The Effect of Conditioned Medium from Angiopoietin-1 Gene-Modified Mesenchymal Stem Cells on Wound Healing in a Diabetic Mouse Model. [PDF]
Deng Q +9 more
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Differential expression of angiogenesis-related genes 'VEGF' and 'angiopoietin-1' in metastatic and EMAST-positive colorectal cancer patients. [PDF]
Torshizi Esfahani A +8 more
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Treatment of vascular dementia in female rats with AV-001, an Angiopoietin-1 mimetic peptide, improves cognitive function. [PDF]
Gao H +9 more
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Expression of Concern: Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression. [PDF]
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[Correlation of Serum Neuron-Specific Enolase, Angiopoietin-1, and Angiopoietin-Like Protein-3 With Disease Severity and Their Prognostic Value in Patients With Cerebral Infarction]. [PDF]
Liu J, Gao H, Liu Y.
europepmc +1 more source
Signaling and Functions of Angiopoietin-1 in Vascular Protection [PDF]
Angiopoietin-1 (Ang1) has powerful vascular protective effects: suppressing plasma leakage, inhibiting vascular inflammation, and preventing endothelial death. Preclinical studies indicate that Ang1 may be therapeutically useful in a number of situations, including treatment of edema, endotoxemia, and transplant arteriosclerosis.
Nicholas Brindle +2 more
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Angiopoietin-1 and Myeloma-Induced Angiogenesis
Leukemia & Lymphoma, 2005Multiple myeloma (MM) is a plasma cell malignancy characterized by an increase of the bone marrow angiogenesis. Angiopoietin-1 (Ang-1) is a critical factor in the regulation of physiological and pathological vessel formation that acts by binding to a specific receptor Tie2 expressed on endothelial cells.
GIULIANI, Nicola +3 more
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ANGIOPOIETIN-1 IN THE TREATMENT OF ISCHEMIA AND SEPSIS
Shock, 2009Angiogenic factors have been the focus of a great deal of research for the treatment of ischemic diseases. Described just more than 10 years ago, angiopoietin 1 (Ang-1) has shown promising results in I/R models. Angiopoietin 1 is essential for both embryonic vasculogenesis and adult angiogenesis.
Nathan M, Novotny +7 more
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Orchestral Actions of Angiopoietin-1 in Vascular Regeneration
Trends in Molecular Medicine, 2013Among many proangiogenic growth factors, angiopoietin-1 (Ang1, or ANGPT1) is unique because it can induce distinctive vascular remodeling through highly organized angiogenesis and tightening of endothelial cell (EC) junctions. These effects are mediated by synchronous activation of both vascular Tie2 and nonvascular integrin signaling, making Ang1 a ...
Koh Gou Young
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