Results 1 to 10 of about 169,598 (149)

Androgen and meibomian gland dysfunction: from basic molecular biology to clinical applications [PDF]

open access: yesInternational Journal of Ophthalmology, 2021
Meibomian gland, the largest sebaceous gland of the body, is responsible for the biosynthesis of lipid layer of the tear film to prevent excessive evaporation.
Li-Xiang Wang, Ying-Ping Deng
doaj   +1 more source

Classic and backdoor pathways of androgen biosynthesis in human sexual development [PDF]

open access: yesAnnals of Pediatric Endocrinology & Metabolism, 2022
Both genes and hormones regulate human sexual development. Although ovarian hormones are not essential for female external genitalia development, male sexual development requires the action of testicular testosterone and dihydrotestosterone (DHT). DHT is
Hyun Gyung Lee, Chan Jong Kim
doaj   +1 more source

Research Progress of Androgen/Androgen Receptor Signaling Pathway in Hepatocellular Carcinoma

open access: yesZhongliu Fangzhi Yanjiu, 2023
Hepatocellular carcinoma (HCC) is a kind of primary liver cancer with a high mortality rate. In China, the incidence ratio in males to females with HCC is 2:1–5:1.
WANG Ruihua   +4 more
doaj   +1 more source

Firing patterns of gonadotropin-releasing hormone neurons are sculpted by their biologic state [PDF]

open access: yesRoyal Society Open Science, 2020
Gonadotropin-releasing hormone (GnRH) neurons form the final pathway for the central neuronal control of fertility. GnRH is released in pulses that vary in frequency in females, helping drive hormonal changes of the reproductive cycle.
Jonathon Penix   +4 more
doaj   +1 more source

Prevalence of Microalbuminuria and Dyslipidemia in Polycystic Ovarian Disease Patients [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
Introduction: Polycystic Ovarian Disease (PCOD) is the most common hormonal disorder in women. PCOD is associated with an increase in subclinical atherosclerotic disease and endothelial dysfunction.
Sasmita Mishra   +4 more
doaj   +1 more source

Genome-wide association study of anogenital distance and its (co)variances with fertility in growing and lactating Holstein-Friesian dairy cattle

open access: yesJournal of Dairy Science, 2023
: Anogenital distance (AGD) is a moderately heritable trait that can be measured at a young age that may provide an opportunity to indirectly select for improved fertility in dairy cattle.
M.A. Stephen   +7 more
doaj   +1 more source

Updates on androgen replacement therapy and lower urinary tract symptoms: a narrative review

open access: yesThe Aging Male, 2022
Lower urinary tract symptoms (LUTS) are caused by higher tension at the bladder neck level (due to fibrosis or stiffness) or benign prostatic hyperplasia, which causes static obstruction of the bladder outlet. Both forms cause a group of symptoms such as
Raed M. Al-Zoubi   +6 more
doaj   +1 more source

Advances in genetics: widening our understanding of prostate cancer [version 1; referees: 2 approved]

open access: yesF1000Research, 2016
Prostate cancer is a leading cause of cancer-related death in Western men. Our understanding of the genetic alterations associated with disease predisposition, development, progression, and therapy response is rapidly improving, at least in part, owing ...
Angela C. Pine   +3 more
doaj   +1 more source

Testosterone Acts Within the Medial Amygdala of Rats to Reduce Innate Fear to Predator Odor Akin to the Effects of Toxoplasma gondii Infection

open access: yesFrontiers in Psychiatry, 2020
Rats infected with the protozoan Toxoplasma gondii exhibit a reduced aversion to cat odor. This behavioral change is thought to increase trophic transmission of the parasite. Infected male rats also show a greater testicular synthesis of testosterone and
Dhiraj Kumar Singh   +3 more
doaj   +1 more source

Behavioral analysis of genetically modified mice indicates essential roles of neurosteroidal estrogen

open access: yesFrontiers in Endocrinology, 2011
Brain aromatase is expressed only in the nerve cells of specific brain regions with a transient peak at the neonatal period when sexual behaviors become organized. Aromatase knockout (ArKO) mouse, generated to give light on the physiological functions of
Nobuhiro eHarada   +2 more
doaj   +1 more source

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