Results 31 to 40 of about 389,574 (340)

Updates on androgen replacement therapy and lower urinary tract symptoms: a narrative review

The Aging Male, 2022
Lower urinary tract symptoms (LUTS) are caused by higher tension at the bladder neck level (due to fibrosis or stiffness) or benign prostatic hyperplasia, which causes static obstruction of the bladder outlet. Both forms cause a group of symptoms such as
Raed M. Al-Zoubi, Mustafa Alwani, Omar M. Aboumarzouk, Mai Elaarag, Ahmad R. Al-Qudimat, Laxmi Ojha, Aksam Yassin   +6 more
doaj   +1 more source

International study into the use of intermittent hormone therapy in the treatment of carcinoma of the prostate : A meta-analysis of 1446 patients [PDF]

, 2007
OBJECTIVE: To review pooled phase II data to identify features of different regimens of intermittent hormone therapy (IHT), developed to reduce the morbidity of treating metastatic prostate cancer, and which carries a theoretical advantage of delaying ...
Cuzick, Jack, Goldenberg, S. Larry, Oliver, Tim, Prowse, David M., Shaw, Greg L., Spry, Nigel A., Wilson, Peter   +6 more
core   +1 more source

Animal models of polycystic ovary syndrome: A review of hormone‐induced rodent models focused on hypothalamus‐pituitary‐ovary axis and neuropeptides

Reproductive Medicine and Biology, 2019
Background Polycystic ovary syndrome (PCOS) is a common endocrine disorder among women of reproductive age and a major cause of infertility; however, the pathophysiology of this syndrome is not fully understood.
Satoko Osuka, Natsuki Nakanishi, Tomohiko Murase, Tomoko Nakamura, Maki Goto, Akira Iwase, Fumitaka Kikkawa   +6 more
doaj   +1 more source

Testosterone Acts Within the Medial Amygdala of Rats to Reduce Innate Fear to Predator Odor Akin to the Effects of Toxoplasma gondii Infection

Frontiers in Psychiatry, 2020
Rats infected with the protozoan Toxoplasma gondii exhibit a reduced aversion to cat odor. This behavioral change is thought to increase trophic transmission of the parasite. Infected male rats also show a greater testicular synthesis of testosterone and
Dhiraj Kumar Singh, Shantala Arundathi Hari Dass, Samira Abdulai-Saiku, Ajai Vyas   +3 more
doaj   +1 more source

Divergent Associations Between Serum Androgens and Ovarian Reserve Markers Revealed in Patients With Polycystic Ovary Syndrome

Frontiers in Endocrinology, 2022
BackgroundThe role of excess androgen in ovarian reserve remains unclear in patients with polycystic ovary syndrome (PCOS). Our study highlights the associations of serum androgen levels and ovarian reserve markers in PCOS and non-PCOS women ...
Youran Li, Youran Li, Yanhong Zhai, Yanhong Zhai, Lin Li, Yifan Lu, Yifan Lu, Shaofei Su, Ying Liu, Ying Liu, Zhengwen Xu, Zhengwen Xu, Mingwei Xin, Qiaoli Zhang, Zheng Cao, Zheng Cao   +15 more
doaj   +1 more source

Towards Personalized Prostate Cancer Therapy Using Delta-Reachability Analysis [PDF]

, 2015
Recent clinical studies suggest that the efficacy of hormone therapy for prostate cancer depends on the characteristics of individual patients. In this paper, we develop a computational framework for identifying patient-specific androgen ablation therapy
Biere A., Bogomolov S., Bruchovsky N., Chen X., Cimatti A., Frehse G., Gao S., Palaniappan S. K.   +7 more
core   +1 more source

Four novel mutations identification in 17 beta-hydroxysteroid dehydrogenase-3 deficiency and our clinical experience: possible benefits of early treatment

Frontiers in Endocrinology
IntroductionIndividuals with 17-beta-hydroxysteroid dehydrogenase type 3 (17β-HSD3) deficiency face a multitude of challenges, primarily concerning genital appearance, potential malignancy risks, and fertility issues. This study reports our findings from
Yunpeng Wang, Yunpeng Wang, Yunpeng Wang, Yunpeng Wang, Yu Xu, Yu Xu, Yu Xu, Huijiao Zhang, Huijiao Zhang, Danyang Yin, Yiming Pan, Xiwen He, Xiwen He, Shuaiting Li, Zhi Cheng, Gaohui Zhu, Gaohui Zhu, Ting Zhao, Ting Zhao, Huizhe Huang, Min Zhu, Min Zhu, Min Zhu   +22 more
doaj   +1 more source

Low Serum Dehydroepiandrosterone Is Associated With Diabetic Kidney Disease in Men With Type 2 Diabetes Mellitus

Frontiers in Endocrinology, 2022
BackgroundThe associations of dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) with diabetic kidney disease (DKD) remained unclear. Thus, this cross-sectional study aimed to explore the associations of DHEA and DHEAS with the risk
Xinxin Zhang, Jinfeng Xiao, Xin Li, Jingqiu Cui, Kunling Wang, Qing He, Ming Liu, Ming Liu, Ming Liu   +8 more
doaj   +1 more source

Androgen receptor phosphorylation at serine 515 by Cdk1 predicts biochemical relapse in prostate cancer patients [PDF]

, 2013
<br>Background:Prostate cancer cell growth is dependent upon androgen receptor (AR) activation, which is regulated by specific kinases. The aim of the current study is to establish if AR phosphorylation by Cdk1 or ERK1/2 is of prognostic ...
BV Kallakury, C E Adams, C Tannahill, D Gioeli, D Gioeli, G Fyffe, GG Kuiper, H Y Leung, H Zong, HY Wong, J Edwards, J Ferlay, J M Willder, JC Obenauer, JS Diallo, K Shigemura, KS McCarty, LA Ponguta, LJ Blok, M A Underwood, M Mistry, M Roach, M Seywright, MS Cookson, NG Anderson, P Chymkowitch, P G Horgan, P McCall, R Mukherjee, RE Bakin, RK Tyagi, S Chen, S Chen, S J Heng, SM Powell, T Kirkegaard, T Ohta, WC Bell, Y Wen, Z Fu, ZX Zhou   +40 more
core   +1 more source

Androgen regulation of the androgen receptor coregulators [PDF]

BMC Cancer, 2008
Abstract Background The critical role of the androgen receptor (AR) in the development of prostate cancer is well recognized. The transcriptional activity of AR is partly regulated by coregulatory proteins. It has been suggested that these coregulators could also be important in the progression of prostate cancer. The
Urbanucci, Alfonso, Waltering, Kati K, Suikki, Hanna E, Helenius, Merja A, Visakorpi, Tapio   +4 more
openaire   +4 more sources