Results 41 to 50 of about 310,378 (283)

Efficacy of Oxymetholone in Severe and Nonsevere Acquired Aplastic Anemia: A Propensity Score Matching Analysis

open access: yesJournal of Blood Medicine, 2022
Worachaya Pengthina,1 Pirun Saelue2 1Pharmaceutical Care Training Center, Department of Pharmaceutical Care, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand; 2Clinical Hematology Unit, Division of Internal Medicine, Faculty of Medicine ...
Pengthina W, Saelue P
doaj  

Prevalence of Microalbuminuria and Dyslipidemia in Polycystic Ovarian Disease Patients [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
Introduction: Polycystic Ovarian Disease (PCOD) is the most common hormonal disorder in women. PCOD is associated with an increase in subclinical atherosclerotic disease and endothelial dysfunction.
Sasmita Mishra   +4 more
doaj   +1 more source

Research Progress of Androgen/Androgen Receptor Signaling Pathway in Hepatocellular Carcinoma

open access: yesZhongliu Fangzhi Yanjiu, 2023
Hepatocellular carcinoma (HCC) is a kind of primary liver cancer with a high mortality rate. In China, the incidence ratio in males to females with HCC is 2:1–5:1.
WANG Ruihua   +4 more
doaj   +1 more source

Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistance

open access: yesCommunications Biology, 2018
The androgen receptor is a major driver of prostate cancer and inhibition of its transcriptional activity using competitive antagonists, such as enzalutamide remains a frontline therapy for prostate cancer management.
J. Salami   +10 more
semanticscholar   +1 more source

Testosterone Acts Within the Medial Amygdala of Rats to Reduce Innate Fear to Predator Odor Akin to the Effects of Toxoplasma gondii Infection

open access: yesFrontiers in Psychiatry, 2020
Rats infected with the protozoan Toxoplasma gondii exhibit a reduced aversion to cat odor. This behavioral change is thought to increase trophic transmission of the parasite. Infected male rats also show a greater testicular synthesis of testosterone and
Dhiraj Kumar Singh   +3 more
doaj   +1 more source

The gut microbiota is a major regulator of androgen metabolism in intestinal contents

open access: yesAmerican Journal of Physiology. Endocrinology and Metabolism, 2019
Androgens exert important effects both in androgen-responsive tissues and in the intestinal tract. To determine the impact of the gut microbiota (GM) on intestinal androgen metabolism, we measured unconjugated (free) and glucuronidated androgen levels in
Hannah Colldén   +10 more
semanticscholar   +1 more source

Contextual modulation of social and endocrine correlates of fitness: insights from the life history of a sex changing fish

open access: yesFrontiers in Neuroscience, 2015
Steroid hormones are critical regulators of reproductive life history, and the steroid sensitive traits (morphology, behavior, physiology) associated with particular life history stages can have substantial fitness consequences for an organism. Hormones,
Devaleena S Pradhan   +4 more
doaj   +1 more source

The role of androgen therapy in acquired aplastic anemia and other bone marrow failure syndromes

open access: yesFrontiers in Oncology, 2023
Bone marrow failure syndromes are a heterogeneous group of diseases. With the major advancements in diagnostic tools and sequencing techniques, these diseases may be better classified and therapies may be further tailored.
Momen Nassani   +12 more
doaj   +1 more source

Genomic Deletion at 10q23 in Prostate Cancer: More Than PTEN Loss?

open access: yesFrontiers in Oncology, 2018
The PTEN gene encodes for the phosphatase and tensin homolog; it is a tumor suppressor gene that is among the most frequently inactivated genes throughout the human cancer spectrum. The most recent sequencing approaches have allowed the identification of
Raghavendra Tejo Karthik Poluri   +2 more
doaj   +1 more source

The unique interplay of mitochondrial oxidative phosphorylation (OXPHOS) and immunity and its potential implication for the sex‐ and age‐related morbidity of severe COVID‐19 patients

open access: yesMedComm, 2023
Aged male patients are more vulnerable to severe or critical symptoms of COVID‐19, but the underlying mechanism remains elusive. In this study, we analyzed previously published scRNA‐seq data from a large cohort of COVID‐19 patients, castrated and ...
Yinchuan Li   +11 more
doaj   +1 more source

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