Results 301 to 310 of about 249,317 (377)

The use of left ventricular ejection fraction in the diagnosis and management of heart failure. A clinical consensus statement of the Heart Failure Association (HFA) of the ESC, the Heart Failure Society of America (HFSA), and the Japanese Heart Failure Society (JHFS)

European Journal of Heart Failure, EarlyView.
Abstract This clinical consensus statement revisits the role of left ventricular ejection fraction (LVEF) as a measurement of cardiac function, a prognostic marker and a major criterion to classify patients with heart failure, and gives new advice for clinical practice.
Giuseppe M.C. Rosano, John R. Teerlink, Koichiro Kinugawa, Antoni Bayes‐Genis, Ovidiu Chioncel, James Fang, Barry Greenberg, Nasrien E. Ibrahim, Teruhiko Imamura, Takayuki Inomata, Koichiro Kuwahara, Brenda Moura, Anekwe Onwuanyi, Naoki Sato, Gianluigi Savarese, Yasuhiko Sakata, Nancy Sweitzer, Jane Wilcox, Kazuhiro Yamamoto, Marco Metra, Andrew J.S. Coats   +20 more
wiley   +1 more source

Exploring Bioinspired Ln3+ Complexes for Cu2+ Detection: Design and Efficacy as MRI Contrast Agents

European Journal of Inorganic Chemistry, EarlyView.
Gd3+ complexes bearing a bioinspired Cu2+‐binding site derived from ATCUN are studied as MRI contrast agents. The presence of two amino acids (GH) is necessary to bind Cu2+ and trigger a relaxivity increase. This is due to a higher number of H2O retained close to Gd3+ through H‐bonding with Cu2+. Remarkably, the system remains selective for Cu2+ vs Zn2+
Martina Sanadar, Katharina Zimmeter, Harlei Martin, Agnès Pallier, Bertrand Vileno, Peter Faller, Angélique Sour, Célia S. Bonnet   +7 more
wiley   +1 more source

Benzochalcogenodiazoles, synthesis and applications in medicinal chemistry and photomedicine.

European Journal of Organic Chemistry, Accepted Article.
Benzochalcogenodiazoles BXDs (BOD: benzoxadiazole, BTD: benzothiadiazole, or BSD: benzoselenadiazole) are aromatic bicyclic compounds, containing chalcogen atoms, with applications ranging from material to medicinal chemistry. The recent developments in their preparation and functionalization are taking advantage of new methodologies such as C‐H ...
Jean-Elie Zheng, Xavier Franck, Thibault Gallavardin   +2 more
wiley   +1 more source

Evaluation of the Effects of Thymoquinone on RAGE/NOX4 Expressions and Brain Tissue Morphometry in Experimental Alzheimer's Disease Induced by Amyloid Beta 1-42 Peptide. [PDF]

Biomolecules
Ateş Ş, Ülger H, Uçar S, Okan A, Ocak M, Güvenilir E, Şükranlı ZY, Kaymak E, Doğanyiğit Z, Taheri S, Yilmaz S.   +10 more
europepmc   +1 more source

A Comprehensive Review on Capillary Electrophoresis–Mass Spectrometry in Advancing Biomolecular Research

ELECTROPHORESIS, EarlyView.
ABSTRACT This review provides an in‐depth exploration of capillary electrophoresis–mass spectrometry (CE–MS) in biomolecular research from 2020 to 2024. CE–MS emerges as a versatile and powerful tool due to its numerous advantages, facilitating the analysis of various biomolecules, including proteins, peptides, oligonucleotides, and other metabolites ...
Laura Pont, María Vergara‐Barberán, Enrique Javier Carrasco‐Correa   +2 more
wiley   +1 more source

Linking higher amyloid beta 1-38 (Aβ(1-38)) levels to reduced Alzheimer's disease progression risk. [PDF]

Alzheimers Dement
Schneider LS, Freiesleben SD, van Breukelen G, Wang X, Brosseron F, Heneka MT, Teipel S, Kleineidam L, Stark M, Roy-Kluth N, Wagner M, Spottke A, Schmid M, Roeske S, Laske C, Munk MH, Perneczky R, Rauchmann BS, Buerger K, Janowitz D, Düzel E, Glanz W, Jessen F, Rostamzadeh A, Wiltfang J, Bartels C, Kilimann I, Schneider A, Fliessbach K, Priller J, Spruth EJ, Hellmann-Regen J, Peters O.   +32 more
europepmc   +1 more source

Role of membrane biophysics in Alzheimer\u27s–related cell pathways [PDF]

, 2015
Bungart, Brittani L, Lee, James C-M., Yang, Xiaoguang, Zhu, Donghui, Zhumadilov, Zhaxybay   +4 more
core   +1 more source

Nicotine enhances the biosynthesis and secretion of transthyretin from the choroid plexus in rats: implications for beta-amyloid formation.

, 2000
Ming D. Li, Justin K. Kane, Shannon G. Matta, William S. Blaner, Burt M. Sharp   +4 more
openalex  

Exploring biomarkers of neurodegeneration in epilepsy: Critical insights

Epileptic Disorders, EarlyView.
Abstract The advent of biofluid biomarkers for neurodegenerative disorders has precipitated a surge in recent evidence regarding their role in epilepsy. In this literature review, we examine the diagnostic, prognostic, and therapeutic potential of several biomarkers, including amyloid‐beta (Aβ) protein, total (t‐tau), phosphorylated tau (p‐tau) protein,
Rida Farhan, Syeda Amrah Hashmi, Jaideep Kapur, Anelyssa D'Abreu, Vineet Punia, Carol Manning, Vanessa L. Smith, Ifrah Zawar   +7 more
wiley   +1 more source