Results 31 to 40 of about 27,286 (132)

The effects of two types of interval training on the association between cardiovascular fitness and atherogenic biomarkers with blood pressure in wWomen with overweight/obesity [PDF]

فیزیولوژی ورزش و فعالیت بدنی
Background and Purpose: Obesity, especially central body obesity, is related to cardiovascular diseases risk factors such as high blood pressure and hyperlipidemia.
Maryam Nazari, Vazgen Minasian, Silva Hovsepian   +2 more
doaj   +1 more source

A New Modality in Dyslipidemia Treatment: Antisense Oligonucleotide Therapy

Journal of Lipid and Atherosclerosis, 2022
There are unmet needs for pharmacologic agents beyond current medications, such as statins, to effectively lower low-density lipoprotein cholesterol levels to target goals, especially in patients with very high or extremely high risk.
Kyuho Kim, Sung Hee Choi
doaj   +1 more source

Metabolomic Signature of Angiopoietin-Like Protein 3 Deficiency in Fasting and Postprandial State [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2018
Objective— Loss-of-function (LOF) variants in the ANGPTL3 (angiopoietin-like protein 3) have been associated with low levels of plasma lipoproteins and decreased coronary artery disease risk.
Tikkanen, Emmi, Minicocci, Ilenia, Hällfors, Jenni, Di Costanzo, Alessia, D'Erasmo, Laura, Poggiogalle, Eleonora, Donini, Lorenzo Maria, Würtz, Peter, Jauhiainen, Matti, Olkkonen, Vesa M, Arca, Marcello   +10 more
openaire   +3 more sources

Causes, clinical findings and therapeutic options in chylomicronemia syndrome, a special form of hypertriglyceridemia

Lipids in Health and Disease, 2022
The prevalence of hypertriglyceridemia has been increasing worldwide. Attention is drawn to the fact that the frequency of a special hypertriglyceridemia entity, named chylomicronemia syndrome, is variable among its different forms.
György Paragh, Ákos Németh, Mariann Harangi, Maciej Banach, Péter Fülöp   +4 more
doaj   +1 more source

Gene knockdown of angiopoietin-like protein 3 reduces the occurrence and development of thoracic aortic aneurysms [PDF]

Jichu yixue yu linchuang, 2021
Objective To explore the role of angiopoietin-like protein 3 (ANGPTL3) in the development of thoracic aortic aneurysm (TAA) and its possible mechanism. Methods The TAA patients who underwent open surgical repair in Beijing Anzhen Hospital were selected
YU Hua-hui, JIAO Xiao-lu, YANG Yun-yun, LI Fan, SUN Qiu-ju, YU Yu, LYU Qian-wen, QIN Yan-wen
doaj  

A novel fusion protein consisting of anti-ANGPTL3 antibody and interleukin-22 ameliorates diabetic nephropathy in mice

Frontiers in Immunology, 2022
IntroductionThe pathogenic mechanisms of diabetic nephropathy (DN) include podocyte injury, inflammatory responses and metabolic disorders. Although the antagonism of Angiopoietin-like protein 3 (ANGPTL3) can alleviate proteinuria symptoms by inhibiting ...
Qianqian Ma, Xiaozhi Hu, Fangyu Liu, Zhonglian Cao, Lei Han, Kaicheng Zhou, Yu Bai, Yuting Zhang, Yanyang Nan, Qianying Lv, Jia Rao, Tao Wu, Xue Yang, Haidong He, Dianwen Ju, Dianwen Ju, Hong Xu   +16 more
doaj   +1 more source

Kaempferitrin improves meat quality of broiler chickens

Czech Journal of Animal Science, 2013
Angiopoietin-like protein 3 (Angptl3) may promote adipose formation. The objective of this study was to investigate the effect of kaempferitrin, a 3,7-diglycosyl flavone, on meat quality in broiler chickens and the mechanisms involved.
H.-B. Xiao, J. Fang, Z.-L. Sun
doaj   +1 more source

Triglyceride-Rich Lipoproteins: Their Role in Atherosclerosis

Revista de Investigación Clínica, 2022
The term “triglyceride-rich lipoproteins” (TRLs) includes chylomicrons and their remnants, very low-density lipoproteins (VLDL), and intermediate-density lipoproteins (IDL).
Yulino Castillo-Núñez, Enrique Morales-Villegas, Carlos A. Aguilar-Salinas   +2 more
doaj   +1 more source

Inhibiting angiopoietin-like protein 3: clear skies or clouds on the horizon? [PDF]

Eur Heart J
Hegele RA.
europepmc   +3 more sources

Simultaneously blocking ANGPTL3 and CD47 prevents the progression of atherosclerosis through regulating lipid metabolism, macrophagic efferocytosis and lipid peroxidation

Pharmacological Research
Atherosclerosis (AS) ultimately cause major adverse cardiovascular events (MACEs). While traditional strategies by lipid-reducing have reduced MACEs, many patients continue to face significant risks.
Xiaozhi Hu, Yanyang Nan, Yuting Zhang, Jiajun Fan, Hanqi Wang, Yu Bai, Yuanzhen Zhang, Xuyao Zhang, Zeguo Zhu, Zhonglian Cao, Xiaomiao Ye, Tao Wu, Shuwen Xu, Zhengyu Wu, Wei Hu, Dianwen Ju   +15 more
doaj   +1 more source