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Anaphase B [PDF]

Biology, 2016
Anaphase B spindle elongation is characterized by the sliding apart of overlapping antiparallel interpolar (ip) microtubules (MTs) as the two opposite spindle poles separate, pulling along disjoined sister chromatids, thereby contributing to chromosome ...
Jonathan M. Scholey, Gul Civelekoglu-Scholey, Ingrid Brust-Mascher   +2 more
doaj   +5 more sources

Spatiotemporal control of mitotic exit during anaphase by an aurora B-Cdk1 crosstalk

eLife, 2019
According to the prevailing ‘clock’ model, chromosome decondensation and nuclear envelope reformation when cells exit mitosis are byproducts of Cdk1 inactivation at the metaphase-anaphase transition, controlled by the spindle assembly checkpoint. However,
Olga Afonso, Colleen M Castellani, Liam P Cheeseman, Jorge G Ferreira, Bernardo Orr, Luisa T Ferreira, James J Chambers, Eurico Morais-de-Sá, Thomas J Maresca, Helder Maiato   +9 more
doaj   +2 more sources

Spatiotemporal regulation of MELK during mitosis [PDF]

Frontiers in Cell and Developmental Biology
Maternal Embryonic Leucine Zipper Kinase (MELK) has been studied intensively in recent years due to its overexpression in multiple cancers. However, the cell biology of MELK remains less characterized despite its well-documented association with mitosis.
Sreemita Majumdar, Song-Tao Liu
doaj   +2 more sources

Anaphase A: Disassembling Microtubules Move Chromosomes toward Spindle Poles

Biology, 2017
The separation of sister chromatids during anaphase is the culmination of mitosis and one of the most strikingly beautiful examples of cellular movement.
Charles L. Asbury
doaj   +2 more sources

Blocking microtubule deacetylation inhibits anaphase chromosome movements in crane-fly spermatocytes. [PDF]

PLoS ONE
Chromosome movement speeds during anaphase are regulated by depolymerization of microtubules. Several models describe chromosome movement during cell division but none of them consider post-translational modifications of tubulin, even though such ...
Maral Janan, Jess MacPherson, Arthur Forer   +2 more
doaj   +2 more sources

Cdk1 inactivation induces post-anaphase-onset spindle migration and membrane protrusion required for extreme asymmetry in mouse oocytes

Nature Communications, 2018
Female meiotic divisions are asymmetric with the formation of large oocytes and small polar bodies, thought to result from cortical spindle placement before anaphase.
Zhe Wei, Jessica Greaney, Chenxi Zhou, Hayden A. Homer   +3 more
doaj   +2 more sources

Chromosome Bridges Maintain Kinetochore-Microtubule Attachment throughout Mitosis and Rarely Break during Anaphase. [PDF]

PLoS ONE, 2016
Accurate chromosome segregation during cell division is essential to maintain genome stability, and chromosome segregation errors are causally linked to genetic disorders and cancer.
Judit Pampalona, Emanuele Roscioli, William T Silkworth, Brent Bowden, Anna Genescà, Laura Tusell, Daniela Cimini   +6 more
doaj   +2 more sources

Cleavage of Cohesin by the CD Clan Protease Separin Triggers Anaphase in Yeast [PDF]

Cell, 2000
F. Uhlmann, D. Wernic, M. Poupart, E. Koonin, K. Nasmyth   +4 more
semanticscholar   +2 more sources

Two Distinct Pathways Remove Mammalian Cohesin from Chromosome Arms in Prophase and from Centromeres in Anaphase [PDF]

Cell, 2000
I. Waizenegger, Silke Hauf, A. Meinke, J. Peters   +3 more
semanticscholar   +2 more sources

Single-motor and multi-motor motility properties of kinesin-6 family members

Biology Open, 2022
Kinesin motor proteins are responsible for orchestrating a variety of microtubule-based processes including intracellular transport, cell division, cytoskeletal organization, and cilium function.
Andrew Poulos, Breane G. Budaitis, Kristen J. Verhey   +2 more
doaj   +1 more source