BackgroundElevated triglycerides or triglyceride-rich lipoproteins are an additional cause of cardiovascular (CV) disease. Given that patients with systemic lupus erythematosus (SLE) have a high prevalence of premature CV disease and show an altered ...
Juan Carlos Quevedo-Abeledo +10 more
doaj +1 more source
Pentraxin-3, Angiopoietin-Like Protein-3, Angiopoietin-Like Protein-4 and Angiopoietin-Like Protein-8 Levels in Morbid Obese Children [PDF]
A low-grade inflammatory state accompanies obesity and metabolic syndrome (MetS), which are risk factors for cardiovascular diseases (CVD) in children’s future lives. The aim of this study is to investigate possible associations of pentraxin 3 (PTX3), a promising new marker for CVDs, with angiopoietin-like proteins (ANGPTL) in morbid obese (MO ...
openaire +1 more source
Angiopoietin-like 4 (Angptl4) [PDF]
Angiopoietin-like 4 (Angptl4) is a secreted protein modulating triacylglycerol homeostasis. Its transcription is induced by glucocorticoids, which act to elevate circulating Angptl4 levels during fasting.
Koliwad, Suneil K +2 more
core +1 more source
Secretion of angiopoietin-like 4 protein from intestinal cells [PDF]
Background: Angiopoietin-like 4 (ANGPTL4) has been suggested to play a role in lipid metabolism as a regulatory protein of lipoprotein lipase activity. Intestinal secretion of ANGPTL4, which is regulated by fatty acids, may inhibit the activity of circulating lipoprotein lipase; but, recent studies suggest that it could also inhibit pancreatic lipase ...
Nielsen, Søren Drud +3 more
openaire +2 more sources
Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence [PDF]
Viral immune evasion strategies target key aspects of the host antiviral response. Recently, it has been recognized that Toll-like receptors (TLRs) have a role in innate defense against viruses.
Nathan W. Bartlett +24 more
core +1 more source
Increased Level of Angiopoietin Like Proteins 4 and 8 in People With Sleep Apnea [PDF]
Objective: Obstructive sleep apnea (OSA) is a sleep disorder caused by the complete or partial obstruction of the upper airways. The worldwide prevalence of OSA is increasing due to its close association with obesity epidemic and multiple health complications, such as hypertension, cardiovascular disease, and Type 2 diabetes. Angiopoietin-like protein (
Abdulmohsen Al-Terki +9 more
openaire +3 more sources
Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis [PDF]
We have investigated the function of mitotic kinesin-like protein (MKlp) 2, a kinesin localized to the central spindle, and demonstrate that its depletion results in a failure of cleavage furrow ingression and cytokinesis, and disrupts localization of ...
Mayer, Thomas U. +20 more
core +1 more source
Serum levels of angiopoietin-like protein 4 in polycystic ovary syndrome women with normal body mass index [PDF]
Introduction: Polycystic ovary syndrome (PCOS) is a complex endocrine disorder in women, and approximately 75% of women affected by PCOS are overweight. Angiopoietin-like protein 4 (ANGPTL4) is a potent inhibitor of lipoprotein lipase (LPL) enzyme.
Elham Rahmani +6 more
doaj +1 more source
Quantitation of serum angiopoietin-like proteins 3 and 4 in a Finnish population sample [PDF]
We have developed and validated quantitative ELISAs for human angiopoietin-like (ANGPTL)3 and 4 and correlated their serum levels with parameters of lipid and carbohydrate metabolism. For this study, we used a random subsample of the Health 2000 Health Examination Survey consisting of 125 men and 125 women, aged 30-94 years.
Robciuc, Marius R. +3 more
openaire +4 more sources
Up-regulated of Angiopoietin-Like Protein 4 Predicts Poor Prognosis in Cervical Cancer. [PDF]
Background: Angiopoietin-like protein 4 (ANGPTL4) has been demonstrated highly expressed in some cancers, but it also was downregulated in others through DNA methylation. However, the expression status of ANGPTL4 in cancer of cervix remains unclear. Thus, our present study attempts to investigate the role of ANGPTL4 in the prognosis of patients with ...
Nie D, Zheng Q, Liu L, Mao X, Li Z.
europepmc +4 more sources

