Results 61 to 70 of about 10,975 (239)
Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.ABSTRACT The current study is aimed to reveal the phytoprofile of Selaginella inaequalifolia (Hook. & Grev.) Spring using GC–MS and predict the drug properties, toxicity, biological properties of S. inaequalifolia ethanolic extracts (SiEE) using in silico methods and in vitro toxicity assays, namely, MTT and BSLB assay.
Johnson Marimuthu Alias Antonysamy +4 more
wiley +1 more source
Journal of Immunology, 1978 Peptides C3a and C5a, also known as anaphylatoxins, are derived from C components C3 and C5 and have previously been reported to exhibit chemotactic activity.
H. N. Fernández +3 more
semanticscholar +1 more source
Discovery of functionally selective C5aR2 ligands: novel modulators of C5a signalling. [PDF]
, 2016 The complement cascade is comprised of a highly sophisticated network of innate immune proteins that are activated in response to invading pathogens or tissue injury. The complement activation peptide, C5a, binds two seven transmembrane receptors, namely
Blaskovich, M.A. +11 more
core +1 more source
The insider's perspective: The intracellular complosome and immune cell dynamics in cancer
Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.Intracellular complement (complosome) shapes the tumour immune microenvironment. Complosome's role in cancer is underrecognised yet central to tumour immunity. C3/C5‐driven complosome signals rewire T‐cell activation, fate and metabolism. Complosome activity can promote pro‐tumour immune cell function.
Alexandra Bennion +2 more
wiley +1 more source
Frontiers in Immunology, 2019 Envenomation by Bothrops snakes causes prominent local effects, including pain, oedema, local bleeding, blistering and necrosis, and systemic manifestations, such as hemorrhage, hypotension, shock and acute renal failure.
Lygia Samartin Gonçalves Luchini +3 more
doaj +1 more source
Present State of Knowledge on Processes of Healing in Collagen Structures [PDF]
, 1982 Introduction: The greatly increasing number of sport injuries among both youth and older people and the diversity of these injuries necessitates an individual treatment of the patient and his or her injury.
Meulen, J.C.H.M. (Jacques) van der
core +1 more source
Bufalin Inhibits Cytokine Storm by Regulating TLR4/TLR3 Signaling Pathway
Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.ABSTRACT Background Bufalin is one main component of the dried venom from Bufo gargarizans Cantor, which has anti‐tumor, cardiotonic, anti‐inflammatory and other physiological activities. However, in recent years, researchers have mainly paid attention to its anti‐tumor effect and neglected its anti‐inflammatory effect.
Xixi Liu +11 more
wiley +1 more source
Downsizing a human inflammatory protein to a small molecule with equal potency and functionality [PDF]
, 2013 A significant challenge in chemistry is to rationally reproduce the functional potency of a protein in a small molecule, which is cheaper to manufacture, non-immunogenic, and also both stable and bioavailable.
A Ghassemian +44 more
core +1 more source
Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.Complement activation, particularly via the alternative pathway, drives inflammation and organ damage in ANCA‐associated vasculitis. This review highlights mechanistic insights, tissue and biomarker evidence, and clinical implications of targeting the C5a–C5aR1 axis.
Kehinde Sunmboye, Pauline Millan
wiley +1 more source
International Journal of Nanomedicine, 2019 Erik Őrfi,1,2 Tamás Mészáros,1,2 Mark Hennies,3 Tamás Fülöp,1,2 László Dézsi,1,2 Alexander Nardocci,1 László Rosivall,1,2 Péter Hamar,4,5 Barry W Neun,6 Marina A ...
Őrfi E +11 more
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