WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics [PDF]
Prostate cancer cells with stem cell characteristics were identified in human prostate cancer cell lines by their ability to form from single cells self-renewing prostaspheres in non-adherent cultures.
A de la Taille+82 more
core +1 more source
Supplemental Digital Content is available in the text. Androgen deprivation therapy is a cornerstone of prostate cancer treatment. Pharmacological androgen deprivation includes gonadotropin-releasing hormone agonism and antagonism, androgen receptor ...
Jiun-Ruey Hu+8 more
semanticscholar +1 more source
Spermatogenesis and sertoli cell activity in mice lacking Sertoli cell receptors for follicle stimulating hormone and androgen [PDF]
Spermatogenesis in the adult male depends on the action of FSH and androgen. Ablation of either hormone has deleterious effects on Sertoli cell function and the progression of germ cells through spermatogenesis.
A. Monteiro+63 more
core +2 more sources
Androgens and Hypertension in Men and Women: a Unifying View. [PDF]
This review was designed to revaluate the androgen role on the mechanisms of hypertension and cardiovascular risks in both men and women. Sex steroids are involved in the regulation of blood pressure, but pathophysiological mechanism is not well ...
Carmina, E. 4.+4 more
core +1 more source
Overexpression of Androgen, Oestrogen and Progesterone Receptors in Skin Lesions of Becker’s Naevus
Becker’s naevus is androgen-dependent. The aim of this study was to investigate whether oestrogen and progesterone receptors are involved in this disorder.
Ping Sheng+6 more
doaj +1 more source
Transcriptional regulation of prostate kallikrein-like genes by androgen. [PDF]
Using gene-specific synthetic oligonucleotides the expression and regulation of kallikrein-like genes in the human prostatic cancer cell line LNCaP were studied.
Fittler, Friedrich+2 more
core +1 more source
Role of Androgen Receptor in Prostate Cancer: A Review
Androgen receptor (AR) is a steroid receptor transcriptional factor for testosterone and dihydrotestosterone consisting of four main domains, the N-terminal domain, DNA-binding domain, hinge region, and ligand-binding domain.
K. Fujita, N. Nonomura
semanticscholar +1 more source
Regulatory effect of gut microbes on blood pressure
The interaction between gut microbiota and hypertension, the genera which affect the blood pressure in taxonomic level, and the commonly used treatments to hypertension based on the gut microbes were summarized in this review. The increases of Lactobacillus, etc.
Dong Yan+6 more
wiley +1 more source
Factors that influence the androgen receptor cistrome in benign and malignant prostate cells
The androgen receptor (AR) plays key roles in the development of prostate tissue and the development and progression of prostate cancer (PC). AR guides cytodifferentiation and homeostasis in benign luminal epithelial cells; however, in PC, AR instead ...
Ben T. Copeland+3 more
doaj +1 more source
The effect of different types of hepatic injury on the estrogen and androgen receptor activity of liver [PDF]
Mammalian liver contains receptors for both estrogens and androgens. Hepatic regeneration after partial hepatectomy in male rats is associated with a loss of certain male-specific hepatic characteristics.
Aten R. F.+24 more
core +1 more source