Results 41 to 50 of about 7,950 (224)

Retrospective review of anesthetic and analgesic regimens used in animal research proposals [PDF]

open access: yes, 2019
Pain has a profound effect on an animal’s wellbeing. In Germany, researchers using animals have been legally required to reduce any possible pain, suffering, distress or lasting harm to an absolute minimum since 1972.
Flecknell, Paul, Herrmann, Kathrin
core   +2 more sources

Total Intravenous Anesthesia for Repair of Congenital Diaphragmatic Hernia: A Case Report

open access: yesKaohsiung Journal of Medical Sciences, 2004
Congenital diaphragmatic hernia is a cardiopulmonary anomaly that causes severe respiratory disorder. Traditionally, inhalational anesthetics with mechanical hyperventilation, opioids, and muscle relaxants are used in anesthesia for repair surgery.
Hung-Te Hsu   +4 more
doaj   +1 more source

Anesthesia and Oncology: Friend or Foe?

open access: yesFrontiers in Oncology, 2022
Cancer is a leading cause of death, and surgery is an important treatment modality. Laboratory research and retrospective studies have raised the suspicion that the choice of anesthetics for cancer surgery might affect the course of cancerous disease ...
Bigna S. Buddeberg   +2 more
doaj   +1 more source

Robot‐Assisted Doppler Optical Coherence Tomography for Intraoperative Evaluation of Microvascular Anastomoses

open access: yesAdvanced Intelligent Systems, EarlyView.
This work presents a robot‐assisted Doppler optical coherence tomography system for autonomous, wide‐field intraoperative assessment of microvascular anastomoses. Machine‐vision–guided probe positioning and adaptive scan planning enable three‐dimensional structural and hemodynamic imaging over extended vessel segments.
Xiaochen Li   +10 more
wiley   +1 more source

Age-Related Effects of Inhalational Anesthetics in B4galnt1-Null and Cuprizone-Treated Mice: Clinically Relevant Insights into Demyelinating Diseases

open access: yesCurrent Issues in Molecular Biology
Anesthetics are essential agents that are frequently used in clinical practice to induce a reversible loss of consciousness and sensation by depressing the central nervous system.
Ozana Katarina Tot   +6 more
doaj   +1 more source

How Anesthetic, Analgesic and Other Non-Surgical Techniques During Cancer Surgery Might Affect Postoperative Oncologic Outcomes:A Summary of Current State of Evidence [PDF]

open access: yes, 2019
The question of whether anesthetic, analgesic or other perioperative intervention during cancer resection surgery might influence long-term oncologic outcomes has generated much attention over the past 13 years. A wealth of experimental and observational
Aguirre, Jose A.   +23 more
core   +5 more sources

Outcomes of intravenous and inhalation anesthesia on patients undergoing esophageal cancer surgery: a retrospective observational study

open access: yesBMC Anesthesiology, 2023
Background Different anesthetics may have opposite effects on the immune system, thus affecting the prognosis of tumor patients. Cell-mediated immunity forms the primary defense against the invasion of tumor cells, so manipulation of the immune system to
Yue Ma   +7 more
doaj   +1 more source

Monosynaptic Functional Connectivity in Cerebral Cortex During Wakefulness and Under Graded Levels of Anesthesia [PDF]

open access: yes, 2012
The balance between excitation and inhibition is considered to be of significant importance for neural computation and cognitive function. Excitatory and inhibitory functional connectivity in intact cortical neuronal networks in wakefulness and graded ...
Diba, Kamran   +4 more
core   +3 more sources

EEG Dynamics in Children Before, During and After General Anesthesia

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT Background Age‐specific EEG signatures during anesthesia are described in pediatrics, and perioperative monitoring is increasingly advocated; yet most indices and algorithms derive from adult data and may not generalize to early development. Aims The purpose of this study was to characterize perioperative frontal EEGs in young children younger
Maximilian Markus   +3 more
wiley   +1 more source

A synthetic peptide rescues rat cortical neurons from anesthetic-induced cell death, perturbation of growth and synaptic assembly

open access: yesScientific Reports, 2021
Anesthetics are deemed necessary for all major surgical procedures. However, they have also been found to exert neurotoxic effects when tested on various experimental models, but the underlying mechanisms remain unknown.
Fahad Iqbal   +15 more
doaj   +1 more source

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