Results 31 to 40 of about 346,728 (197)

Testosterone Acts Within the Medial Amygdala of Rats to Reduce Innate Fear to Predator Odor Akin to the Effects of Toxoplasma gondii Infection

Frontiers in Psychiatry, 2020
Rats infected with the protozoan Toxoplasma gondii exhibit a reduced aversion to cat odor. This behavioral change is thought to increase trophic transmission of the parasite. Infected male rats also show a greater testicular synthesis of testosterone and
Dhiraj Kumar Singh, Shantala Arundathi Hari Dass, Samira Abdulai-Saiku, Ajai Vyas   +3 more
doaj   +1 more source

Divergent Associations Between Serum Androgens and Ovarian Reserve Markers Revealed in Patients With Polycystic Ovary Syndrome

Frontiers in Endocrinology, 2022
BackgroundThe role of excess androgen in ovarian reserve remains unclear in patients with polycystic ovary syndrome (PCOS). Our study highlights the associations of serum androgen levels and ovarian reserve markers in PCOS and non-PCOS women ...
Youran Li, Youran Li, Yanhong Zhai, Yanhong Zhai, Lin Li, Yifan Lu, Yifan Lu, Shaofei Su, Ying Liu, Ying Liu, Zhengwen Xu, Zhengwen Xu, Mingwei Xin, Qiaoli Zhang, Zheng Cao, Zheng Cao   +15 more
doaj   +1 more source

Four novel mutations identification in 17 beta-hydroxysteroid dehydrogenase-3 deficiency and our clinical experience: possible benefits of early treatment

Frontiers in Endocrinology
IntroductionIndividuals with 17-beta-hydroxysteroid dehydrogenase type 3 (17β-HSD3) deficiency face a multitude of challenges, primarily concerning genital appearance, potential malignancy risks, and fertility issues. This study reports our findings from
Yunpeng Wang, Yunpeng Wang, Yunpeng Wang, Yunpeng Wang, Yu Xu, Yu Xu, Yu Xu, Huijiao Zhang, Huijiao Zhang, Danyang Yin, Yiming Pan, Xiwen He, Xiwen He, Shuaiting Li, Zhi Cheng, Gaohui Zhu, Gaohui Zhu, Ting Zhao, Ting Zhao, Huizhe Huang, Min Zhu, Min Zhu, Min Zhu   +22 more
doaj   +1 more source

Low Serum Dehydroepiandrosterone Is Associated With Diabetic Kidney Disease in Men With Type 2 Diabetes Mellitus

Frontiers in Endocrinology, 2022
BackgroundThe associations of dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) with diabetic kidney disease (DKD) remained unclear. Thus, this cross-sectional study aimed to explore the associations of DHEA and DHEAS with the risk
Xinxin Zhang, Jinfeng Xiao, Xin Li, Jingqiu Cui, Kunling Wang, Qing He, Ming Liu, Ming Liu, Ming Liu   +8 more
doaj   +1 more source

Androgen Receptor Signaling in the Development of Castration-Resistant Prostate Cancer

Frontiers in Oncology, 2019
Most prostate cancers are androgen-sensitive malignancies whose growths depend on the transcriptional activity of the androgen receptor (AR). In the 1940s, Charles Huggins demonstrated that the surgical removal of testes in men can result in a dramatic ...
Q. Feng, B. He
semanticscholar   +1 more source

The Impact of TRPM8 on Prostate Cancer Transcriptomic Dynamics

Cells
Prostate cancer (PC) remains a significant health challenge, with androgen receptor (AR) signaling playing a pivotal role in its progression. This study investigates the expression and functional implications of the transient receptor potential ...
Swapna Asuthkar, Susovon Bayen, Erick B. Saldes, Benny Tom, Jai Velpula, Sarangi Siddharth, Timothy E. Koeltzow, Donald J. Vander Griend   +7 more
doaj   +1 more source

Sex Disparities in Asthma Development and Clinical Outcomes: Implications for Treatment Strategies

Journal of Asthma and Allergy, 2022
Guo-Qiang Zhang,1 Saliha Selin Özuygur Ermis,1,2 Madeleine Rådinger,1 Apostolos Bossios,3,4 Hannu Kankaanranta,1,5,6 Bright Nwaru1,7 1Krefting Research Centre, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden ...
Zhang GQ, Özuygur Ermis SS, Rådinger M, Bossios A, Kankaanranta H, Nwaru B   +5 more
doaj  

A unique androgen excess signature in idiopathic intracranial hypertension is linked to cerebrospinal fluid dynamics

JCI Insight, 2019
Idiopathic intracranial hypertension (IIH) is a condition of unknown etiology, characterized by elevated intracranial pressure frequently manifesting with chronic headaches and visual loss.
M. O’Reilly, C. Westgate, C. Hornby, H. Botfield, A. Taylor, K. Markey, J. Mitchell, W. Scotton, S. Mollan, A. Yiangou, C. Jenkinson, L. Gilligan, M. Sherlock, J. Gibney, J. Tomlinson, G. Lavery, D. Hodson, W. Arlt, A. Sinclair   +18 more
semanticscholar   +1 more source

Comparative Study of Anti-Mullerian Hormone and its Correlation with Androgens and Insulin Resistance in Lean and Obese Women with Polycystic Ovary Syndrome

Indian Journal of Endocrinology and Metabolism
Introduction: Anti-Mullerian hormone (AMH) is a key regulator of ovarian folliculogenesis. Obesity, insulin resistance (IR), hyperandrogenism, and gonadotropins have an inconclusive role in the relation and regulation of AMH to polycystic ovarian ...
Sukirti Misra, Jugal V. Gada, Yash V. Chauhan, Sachin S. Rahate, Bhakti D. Karde, Premlata K. Varthakavi, Nikhil M. Bhagwat   +6 more
doaj   +1 more source

Genomic Deletion at 10q23 in Prostate Cancer: More Than PTEN Loss?

Frontiers in Oncology, 2018
The PTEN gene encodes for the phosphatase and tensin homolog; it is a tumor suppressor gene that is among the most frequently inactivated genes throughout the human cancer spectrum. The most recent sequencing approaches have allowed the identification of
Raghavendra Tejo Karthik Poluri, Étienne Audet-Walsh, Étienne Audet-Walsh   +2 more
doaj   +1 more source