Results 111 to 120 of about 10,975 (239)

Attenuation of myocardial reperfusion injury in pigs by Mirococept, a membrane-targeted complement inhibitor derived from human CR1 [PDF]

, 2017
Objectives Membrane-targeted application of complement inhibitors may ameliorate ischemia/reperfusion (I/R) injury by directly targeting damaged cells. We investigated whether Mirococept, a membrane-targeted, myristoylated peptidyl construct derived from
Banz, Yara, Csizmadia, Eva, Haeberli, André, Hess, Otto M., Meier, Pascal, Mettler, Daniel, Rieben, Robert, Robson, Simon C., Shaw, Sidney, Smith, Richard A.   +9 more
core  

Pathobiochemistry of Sepsis [PDF]

, 1986
Duswald, Karl-Heimo, Fritz, Hans, Inthorn, D., Jochum, Marianne, Welter, H. F., Witte, J.   +5 more
core   +1 more source

457 Elucidating individual complement activation products in driving inflammation and progressive hydrocephalus in murine neonatal germinal matrix hemorrhage

Journal of Clinical and Translational Science
Objectives/Goals: Germinal matrix hemorrhage (GMH) is a devastating disease of infancy that results in brain-related pathologies. Following rupture of vasculature in the brain, red blood cell (RBC) lysis, and hemoglobin breakdown results in heme/iron ...
Devin Hatchell, Mohammed Alshareef, Ramin Eskandari, Stephen Tomlinson   +3 more
doaj   +1 more source

Anaphylatoxin and Anaphylaxis: VII. Peptone Anaphylatoxin [PDF]

Journal of Infectious Diseases, 1917
F. G. Novy, P. H. DeKruif, F. O. Novy
openaire   +1 more source

The tangled web [PDF]

, 1990
Dorsch, Walter, Fritz, Hans, Jochum, Marianne   +2 more
core   +1 more source

The complement cascade in lung injury and disease

Respiratory Research
Background The complement system is an important arm of immune defense bringing innate and adaptive immunity. Although originally regarded as a major complementary defense mechanism against pathogens, continuously emerging evidence has uncovered a ...
M. G. Detsika, K. Palamaris, I. Dimopoulou, A. Kotanidou, S. E. Orfanos   +4 more
doaj   +1 more source

Biophysical and structural studies of fibulin-2

Scientific Reports
Fibulin-2 is a multidomain, disulfide-rich, homodimeric protein which belongs to a broader extracellular matrix family. It plays an important role in the development of elastic fiber structures.
Anil A. Sohail, M. Kristian Koski, Lloyd W. Ruddock   +2 more
doaj   +1 more source

The role of the anaphylatoxins in health and disease.

Molecular Immunology, 2009
A. Klos, A. Tenner, Kay O. Johswich, Rahasson R. Ager, E. Reis, J. Köhl   +5 more
semanticscholar   +1 more source

Endothelial-to-mesenchymal transition and renal fibrosis in ischaemia/reperfusion injury are mediated by complement anaphylatoxins and Akt pathway.

Nephrology, Dialysis and Transplantation, 2014
C. Curci, G. Castellano, A. Stasi, C. Divella, A. Loverre, M. Gigante, S. Simone, M. Cariello, V. Montinaro, G. Lucarelli, P. Ditonno, M. Battaglia, A. Crovace, F. Staffieri, B. Oortwijn, E. V. van Amersfoort, L. Gesualdo, G. Grandaliano   +17 more
semanticscholar   +1 more source

Distinct Roles of the Anaphylatoxins C3a and C5a in Dendritic Cell–Mediated Allergic Asthma

Journal of Immunology, 2014
Carsten Engelke, Anna V. Wiese, I. Schmudde, F. Ender, Heike A. Ströver, T. Vollbrandt, P. König, Y. Laumonnier, J. Köhl   +8 more
semanticscholar   +1 more source