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Androgen and meibomian gland dysfunction: from basic molecular biology to clinical applications [PDF]
Meibomian gland, the largest sebaceous gland of the body, is responsible for the biosynthesis of lipid layer of the tear film to prevent excessive evaporation.
Li-Xiang Wang, Ying-Ping Deng
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Classic and backdoor pathways of androgen biosynthesis in human sexual development [PDF]
Both genes and hormones regulate human sexual development. Although ovarian hormones are not essential for female external genitalia development, male sexual development requires the action of testicular testosterone and dihydrotestosterone (DHT). DHT is
Hyun Gyung Lee, Chan Jong Kim
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Firing patterns of gonadotropin-releasing hormone neurons are sculpted by their biologic state [PDF]
Gonadotropin-releasing hormone (GnRH) neurons form the final pathway for the central neuronal control of fertility. GnRH is released in pulses that vary in frequency in females, helping drive hormonal changes of the reproductive cycle.
Jonathon Penix+4 more
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Androgen regulation of the androgen receptor coregulators [PDF]
Abstract Background The critical role of the androgen receptor (AR) in the development of prostate cancer is well recognized. The transcriptional activity of AR is partly regulated by coregulatory proteins. It has been suggested that these coregulators could also be important in the progression of prostate cancer. The
Urbanucci, Alfonso+4 more
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Prevalence of Microalbuminuria and Dyslipidemia in Polycystic Ovarian Disease Patients [PDF]
Introduction: Polycystic Ovarian Disease (PCOD) is the most common hormonal disorder in women. PCOD is associated with an increase in subclinical atherosclerotic disease and endothelial dysfunction.
Sasmita Mishra+4 more
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: Anogenital distance (AGD) is a moderately heritable trait that can be measured at a young age that may provide an opportunity to indirectly select for improved fertility in dairy cattle.
M.A. Stephen+7 more
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Updates on androgen replacement therapy and lower urinary tract symptoms: a narrative review
Lower urinary tract symptoms (LUTS) are caused by higher tension at the bladder neck level (due to fibrosis or stiffness) or benign prostatic hyperplasia, which causes static obstruction of the bladder outlet. Both forms cause a group of symptoms such as
Raed M. Al-Zoubi+6 more
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Rats infected with the protozoan Toxoplasma gondii exhibit a reduced aversion to cat odor. This behavioral change is thought to increase trophic transmission of the parasite. Infected male rats also show a greater testicular synthesis of testosterone and
Dhiraj Kumar Singh+3 more
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Androgens and the breast [PDF]
Androgens have important physiological effects in women while at the same time they may be implicated in breast cancer pathologies. However, data on the effects of androgens on mammary epithelial proliferation and/or breast cancer incidence are not in full agreement.
Carolyn A. Bondy+2 more
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