Results 41 to 50 of about 346,728 (197)
The Androgen Receptor in Breast Cancer
Frontiers in Endocrinology, 2018 Breast cancer (BC) is a hormone-related tumor. Despite the progress in BC therapy, this disease still remains the most common cancer amongst women around the world. This is likely due to the amazing BC heterogeneity. Accumulating evidence suggests a role
P. Giovannelli +5 more
semanticscholar +1 more source
Androgen-Induced, β-Catenin-Activated Hepatocellular Adenomatosis with Spontaneous External Rupture
DiagnosticsAndrogens have long been recognized as oncogenic agents. They can induce both benign and malignant hepatocellular neoplasms, including hepatocellular adenoma (HCA) and hepatocellular carcinoma, though the underlying mechanisms remain unclear.
Jialing Huang +3 more
doaj +1 more source
Sex Hormones Regulate Innate Immune Cells and Promote Sex Differences in Respiratory Virus Infection
Frontiers in Immunology, 2018 Sex differences in the incidence and severity of respiratory virus infection are widely documented in humans and murine models and correlate with sex biases in numbers and/or functional responses of innate immune cells in homeostasis and lung infection ...
Sapana Kadel +3 more
doaj +1 more source
The Mechanism of Androgen Actions in PCOS Etiology
Medical Science, 2019 Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive-age women. By comprising reproductive, endocrine, metabolic and psychological features—the cause of PCOS is still unknown.
Valentina Rodriguez Paris, M. Bertoldo
semanticscholar +1 more source
Journal of Blood Medicine, 2022 Worachaya Pengthina,1 Pirun Saelue2 1Pharmaceutical Care Training Center, Department of Pharmaceutical Care, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand; 2Clinical Hematology Unit, Division of Internal Medicine, Faculty of Medicine ...
Pengthina W, Saelue P
doaj
Frontiers in Endocrinology, 2018 Nonsyndromic cryptorchidism is a common multifactorial, condition with long-term risks of subfertility and testicular cancer. Revealing the causes of cryptorchidism will likely improve prediction and prevention of adverse outcomes.
Julia S. Barthold, Richard Ivell
doaj +1 more source
Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer
Nature Communications, 2017 Emerging data demonstrate homologous recombination (HR) defects in castration-resistant prostate cancers, rendering these tumours sensitive to PARP inhibition.
M. Asim +29 more
semanticscholar +1 more source
Journal of Health Science and Medical Research (JHSMR), 2021 Objective: To identify the normal reference ranges of serum testosterone and gonadotropins in Thai fertile men, compare these levels among different age groups, and assess their relationships with body mass index (BMI). Material and Methods: One hundred
Thakorn Pruktanakul +4 more
doaj +1 more source
Cells, 2019 Androgens are not only essential for bone development but for the maintenance of bone mass. Therefore, conditions with androgen deficiency, such as male hypogonadism, androgen-insensitive syndromes, and prostate cancer with androgen deprivation therapy ...
Jia-Feng Chen +4 more
semanticscholar +1 more source
Factors that influence the androgen receptor cistrome in benign and malignant prostate cells
Molecular Oncology, 2019 The androgen receptor (AR) plays key roles in the development of prostate tissue and the development and progression of prostate cancer (PC). AR guides cytodifferentiation and homeostasis in benign luminal epithelial cells; however, in PC, AR instead ...
Ben T. Copeland +3 more
doaj +1 more source