Results 151 to 160 of about 70,398 (322)

Advancements in research on lactate dehydrogenase A in urinary system tumors

open access: yesBMC Urology
Tumors of the urinary system, such as prostate cancer, bladder cancer, and renal cell carcinoma, are among the most prevalent types of tumors. They often remain asymptomatic in their early stages, with some patients experiencing recurrence or metastasis ...
Zhiyuan Zhuo, Yu Wang, Yifan Xu
doaj   +1 more source

Microscopic and molecular aspects of skeletal muscle alterations in cerebral palsy

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Cerebral palsy, caused by non‐progressive brain injury, is frequently accompanied by skeletal muscle alterations. This review synthesizes current evidence from muscle biopsy studies, revealing cellular and molecular adaptations in muscle tissue. Abstract Cerebral palsy (CP), the most prevalent childhood‐onset motor disability, frequently entails ...
Sebastian Edman   +4 more
wiley   +1 more source

Rates of Performance Loss and Neuromuscular Activity in Men and Women During Cycling: Evidence for A Common Metabolic Basis of Muscle Fatigue [PDF]

open access: yes, 2017
The durations that muscular force and power outputs can be sustained until failure fall predictably on an exponential decline between an individual’s 3-s burst maximum to the maximum performance they can sustain aerobically.
Bundle, Matthew W.   +2 more
core   +1 more source

Quantitative assessment of gait alterations and variability in sulky‐driven Standardbred trotters after a standardised exercise test

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Assessment of equine metabolic and locomotory responses to quantified levels of physical exercise is needed to support the creation of tailored protocols for optimal training adaptation. The locomotory response to exercise in horses is not fully understood.
Rhana Mackie Aarts   +5 more
wiley   +1 more source

Katarak Diabetes

open access: yesJKS (Jurnal Kedokteran Syiah Kuala), 2011
Abstrak. Sebagian besar  (78%) pemecahan glukosa didalam lensa melalui jalur glikolisis anaerobik, 14% melalui jalur pentosa fosfat, sekitar 5% melalui jalur poliol.
Arti Lukitasari
doaj  

Propionibacterium acnes evades microbicidal phagocytosis by inhibiting the mitochondrial biogenesis of nucleus pulposus cells

open access: yesThe FEBS Journal, EarlyView.
P. acnes infection impairs the mitochondrial biogenesis of nucleus pulposus cells (NPCs) through the AMPK/SIRT‐1/PGC‐1α signaling pathway. This results in impaired mitochondria that are unable to generate sufficient ATP, and impaired delivery of mitochondrial reactive oxygen species to carry out the bactericidal process effectively.
Lemeng Ren   +9 more
wiley   +1 more source

LAG‐3+ Regulatory T Cells Suppress Effector Function of T Cells and Allow Their Proliferation Into Regulatory T Cells

open access: yesImmunology, EarlyView.
LAG‐3+ regulatory T cells suppress the effector but not the proliferative response of naïve cognate antigen‐specific CD4+ T cells in vivo. The suppressed T cells display upregulation of immune checkpoints and downregulation of pro‐inflammatory pathways with enhanced TCR signaling and reduced oxidative metabolism.
Avijit Dutta   +7 more
wiley   +1 more source

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