Results 31 to 40 of about 310,378 (283)
Androgen insensitivity syndrome.
Baillière's Clinical Endocrinology and Metabolism, 2019 In a relatively short period of time, understanding of the fundamental causes of androgen insensitivity syndromes has improved dramatically. This has been brought about by the combination of several disciplines, including endocrinology, genetics ...
H. Scharnagl +169 more
semanticscholar +1 more source
Androgen Receptor Signaling Pathway in Prostate Cancer: From Genetics to Clinical Applications
Cells, 2020 Around 80–90% of prostate cancer (PCa) cases are dependent on androgens at initial diagnosis; hence, androgen ablation therapy directed toward a reduction in serum androgens and the inhibition of androgen receptor (AR) is generally the first therapy ...
G. Aurilio +9 more
semanticscholar +1 more source
Journal of Clinical Endocrinology and Metabolism, 2010 OBJECTIVE Our objective was to update the guidelines for the evaluation and treatment of androgen deficiency syndromes in adult men published previously in 2006.
S. Bhasin +6 more
semanticscholar +1 more source
A potential biomarker of androgen exposure in European bullhead (Cottus sp.) kidney [PDF]
Fish Physiology and Biochemistry 39, 3 (2013) 573-580, 2014 The aim of this study was to identify a signal that could be used as an androgen exposure indicator in the European bullhead (Cottus sp.). For this purpose, the ultra-structure of the kidney was characterized to identify normal structure of this organ, and histological changes previously described in the kidney of breeding male bullheads were ...
arxiv +1 more source
Arteriosclerosis, Thrombosis and Vascular Biology, 2020 Supplemental Digital Content is available in the text. Androgen deprivation therapy is a cornerstone of prostate cancer treatment. Pharmacological androgen deprivation includes gonadotropin-releasing hormone agonism and antagonism, androgen receptor ...
Jiun-Ruey Hu +8 more
semanticscholar +1 more source
Overexpression of Androgen, Oestrogen and Progesterone Receptors in Skin Lesions of Becker’s Naevus
Acta Dermato-Venereologica, 2018 Becker’s naevus is androgen-dependent. The aim of this study was to investigate whether oestrogen and progesterone receptors are involved in this disorder.
Ping Sheng +6 more
doaj +1 more source
Role of Androgen Receptor in Prostate Cancer: A Review
The World Journal of Men's Health, 2018 Androgen receptor (AR) is a steroid receptor transcriptional factor for testosterone and dihydrotestosterone consisting of four main domains, the N-terminal domain, DNA-binding domain, hinge region, and ligand-binding domain.
K. Fujita, N. Nonomura
semanticscholar +1 more source
Factors that influence the androgen receptor cistrome in benign and malignant prostate cells
Molecular Oncology, 2019 The androgen receptor (AR) plays key roles in the development of prostate tissue and the development and progression of prostate cancer (PC). AR guides cytodifferentiation and homeostasis in benign luminal epithelial cells; however, in PC, AR instead ...
Ben T. Copeland +3 more
doaj +1 more source
Androgen-Induced Immunosuppression
Frontiers in Immunology, 2018 In addition to determining biological sex, sex hormones are known to influence health and disease via regulation of immune cell activities and modulation of target-organ susceptibility to immune-mediated damage.
M. G. Gubbels Bupp, T. Jorgensen
semanticscholar +1 more source
A STUDY OF THE ANDROGENIC ACTIVITY OF ANTI-ANDROGEN
Folia Endocrinologica Japonica, 1990 To investigate the androgenic activity of steroidal and nonsteroidal anti-androgens, the effect of several compounds on some parameters as an androgenic activity was measured in the ventral prostate (VP) and seminal vesicle gland (SV) of castrated male rats.
Osamu Takahashi +7 more
openaire +4 more sources