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Testicular descent occurs in two consecutive stages: the transabdominal stage and the inguinoscrotal stage. Androgens play a crucial role in the second stage by influencing the development of the gubernaculum, a structure that pulls the testis into the ...
Zhi-Yi Zhao +5 more
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: Anogenital distance (AGD) is a moderately heritable trait that can be measured at a young age that may provide an opportunity to indirectly select for improved fertility in dairy cattle.
M.A. Stephen +7 more
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Hair Loss and Androgen’s Role in the Era of COVID-19 [PDF]
The new coronavirus (SARS-COV2), which causes coronavirus illness, has expanded globally, impacting millions of individuals. In comparison to female patients, males have a higher prevalence, morbidity, and death rate from this condition, according to ...
Ramadan S. Hussein
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Dysregulated synaptic plasticity is a key feature of neurodevelopmental disorders, including autism. This study investigated whether Fragile X mental retardation protein (FMRP), a selective RNA-binding protein that regulates synaptic protein expression ...
Huan Chen +29 more
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Role of sex and sex hormones in PD-L1 expression in NSCLC: clinical and therapeutic implications
Currently, immunotherapy based on PD-1/PD-L1 pathway blockade has improved survival of non-small cell lung cancer (NSCLC) patients. However, differential responses have been observed by sex, where men appear to respond better than women.
Vianey Rodriguez-Lara +7 more
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Classic and backdoor pathways of androgen biosynthesis in human sexual development [PDF]
Both genes and hormones regulate human sexual development. Although ovarian hormones are not essential for female external genitalia development, male sexual development requires the action of testicular testosterone and dihydrotestosterone (DHT). DHT is
Hyun Gyung Lee, Chan Jong Kim
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We aimed to investigate the relationship between testosterone (T) levels and pregnancy outcomes in patients with tubal or male infertility at different times during in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) cycles.
Zhiyan Chen +3 more
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The role of androgen therapy in acquired aplastic anemia and other bone marrow failure syndromes
Bone marrow failure syndromes are a heterogeneous group of diseases. With the major advancements in diagnostic tools and sequencing techniques, these diseases may be better classified and therapies may be further tailored.
Momen Nassani +12 more
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Prevalence of Microalbuminuria and Dyslipidemia in Polycystic Ovarian Disease Patients [PDF]
Introduction: Polycystic Ovarian Disease (PCOD) is the most common hormonal disorder in women. PCOD is associated with an increase in subclinical atherosclerotic disease and endothelial dysfunction.
Sasmita Mishra +4 more
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Sleep debt is becoming a better acknowledged cause of physiological stress and neurobehavioral deficits with major public-health concerns. We investigated whether exposure to blue light during daytime could be an efficient countermeasure to limit sleep ...
Brice Faraut +19 more
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