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Androgens and the Thymus*

Endocrinology, 1981
Tritiated dihydrotestosterone ([3H]DHT) binds with high affinity to a single class of limited capacity sites in cytoplasmic preparations from rat and mouse thymus glands. The affinity of these bindings sites for [3H]DHT (Kd at 4 C, 1 nM) and their specificity [methyltrienolone (R1881) greater than DHT greater than testosterone much greater than ...
Paul Pearce   +2 more
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Androgens and Anti-androgen Therapy

Archives of Dermatology, 1984
One's first thoughts about a book on androgens and antiandrogens would likely be that it would contain some reference to the skin and that much of the text would be devoted to discussions on hormones and their relevance to other organ systems. Actually, that is not the case here.
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Androgens and Androgen Receptor in Dermatology

2002
In addition to male sexual development and maturation, androgens also mediate sebum secretion and hair growth. The effect of androgens is mainly through their binding to the androgen receptor (AR) which is a nuclear receptor superfamily member. These androgen-AR complexes then enhance their target genes’ expression by binding to response elements in ...
Uno Hideo   +17 more
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Androgens in preeclampsia

American Journal of Obstetrics and Gynecology, 1999
The purpose of the study was to determine whether maternal serum levels of androgens, especially testosterone, are higher in patients with preeclampsia than in matched normotensive control subjects.Serum testosterone, dehydroepiandrosterone sulfate, sex hormone binding globulin, and estradiol levels were measured in 16 subjects in the third trimester ...
Richard Leach   +4 more
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Androgens

2013
Testosterone is the principal circulating androgen in men, secreted almost entirely by the testes. The effects of testosterone on bone in men are therefore best observed when they are deficient in testosterone and then replaced with testosterone. The effects of physiologic concentrations of testosterone in men, as observed in these situations, are ...
Peter J. Snyder, Mona Al Mukaddam
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Androgens and exercise

Medicine & Science in Sports & Exercise, 1975
In this presentation several of the reasons why androgenic hormones might be responsible for some of the effects of physical training and for some of the differences among individuals in athletic ability have been outlined. It seems apparent that minimal amounts of androgen are necessary to produce the normal differences between males and females in ...
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Androgens and Puberty

Best Practice & Research Clinical Endocrinology & Metabolism, 2002
Puberty is associated with an increasing production of androgenic steroids. Adrenal androgen formation, termed adrenarche, may precede gonadal testosterone synthesis. Both adrenal and gonadal androgens exert their biological effects via the androgen receptor, a nuclear transcription factor modulating a specific transcription regulation of largely ...
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Androgens

1987
Publisher Summary The endocrine physiology of the male and the interplay of the several hormones associated with sex determination, fetal development, and, following birth, growth and sexual maturation. The hormones of masculinity are comprised of the gonadotropins, luteinizing hormone and follicle-stimulating hormone, produced by the anterior ...
Anthony W. Norman, Gerald Litwack
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Androgens and alopecia

Molecular and Cellular Endocrinology, 2002
Androgens have profound effects on scalp and body hair in humans. Scalp hair grows constitutively in the absence of androgens, while body hair growth is dependent on the action of androgens. Androgenetic alopecia, referred to as male pattern hair loss (MPHL) in men and female pattern hair loss (FPHL) in women, is due to the progressive miniaturization ...
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Androgens and Erythropoiesis

New England Journal of Medicine, 1973
SINCE early investigations exploring the role of sex hormones on the red cell, hemoglobin and hematocrit,1 , 2 numerous reports have now firmly established that androgens stimulate erythropoiesis.
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