Results 71 to 80 of about 434,055 (399)
Androgen Receptor and Mechanism of Androgen Action
Annals of Medicine, 1993 Androgen receptor is the intracellular protein that mediates biological actions of physiological androgens (testosterone and 5 alpha-dihydrotestosterone). Androgen receptor belongs to a large family of ligand-dependent proteins whose function is to modulate expression of genes and gene networks in a cell- and tissue-specific manner.
Pekka Kallio +3 more
openaire +3 more sources
JCI Insight, 2019 Idiopathic intracranial hypertension (IIH) is a condition of unknown etiology, characterized by elevated intracranial pressure frequently manifesting with chronic headaches and visual loss.
M. O’Reilly +18 more
semanticscholar +1 more source
Role of sex and sex hormones in PD-L1 expression in NSCLC: clinical and therapeutic implications
Frontiers in Oncology, 2023 Currently, immunotherapy based on PD-1/PD-L1 pathway blockade has improved survival of non-small cell lung cancer (NSCLC) patients. However, differential responses have been observed by sex, where men appear to respond better than women.
Vianey Rodriguez-Lara +7 more
doaj +1 more source
Renal Subcapsular xenografing of human fetal external genital tissue - A new model for investigating urethral development. [PDF]
, 2017 In this paper, we introduce our novel renal subcapsular xenograft model for the study of human penile urethral and clitoral development. We grafted fifteen intact fetal penes and clitorides 8-11 weeks fetal age under the renal capsules of gonadectomized ...
Baskin, Laurence +6 more
core +2 more sources
The Androgen Receptor in Breast Cancer
Frontiers in Endocrinology, 2018 Breast cancer (BC) is a hormone-related tumor. Despite the progress in BC therapy, this disease still remains the most common cancer amongst women around the world. This is likely due to the amazing BC heterogeneity. Accumulating evidence suggests a role
P. Giovannelli +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić +31 more
wiley +1 more source
Journal of Health Science and Medical Research (JHSMR), 2021 Objective: To identify the normal reference ranges of serum testosterone and gonadotropins in Thai fertile men, compare these levels among different age groups, and assess their relationships with body mass index (BMI). Material and Methods: One hundred
Thakorn Pruktanakul +4 more
doaj +1 more source
The Nipple-Areola Complex for Criminal Identification [PDF]
, 2019 In digital and multimedia forensics, identification of child sexual offenders based on digital evidence images is highly challenging due to the fact that the offender's face or other obvious characteristics such as tattoos are occluded, covered, or not visible at all. Nevertheless, other naked body parts, e.g., chest are still visible. Some researchers
arxiv +1 more source
Androgenetic alopecia: a review [PDF]
, 2017 Purpose Androgenetic alopecia, commonly known as male pattern baldness, is the most common type of progressive hair loss disorder in men. The aim of this paper is to review recent advances in understanding the pathophysiology and molecular mechanism
Caro, Gemma +7 more
core +1 more source
Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer
Nature Communications, 2017 Emerging data demonstrate homologous recombination (HR) defects in castration-resistant prostate cancers, rendering these tumours sensitive to PARP inhibition.
M. Asim +29 more
semanticscholar +1 more source