Results 191 to 200 of about 10,975 (239)

HEPATIC ANAPHYLATOXIN

Journal of the American Medical Association, 1924
The liver is the first organ for which a function of internal secretion was predicted by Claude Bernard. Our knowledge of hepatic physiology is so scanty, however, that modern textbooks on endocrinology rarely mention the liver as a possible site of hormone formation.
W. H. MANWARING, VAUGHN M. HOSEPIAN, DOROTHY F. PORTER, JAMES R. ENRIGHT   +3 more
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Anaphylatoxin Formation in Sepsis

Archives of Surgery, 1988
Complement activation and anaphylatoxin formation were studied in 27 septic patients. The patients were treated with antibiotics and high-dose corticosteroids. Blood samples were drawn on admission and every week thereafter. Plasma levels of complement components C1INH, C3, C4, and C5 were low before the start of treatment but were above normal one ...
A, Bengtson, M, Heideman
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Histamine Release by Anaphylatoxin

Nature, 1951
EARLY studies of the mechanism of anaphylaxis led to two apparently contradictory views : the so-called ‘humoral theory’, according to which the blood is the site of production of a toxin, the anaphylatoxin1–4; and the ‘cellular theory’, which localizes the anaphylactic reaction in the cells, and assumes that this reaction causes the release of ...
M, ROCHA E SILVA, O, BIER, M, ARONSON
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THE HEPATIC ANAPHYLATOXIN

Journal of the American Medical Association, 1924
In previous papers it was shown that characteristic anaphylactic contractions of the urinary bladder 1 and of the gastro-intestinal tract 2 do not take place in dehepatized anaphylactic dogs. The conclusion was drawn that the typical anaphylactic contractions of these organs are due to chemical products (hepatic anaphylatoxins) explosively formed or ...
W. H. MANWARING, V. M. HOSEPIAN, F. I. O'NEILL, H. BING MOY   +3 more
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Anaphylatoxin and Anaphylaxis: XI. Ultra-Filtration and Fractionation of Anaphylatoxin

Journal of Infectious Diseases, 1919
Despite the large amount of study on the nature of anaphylatoxin and of the mechanism of its formation, little if any attempt has been made to isolate the toxic principle on one or the other of the protein fractions of the serum. Various serum principles having physiologic activity, but of unknown chemical nature, have been isolated on the protein ...
P. H. De Kruif, A. H. Eggerth
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The anaphylatoxin-forming system

Ergebnisse der Physiologie Biologischen Chemie und Experimentellen Pharmakologie, 1967
Introduct ion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . t 60 I. Format ion of anaphylatoxin. Evidence for an enzymic mechanism . . . . . t 62 II . The components of the anaphyla toxin system . . . . . . . . . . . . . . . 165 A. The anaphylatoxin-forming enzymes . . . . . . . . . . . . . . . . . 165 1. The cobra enzyme . . . . . . . .
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Revealing the signaling of complement receptors C3aR and C5aR1 by anaphylatoxins

Nature Chemical Biology, 2023
Yue Wang, Weiyi Liu, Youwei Xu, Xinheng He, Qingning Yuan, Ping Luo, Wenjia Fan, Jingpeng Zhu, Xinyue Zhang, Xi Cheng, Yi Jiang, H. E. Xu, Y. Zhuang   +12 more
semanticscholar   +1 more source

Anaphylatoxin generation in acute pancreatitis

Journal of Surgical Research, 1989
Fifty-one patients with elevated serum amylase and clinical signs of acute pancreatitis were studied prospectively. The concentrations of anaphylatoxins (C3a and C5a) were measured with a radioimmunoassay and the activity of their inactivator was determined.
L, Roxvall, A, Bengtson, M, Heideman
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Anaphylatoxins in fresh‐frozen plasma

Transfusion, 1997
BACKGROUND: Fresh‐frozen plasma (FFP) is widely used in patients with coagulation disorders and simultaneous complement activation. Complement activation in FFP itself is poorly investigated. STUDY DESIGN AND METHODS: The concentration of anaphylatoxins C3a and C5a, the complement precursors C1q and factor B, and complement function were measured in 40
J, Sonntag, B, Stiller, M M, Walka, R F, Maier   +3 more
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Designing synthetic superagonists of C3a anaphylatoxin

Biochemistry, 1991
An extensive structure-activity study of synthetic analogues of the C3a anaphylatoxin was conducted. Our goal was to map C3a-C3a receptor interactions by designing synthetic analogue molecules having maximal biologic potency. Nonspecific binding of the polycationic C3a to polyanionic molecules on cellular surfaces often obscures specific binding to the
J A, Ember, N L, Johansen, T E, Hugli
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