Results 1 to 10 of about 64,230 (279)
Biology, 2016 Anaphase B spindle elongation is characterized by the sliding apart of overlapping antiparallel interpolar (ip) microtubules (MTs) as the two opposite spindle poles separate, pulling along disjoined sister chromatids, thereby contributing to chromosome ...
Jonathan M. Scholey +2 more
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The Long and Viscous Road: Uncovering Nuclear Diffusion Barriers in Closed Mitosis [PDF]
PLoS Comput Biol 10(7): e1003725, 2014, 2014 During Saccharomyces cerevisiae closed mitosis, parental identity is sustained by the asymmetric segregation of ageing factors. Such asymmetry has been hypothesized to occur via diffusion barriers, constraining protein lateral exchange in cellular membranes. Diffusion barriers have been extensively studied in the plasma membrane, but their identity and
Marquez-Lago, Tatiana T., Zavala, Eder
arxiv +7 more sources
Modeling Dual Pathways for the Metazoan Spindle Assembly Checkpoint [PDF]
Proc. Natl. Acad. Sci. 103 16758-16763 (2006), 2006 Using computational modelling, we investigate mechanisms of signal transduction focusing on the spindle assembly checkpoint where a single unattached kinetochore is able to signal to prevent cell cycle progression. This inhibitory signal switches off rapidly once spindle microtubules have attached to all kinetochores.
Acquaviva +29 more
arxiv +5 more sources
Blocking microtubule deacetylation inhibits anaphase chromosome movements in crane-fly spermatocytes. [PDF]
PLoS ONEChromosome movement speeds during anaphase are regulated by depolymerization of microtubules. Several models describe chromosome movement during cell division but none of them consider post-translational modifications of tubulin, even though such ...
Maral Janan +2 more
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Aberrant meiotic behavior in
BMC Plant Biology, 2002 Background Agave tequilana Weber var. azul, is the only one variety permitted by federal law in México to be used for tequila production which is the most popular contemporary alcoholic beverage made from agave and recognized worldwide.
Rodríguez-Garay Benjamin +1 more
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Spatiotemporal regulation of MELK during mitosis [PDF]
Frontiers in Cell and Developmental BiologyMaternal Embryonic Leucine Zipper Kinase (MELK) has been studied intensively in recent years due to its overexpression in multiple cancers. However, the cell biology of MELK remains less characterized despite its well-documented association with mitosis.
Sreemita Majumdar, Song-Tao Liu
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Single-motor and multi-motor motility properties of kinesin-6 family members
Biology Open, 2022 Kinesin motor proteins are responsible for orchestrating a variety of microtubule-based processes including intracellular transport, cell division, cytoskeletal organization, and cilium function.
Andrew Poulos +2 more
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eLife, 2022 During anaphase B, molecular motors slide interpolar microtubules to elongate the mitotic spindle, contributing to the separation of chromosomes. However, sliding of antiparallel microtubules reduces their overlap, which may lead to spindle breakage ...
Manuel Lera-Ramirez +2 more
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Mechanical Mechanisms of Chromosome Segregation
Cells, 2021 Chromosome segregation—the partitioning of genetic material into two daughter cells—is one of the most crucial processes in cell division. In all Eukaryotes, chromosome segregation is driven by the spindle, a microtubule-based, self-organizing ...
Maya I. Anjur-Dietrich +2 more
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Frontiers in Molecular Biosciences, 2021 In normal anaphase cells, telomeres of each separating chromosome pair are connected to each other by tethers. Tethers are elastic at the start of anaphase: arm fragments cut from anaphase chromosomes in early anaphase move across the equator to the ...
Arthur Forer +7 more
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