Results 31 to 40 of about 4,829 (188)

A Millimeter‐Scale Implantable Magneto–Mechano–Electric Transducer Based on BTO Piezoelectric Ceramics for Remote Wireless Electrical Stimulation of Injured Sciatic Nerves

Advanced Science, EarlyView.
We report a fully wireless, circuit‐free neural stimulator built on a millimetric magneto‐mechano‐electric (MME) cantilever transducer (3 × 10 × 5 mm) with a barium titanate (BTO) piezoelectric ceramic core. Under low‐frequency alternating magnetic fields, the MME cantilever mechanically oscillates, inducing stress on the BTO element and thereby ...
Yijing Wang, Jingyu Tian, Zhe Xu, Cuiling Zhang, Jingen Wu, Ming Liu, Zhilu Ye, Xiaohui Zhang   +7 more
wiley   +1 more source

Age-Related Effects of Inhalational Anesthetics in B4galnt1-Null and Cuprizone-Treated Mice: Clinically Relevant Insights into Demyelinating Diseases

Current Issues in Molecular Biology
Anesthetics are essential agents that are frequently used in clinical practice to induce a reversible loss of consciousness and sensation by depressing the central nervous system.
Ozana Katarina Tot, Stefan Mrđenović, Vedrana Ivić, Robert Rončević, Jakov Milić, Barbara Viljetić, Marija Heffer   +6 more
doaj   +1 more source

Total Intravenous Anesthesia for Repair of Congenital Diaphragmatic Hernia: A Case Report

Kaohsiung Journal of Medical Sciences, 2004
Congenital diaphragmatic hernia is a cardiopulmonary anomaly that causes severe respiratory disorder. Traditionally, inhalational anesthetics with mechanical hyperventilation, opioids, and muscle relaxants are used in anesthesia for repair surgery.
Hung-Te Hsu, Yin-Lung Chang, Kwong-Leung Yu, Kuang-I Cheng, Chao-Shun Tang   +4 more
doaj   +1 more source

Inhalable ROS‐Responsive Nanospray Activates PPAR‐γ to Restore Macrophage Mitochondrial Homeostasis and Attenuate Radiation‐Induced Lung Injury

Advanced Science, EarlyView.
A nebulized nanoassembly alleviates radiation‐induced lung injury by reprogramming macrophages through coordinated ROS scavenging, NAD+ replenishment, and PPAR‐γ activation. Redox balance, mitochondrial homeostasis, and immune regulation are restored, revealing a microenvironment‐centered strategy for localized radioprotection.
Mingquan Gao, Xudong Yu, Ziqian Shang, Mengyao Tan, Xie Huang, Zaizhi Du, Xiaojiao Wang, Xinrui Yang, Ximei Luo, Weidong Wang, Rong Li, Shenglin Luo   +11 more
wiley   +1 more source

USP30‐Mediated Deubiquitination of PEX5 Suppresses Pexophagy to Drive Tubular Injury in Diabetic Kidney Disease

Advanced Science, EarlyView.
USP30 accumulation in diabetic renal tubular epithelial cells deubiquitinates PEX5, suppresses pexophagy, and drives dysfunctional peroxisome accumulation and tubular injury. USP30 depletion restores PEX5 ubiquitination and pexophagy, improves peroxisomal function, and alleviates tubular damage, highlighting USP30 as a therapeutic target in diabetic ...
Jia Li, Chaoyang Hua, Guangpu Li, Furong Zhai, Jingjing Ren, Shaokang Pan, Qi Feng, Jianguo Wen, Dongwei Liu, Zhangsuo Liu, Jiayu Duan   +10 more
wiley   +1 more source

Outcomes of intravenous and inhalation anesthesia on patients undergoing esophageal cancer surgery: a retrospective observational study

BMC Anesthesiology, 2023
Background Different anesthetics may have opposite effects on the immune system, thus affecting the prognosis of tumor patients. Cell-mediated immunity forms the primary defense against the invasion of tumor cells, so manipulation of the immune system to
Yue Ma, Jie Ren, Zhuo Chen, Jingwen Chen, Ming Wei, Yu Wang, Hong Chen, Liping Wang   +7 more
doaj   +1 more source

Anesthesia and Oncology: Friend or Foe?

Frontiers in Oncology, 2022
Cancer is a leading cause of death, and surgery is an important treatment modality. Laboratory research and retrospective studies have raised the suspicion that the choice of anesthetics for cancer surgery might affect the course of cancerous disease ...
Bigna S. Buddeberg, Bigna S. Buddeberg, Manfred D. Seeberger   +2 more
doaj   +1 more source

Detecting high‐frequency oscillations in real time during epilepsy surgery with neuromorphic hardware validated to predict postoperative seizure outcome

Epilepsia, EarlyView.
Abstract Objective High‐frequency oscillations (HFOs; 250–500 Hz) in electrocorticography (ECoG) are promising biomarkers for delineating the epileptogenic zone during epilepsy surgery. Accurate, intraoperative real‐time detection of HFOs may guide surgical resection to improve seizure outcome.
Jeroen Teurlings, Filippo Costa, Maeike Zijlmans, Maryse A. van ‘t Klooster, Giacomo Indiveri, Niklaus Krayenbühl, Murezi Capaul, Debora Ledergerber, Georgia Ramantani, Johannes Sarnthein   +9 more
wiley   +1 more source

Desflurane - Revisited

Journal of Anaesthesiology Clinical Pharmacology, 2012
The search for an ideal inhalational general anesthetic agent continues. Desflurane, which was recently introduced in the Indian market, possesses favorable pharmacokinetic and pharmacodynamic properties and is closer to the definition of an ideal agent.
Mukul Chandra Kapoor, Mahesh Vakamudi
doaj   +1 more source

A synthetic peptide rescues rat cortical neurons from anesthetic-induced cell death, perturbation of growth and synaptic assembly

Scientific Reports, 2021
Anesthetics are deemed necessary for all major surgical procedures. However, they have also been found to exert neurotoxic effects when tested on various experimental models, but the underlying mechanisms remain unknown.
Fahad Iqbal, Marcus Pehar, Andrew J. Thompson, Urva Azeem, Kiana Jahanbakhsh, Nerea Jimenez-Tellez, Rasha Sabouny, Shadab Batool, Atika Syeda, Jennifer Chow, Pranav Machiraju, Timothy Shutt, Kamran Yusuf, Jane Shearer, Tiffany Rice, Naweed I. Syed   +15 more
doaj   +1 more source