral Amyloid Angiopathy, revealing a unique disease‐specific increase in intravascular sialylation. Abstract Glycosylation is the most common form of post‐translational modification in the brain and becomes significantly altered in ...
Caitlyn Fastenau, Rebecca Crisp, Mallory Keating, Elizabeth Ochoa, Timothy E. Richardson, Margaret E. Flanagan, Jamie M. Walker, Sarah C. Hopp, Kevin F. Bieniek   +8 more
wiley   +1 more source

Apolipoprotein E and Alzheimer’s disease: The influence of apolipoprotein E on amyloid- and other amyloidogenic proteins [PDF]

, 2017
Agosta, Alata, Albert A. Davis, Aleshkov, Allen, Alzheimer, Anderson, Atagi, Bailey, Bales, Bales, Bales, Basak, Bateman, Beffert, Beffert, Beffert, Bell, Bell, Benilova, Benjamin, Bernardi, Bertram, Bien-Ly, Bien-Ly, Biere, Brecht, Brunden, Bu, Caselli, Castellano, Castellano, Cedazo-Mínguez, Cheng, Cirrito, Cirrito, Cole, Cooper, Corder, Corder, Cotman, David M. Holtzman, de la Torre, Deane, Deane, DeMattos, Drory, Emamzadeh, Engelborghs, Esparza, Evans, Fabre, Fagan, Fagan, Farrer, Fryer, Fryer, Funato, Gallardo, Gallyas, Games, Gao, Garai, Govone, Greenberg, Grehan, Guerreiro, Gustafson, Halliday, Hardy, Harris, Harris, Heinonen, Hirsch-Reinshagen, Hirsch-Reinshagen, Holtzman, Holtzman, Holtzman, Holtzman, Hone, Hong, Hu, Huang, Huang, Huang, Hughes, Irizarry, Irwin, Irwin, Irwin, Iwai, Jakes, Jarrett, Jason D. Ulrich, Jellinger, Ji, Jiang, Jonsson, Josephs, Kanekiyo, Kehoe, Kim, Kim, Kim, Klunk, Klunk, Koistinaho, Koldamova, Korczyn, Kotzbauer, Lacomblez, LaDu, LaDu, Lashuel, Lee, Li, Li, Li, Li, Liao, Lill, Lippa, Liu, Liu, Ma, Mahley, Mahley, Mak, Mandrekar, Marchesi, Marder, Martin, Masliah, Mathis, Mattila, Mauch, McKee, Mikolaenko, Morris, Mui, Nalivaeva, Namba, Narita, Nathan, Nelson, Nielsen, Ohm, Panegyres, Paresce, Paresce, Pfeifer, Pfrieger, Pitas, Poirier, Praline, Rebeck, Rebeck, Reiman, Riemenschneider, Rockenstein, Roses, Roychaudhuri, Saavedra, Sabbagh, Saito, Sanan, Schmechel, Shaffer, Shibata, Siderowf, Srinivasan, Strittmatter, Strittmatter, Strittmatter, Sullivan, Sunderland, Szaruga, Tamamizu-Kato, Tesseur, Thal, Theendakara, Tien-Phat V. Huynh, Tiraboschi, Tokuda, Tsuang, Ulrich, Van Gool, van Horssen, Verghese, Wahrle, Wahrle, Wakabayashi, Wang, Watanabe, Wilson, Wisniewski, Wisniewski, Withers, Wood, Wyss-Coray, Yang, Ye, Yeh, Yuan, Zerbinatti, Zhang, Zhang, Zlokovic   +207 more
core   +2 more sources

Synaptic Vesicle Glycoprotein 2A Suppresses Amyloidogenesis Beyond Its Synaptic Role: A Novel Mechanism Disrupting BACE1 Binding and Altering APP Localization. [PDF]

Aging Cell
Synaptic vesicle glycoprotein 2A, the newly identified APP‐binding protein, reduces amyloid‐β plaque deposition in Alzheimer's disease by suppressing the amyloidogenic pathway through inhibition of BACE1‐APP interaction and alteration of APP endosomal‐lysosomal localization.
Wang X, Zhang Q, Zhang X, Liu J, Zhang J, Liu C, Cui Y, Song Q, Hou Y, Wang Y, Cao M, Wang P.   +11 more
europepmc   +2 more sources

Dataset for the Amyloid-beta precursor protein antibody screening study

, 2023
Kathleen Southern
openalex   +1 more source

14‐3‐3σ up‐regulation in the temporal cortex associates with tau pathology and reactive astroglia in Lewy body disorders

Brain Pathology, EarlyView.
14‐3‐3 protein homeostasis is disrupted in Lewy body pathology, showing a diminution of six isotypes and overexpression of stratifin. The latter was associated with stratifin colocalization with tau pathology and reactive astrocytes. Platelets, as a peripheral biomarker source, mirrored inversely cortical 14‐3‐3 gene expression patterns in dementia ...
Laura Marsal‐García, Jorge Mena, Carol‐Ann Lao, David Adamuz, Laura Arnaldo, Cristina Carrato, Alex Menendez, Daniela Samaniego, Dolores Vilas, Lourdes Ispierto, Anna Planas, Ramiro Alvarez, Pau Pastor, Katrin Beyer   +13 more
wiley   +1 more source