Results 31 to 40 of about 25,474 (169)

Conflicting Actions of Inhalational Anesthetics, Neurotoxicity and Neuroprotection, Mediated by the Unfolded Protein Response

, 2020
Preclinical studies have shown that exposure of the developing brain to inhalational anesthetics can cause neurotoxicity. However, other studies have claimed that anesthetics can exert neuroprotective effects.
Mari Komita, Tomohiko Aoe, Hisayo Jin, Hiroshi Kokubun   +3 more
core   +1 more source

How should we monitor pediatric patients with Duchenne muscular dystrophy? -A case report- [PDF]

Korean Journal of Anesthesiology, 2011
Duchenne muscular dystrophy is a hereditary disorder characterized by progressive muscle weakness and contracture, and special care during anesthesia is needed in these patients.
Hyun Ju Jung, Jong Bun Kim, Kyong Shil Im, Jeoung Hyuk Lee, Duk Ju Kim, Sung Ah Cho, Jae Myeong Lee   +6 more
doaj   +1 more source

THE PROTECTIVE EFFECT OF INSULIN AGAINST ISOFLURANE AND SEVOFLURANE INDUCED HEPATOCELLULAR APOPTOSIS [PDF]

Journal of the Egyptian Society of Parasitology, 2018
Several studies deducted that inhalational anesthetics induce apoptosis in human cells. Insulin is believed to have an antiapoptotic action so it is widely used as cardioprotective agent against ischemic reperfusion injuries.
HODA OKASHA, AHMED HELMY, MONA HASSAN, OLFAT HAMMAM, MOHAMED HUSSEIN, MOHAMED MAHER, WAEL EL-SIORY, MOSHIRA SAYED, KHALDA RADWAN   +8 more
doaj   +1 more source

Inhalational Anesthetics Inhibit Neuroglioma Cell Proliferation and Migration via miR-138, -210 and -335

, 2021
Inhalational anesthetics was previously reported to suppress glioma cell malignancy but underlying mechanisms remain unclear. The present study aims to investigate the effects of sevoflurane and desflurane on glioma cell malignancy changes via microRNA ...
Masae Iwasaki, Cong Hu, Atsuhiro Sakamoto, Masashi Ishikawa, Junichi Saito, Qizhe Sun, Hailin Zhao, Daqing Ma   +7 more
core   +1 more source

Low flow anesthesia [PDF]

Serbian Journal of Anesthesia and Intensive Therapy, 2016
Historically, rebreathing anesthesia systems were invented to reduce the consumption of volatile anesthetics and to optimize respiratory gas conditioning. However, the industry is still modifying and optimizing the rebreathing circle systems. Most of the
Honemann Cristian, Rubsam Marie-Luise
doaj   +1 more source

Anesthetics may modulate cancer surgical outcome: a possible role of miRNAs regulation

BMC Anesthesiology, 2021
Background microRNAs (miRNAs) are single-stranded and noncoding RNA molecules that control post-transcriptional gene regulation. miRNAs can be tumor suppressors or oncogenes through various mechanism including cancer cell biology, cell-to-cell ...
Masashi Ishikawa, Masae Iwasaki, Atsuhiro Sakamoto, Daqing Ma   +3 more
doaj   +1 more source

Computational studies on the interactions of inhalational anesthetics with proteins.

, 2010
Despite the widespread clinical use of anesthetics since the 19th century, a clear understanding of the mechanism of anesthetic action has yet to emerge.
Vemparala, Satyavani, Klein, Michael L., Vemparala, S, Domene, C, Klein, ML   +4 more
core   +1 more source

Monitoring early cell damage in physicians who are occupationally exposed to inhalational anesthetics

, 2018
Worldwide, millions of professionals who work in operating rooms are occupationally exposed to inhalational anesthetics. Thus, the potential health effects of the continuous exposure to inhalational anesthetics on individuals in the operating room remain
Golim, Marjorie A. [UNESP], Aun, Aline G. [UNESP], Braz, Leandro G. [UNESP], Braz, José Reinaldo C. [UNESP], Souza, Kátina M. [UNESP], Arruda, Nayara M. [UNESP], Braz, Mariana G. [UNESP], Nogueira, Flávia R. [UNESP]   +7 more
core   +1 more source

Detecting high‐frequency oscillations in real time during epilepsy surgery with neuromorphic hardware validated to predict postoperative seizure outcome

Epilepsia, EarlyView.
Abstract Objective High‐frequency oscillations (HFOs; 250–500 Hz) in electrocorticography (ECoG) are promising biomarkers for delineating the epileptogenic zone during epilepsy surgery. Accurate, intraoperative real‐time detection of HFOs may guide surgical resection to improve seizure outcome.
Jeroen Teurlings, Filippo Costa, Maeike Zijlmans, Maryse A. van ‘t Klooster, Giacomo Indiveri, Niklaus Krayenbühl, Murezi Capaul, Debora Ledergerber, Georgia Ramantani, Johannes Sarnthein   +9 more
wiley   +1 more source

Effects of Ferrostatin‐1 on Vocal Folds in Aging Rats

The Laryngoscope, EarlyView.
Age‐related vocal fold degeneration is associated with oxidative stress, and ferroptosis may contribute to structural changes in aging vocal folds. In this aged rat model, intracordal injection of the antioxidant ferrostatin‐1 attenuated ferroptosis‐related changes and was associated with modulation of collagen accumulation, hyaluronic acid ...
Yong‐Il Cheon, Soo‐Young Bang, Ji Min Kim, Ha‐Nee Kwon, Minhyung Lee, Eui‐Suk Sung, Jin‐Choon Lee, Byung‐Joo Lee, Sung‐Chan Shin   +8 more
wiley   +1 more source