Results 251 to 260 of about 82,488 (290)

Diverse Interactions of Sterols with Amyloid Precursor Protein Transmembrane Domain Can Shift Distribution Between Alternative Amyloid-β Production Cascades in Manner Dependent on Local Lipid Environment. [PDF]

Int J Mol Sci
Volynsky PE, Urban AS, Pavlov KV, Bershatsky YV, Bocharova OV, Kryuchkova AK, Zlobina VV, Gavrilenkova AA, Dolotova SM, Kamynina AV, Zangieva OT, Taldaev A, Batishchev OV, Okhrimenko IS, Rakitina TV, Efremov RG, Bocharov EV.   +16 more
europepmc   +1 more source

Serum Biomarkers in Atlantic Salmon for Differential Diagnosis of Cardiomyopathy Syndrome and Pancreas Disease: Proteomic Identification of Serum Fibrinogen to Enhance Troponin Immunoassay as Optimal Diagnostic Approach

Journal of Fish Diseases, EarlyView.
ABSTRACT Cardiac viral diseases are among the major causes of economic losses in Atlantic salmon (Salmo salar L.) aquaculture. These include cardiomyopathy syndrome (CMS) caused by piscine myocarditis virus (PMCV) and pancreas disease (PD) caused by Atlantic salmonid alphavirus (SAV).
Francesca Riva, Lauren Elaine Black, Kim D. Thompson, Philippe Sourd, Andrei Bordeianu, Christopher C. Chadwick, Hooman Moghadam, Jorge Del‐Pozo, Janina Costa, Richard Burchmore, Nicola Brady, Lewis Moore, Suzanne McGill, Mark McLaughlin, Peter David Eckersall   +14 more
wiley   +1 more source

SIL1 improves cognitive impairment in APP23/PS45 mice by regulating amyloid precursor protein processing and Aβ generation. [PDF]

Zool Res
Wang Q, Jiang Y, Meng Z, Dong X, Hu D, Ji L, Zhou W, Song W.   +7 more
europepmc   +1 more source

Novel murine closed‐loop auditory stimulation paradigm elicits macrostructural sleep benefits in neurodegeneration

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Boosting slow‐wave activity (SWA) by modulating slow waves through closed‐loop auditory stimulation (CLAS) might provide a powerful non‐pharmacological tool to investigate the link between sleep and neurodegeneration. Here, we established mouse CLAS (mCLAS)‐mediated SWA enhancement and explored its effects on sleep deficits in neurodegeneration,
Inês Dias, Sedef Kollarik, Michelle Siegel, Christian R. Baumann, Carlos G. Moreira, Daniela Noain   +5 more
wiley   +1 more source

Comparison of background characteristics and neuropathology findings between medico-legal autopsy cases with traumatic axonal injury, vascular axonal injury, or absence of axonal injury in β-amyloid precursor protein stain. [PDF]

Int J Legal Med
Narayan G, Oura P.
europepmc   +1 more source

Neuroimmune pathophysiology of long COVID

Psychiatry and Clinical Neurosciences, EarlyView.
Although COVID‐19 was originally considered a respiratory illness, it is now well established that SARS‐CoV‐2 infection can have far‐reaching impacts on the nervous system. Neurological symptoms such as chemosensory dysfunction are frequently observed during acute infection and approximately 10% of COVID‐19 cases will go on to develop new or persistent
Janna K. Moen, Christopher A. Baker, Akiko Iwasaki   +2 more
wiley   +1 more source

Efficacy of Sailuotong on neurovascular unit in amyloid precursor protein/presenilin-1 transgenic mice with Alzheimer's disease. [PDF]

J Tradit Chin Med
Linjuan S, Chengfu LI, Jiangang L, Nannan LI, Fuhua H, Dandan Q, Zhuang T, Min Z, Wenjie C, Xiaohui Z, Chenguang T, Dong C, Jiangxia Q, Yang L, Xiao L, Xiaoying Z, Yunling Z.   +16 more
europepmc   +1 more source

The role of the oral microbiome, host response, and periodontal disease treatment in Alzheimer's disease: A primer

Periodontology 2000, EarlyView.
Abstract Background Alzheimer‘s disease (AD) is the leading cause of cognitive impairment and dementia in elderly patients worldwide. There is increasing evidence that periodontal disease may have an important role in the complex, multifactorial pathogenesis of AD. Aim This narrative review aims to (1) highlight the current understanding of the role of
Jaclyn C. Chalmers, Yvonne L. Hernandez‐Kapila   +1 more
wiley   +1 more source

RABGAP1 acts as a sensor to facilitate sorting and processing of amyloid precursor protein

Eden J, Kaufman JG, Cattin-Ortola J, Benedetti L, Nieuwenhuis B, Owen DJ, Lippincott-Schwartz J, Munro S, Gershlick DC.   +8 more
europepmc   +1 more source