Asian Journal of AndrologyTesticular descent occurs in two consecutive stages: the transabdominal stage and the inguinoscrotal stage. Androgens play a crucial role in the second stage by influencing the development of the gubernaculum, a structure that pulls the testis into the ...
Zhi-Yi Zhao +5 more
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The Role of Androgen Receptor Signaling in Ovarian Cancer
Cells, 2019 Emerging evidence has suggested that androgen receptor signaling plays an important role in ovarian cancer outgrowth. Specifically, androgen receptor activation appears to be associated with increased risks of developing ovarian cancer and inducing tumor
Taichi Mizushima, Hiroshi Miyamoto
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LncRNA-Dependent Mechanisms of Androgen Receptor-regulated Gene Activation Programs
Nature, 2013 Although recent studies have indicated roles of long non-coding RNAs (lncRNAs) in physiological aspects of cell-type determination and tissue homeostasis, their potential involvement in regulated gene transcription programs remains rather poorly ...
Liuqing Yang +11 more
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ASC-J9® increases the bladder cancer chemotherapy efficacy via altering the androgen receptor (AR) and NF-κB survival signals [PDF]
, 2019 Chi‐Ping Huang +7 more
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Involvement of IGF-1R-PI3K-AKT-mTOR Pathway in Increased Number of GnRH3 Neurons During Androgen-induced Sex Reversal of the Brain in Female Tilapia [PDF]
, 2021 Akari Oda +7 more
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Krüppel-like factor 8 is a novel androgen receptor co-activator in human prostate cancer [PDF]
, 2012 Hongjiang He +5 more
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The roles of sex hormones in the pathophysiology of age‐related sarcopenia and frailty
Reproductive Medicine and BiologyBackground Sarcopenia is an age‐related condition characterized by a progressive and systemic decline in skeletal muscle mass, quality, and strength. The incidence of sarcopenia contains sex‐specific aspects, indicating the contribution of sex hormones ...
Tatsuya Hosoi +4 more
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Deletion of the Androgen Receptor in Adipose Tissue in Male Mice Elevates Retinol Binding Protein 4 and Reveals Independent Effects on Visceral Fat Mass and on Glucose Homeostasis [PDF]
, 2012 Kerry J. McInnes +5 more
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Clinical, Ovulatory and Histological Effect of a Postnatal Testosterone Treatment in Female Dogs
AnimalsIt has been described in some female mammalian species that postnatal androgenization causes reproductive structural and functional abnormalities. The objective of this study was to describe the clinical, ovulatory and genital effects of postnatal ...
Cynthia Marchetti +4 more
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