Results 1 to 10 of about 346,728 (197)

Association of Insulin Resistance and Elevated Androgen Levels with Polycystic Ovarian Syndrome (PCOS): A Review of Literature

Journal of Healthcare Engineering, 2022
The polycystic ovary syndrome (PCOS) is the disease featured by elevated levels of androgens, ovulatory dysfunction, and morphological abnormalities. At reproductive stage of women, the rate of PCOS occurrence is measured as 6–10% and the prevalence rate
Yalan Xu, J. Qiao
semanticscholar   +1 more source

Genome-wide association study of anogenital distance and its (co)variances with fertility in growing and lactating Holstein-Friesian dairy cattle

Journal of Dairy Science, 2023
: Anogenital distance (AGD) is a moderately heritable trait that can be measured at a young age that may provide an opportunity to indirectly select for improved fertility in dairy cattle.
M.A. Stephen, C.R. Burke, N. Steele, J.E. Pryce, S. Meier, P.R. Amer, C.V.C. Phyn, D.J. Garrick   +7 more
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Hair Loss and Androgen’s Role in the Era of COVID-19 [PDF]

International Journal of Biomedicine, 2022
The new coronavirus (SARS-COV2), which causes coronavirus illness, has expanded globally, impacting millions of individuals. In comparison to female patients, males have a higher prevalence, morbidity, and death rate from this condition, according to ...
Ramadan S. Hussein
doaj   +1 more source

Fragile X Mental Retardation Protein Mediates the Effects of Androgen on Hippocampal PSD95 Expression and Dendritic Spines Density/Morphology and Autism-Like Behaviors Through miR-125a

Frontiers in Cellular Neuroscience, 2022
Dysregulated synaptic plasticity is a key feature of neurodevelopmental disorders, including autism. This study investigated whether Fragile X mental retardation protein (FMRP), a selective RNA-binding protein that regulates synaptic protein expression ...
Huan Chen, Huan Chen, Dan Qiao, Dan Qiao, Chang Wang, Chang Wang, Chang Wang, Bohan Zhang, Bohan Zhang, Zhao Wang, Zhao Wang, Longmei Tang, Yibo Wang, Ran Zhang, Yizhou Zhang, Yizhou Zhang, Yizhou Zhang, Leigang Song, Leigang Song, Hongchun Zuo, Hongchun Zuo, Fangzhen Guo, Fangzhen Guo, Xia Wang, Sha Li, Sha Li, Sha Li, Huixian Cui, Huixian Cui, Huixian Cui   +29 more
doaj   +1 more source

Role of sex and sex hormones in PD-L1 expression in NSCLC: clinical and therapeutic implications

Frontiers in Oncology, 2023
Currently, immunotherapy based on PD-1/PD-L1 pathway blockade has improved survival of non-small cell lung cancer (NSCLC) patients. However, differential responses have been observed by sex, where men appear to respond better than women.
Vianey Rodriguez-Lara, Giovanny Soca-Chafre, Maria Rosa Avila-Costa, Juan Jose Juarez-Vignon Whaley, Jeronimo Rafael Rodriguez-Cid, José Luis Ordoñez-Librado, Emma Rodriguez-Maldonado, Nallely A. Heredia-Jara   +7 more
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Androgen Receptor Signaling in Prostate Cancer and Therapeutic Strategies

Cancers, 2021
Simple Summary Early-stage and castration-sensitive prostate cancer (PCa) growth is solely mediated by androgen signaling pathways. AR signaling inhibitors (ARSIs) have significantly improved clinical outcomes among men with PCa.
Aasems Jacob, Rishi Raj, Derek B. Allison, Zin W. Myint   +3 more
semanticscholar   +1 more source

Classic and backdoor pathways of androgen biosynthesis in human sexual development [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2022
Both genes and hormones regulate human sexual development. Although ovarian hormones are not essential for female external genitalia development, male sexual development requires the action of testicular testosterone and dihydrotestosterone (DHT). DHT is
Hyun Gyung Lee, Chan Jong Kim
doaj   +1 more source

A Proper Increasing in the Testosterone Level May Be Associated With Better Pregnancy Outcomes for Patients With Tubal or Male Infertility During in vitro Fertilization/Intracytoplasmic Sperm Injection

Frontiers in Physiology, 2021
We aimed to investigate the relationship between testosterone (T) levels and pregnancy outcomes in patients with tubal or male infertility at different times during in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) cycles.
Zhiyan Chen, Duoduo Zhang, Zhengyi Sun, Qi Yu   +3 more
doaj   +1 more source

The role of androgen therapy in acquired aplastic anemia and other bone marrow failure syndromes

Frontiers in Oncology, 2023
Bone marrow failure syndromes are a heterogeneous group of diseases. With the major advancements in diagnostic tools and sequencing techniques, these diseases may be better classified and therapies may be further tailored.
Momen Nassani, Riad El Fakih, Jakob Passweg, Simone Cesaro, Hazzaa Alzahrani, Ali Alahmari, Carmem Bonfim, Raheel Iftikhar, Amal Albeihany, Constantijn Halkes, Syed Osman Ahmed, Carlo Dufour, Mahmoud Aljurf   +12 more
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Androgen Receptor Signaling Pathway in Prostate Cancer: From Genetics to Clinical Applications

Cells, 2020
Around 80–90% of prostate cancer (PCa) cases are dependent on androgens at initial diagnosis; hence, androgen ablation therapy directed toward a reduction in serum androgens and the inhibition of androgen receptor (AR) is generally the first therapy ...
G. Aurilio, A. Cimadamore, R. Mazzucchelli, A. López-Beltran, E. Verri, M. Scarpelli, F. Massari, Liang Cheng, M. Santoni, R. Montironi   +9 more
semanticscholar   +1 more source