Results 31 to 40 of about 19,473,374 (191)

Serum levels of angiopoietin-like protein 4 in polycystic ovary syndrome women with normal body mass index [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2018
Introduction: Polycystic ovary syndrome (PCOS) is a complex endocrine disorder in women, and approximately 75% of women affected by PCOS are overweight. Angiopoietin-like protein 4 (ANGPTL4) is a potent inhibitor of lipoprotein lipase (LPL) enzyme.
Elham Rahmani, Samad Akbarzadeh, Abdollah Nazari, Niloofar Motamed, Soraya Ghodrati, Anahita Abasi Fard, Marzieh Zohrabi   +6 more
doaj   +1 more source

Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence [PDF]

, 2005
Viral immune evasion strategies target key aspects of the host antiviral response. Recently, it has been recognized that Toll-like receptors (TLRs) have a role in innate defense against viruses.
Nathan W. Bartlett, Geoffrey L. Smith, Haga, Ismar R, Geraldine Maloney, Bowie, Andrew G., Bartlett, Nathan W., Martina Schröder, Ismar R. Haga, Haga, Ismar R., Patrick C. Reading, Andrew G. Bowie, Fitzgerald, Katherine A, Smith, Geoffrey L, Schroeder, Martina, Reading, Patrick C, Smith, Geoffrey L., Katherine A. Fitzgerald, Bartlett, Nathan W, Julianne Stack, Maloney, Geraldine, Bowie, Andrew G, Schröder, Martina, Reading, Patrick C., Stack, Julianne, Fitzgerald, Katherine A.   +24 more
core   +1 more source

Targeting metabolic flexibility via angiopoietin-like 4 protein sensitizes metastatic cancer cells to chemotherapy drugs

Molecular Cancer, 2018
Overcoming multidrug resistance has always been a major challenge in cancer treatment. Recent evidence suggested epithelial-mesenchymal transition plays a role in MDR, but the mechanism behind this link remains unclear.
Maegan Miang Kee Lim, Jonathan Wei Kiat Wee, Jen Chi Soong, Damien Chua, Wei Ren Tan, Marco Lizwan, Yinliang Li, Ziqiang Teo, Wilson Wen Bin Goh, Pengcheng Zhu, Nguan Soon Tan   +10 more
doaj   +1 more source

A randomised, controlled, crossover study of the effect of diet on angiopoietin-like protein 4 (ANGPTL4) through modification of the gut microbiome

Journal of Nutritional Science, 2016
Angiopoietin-like protein 4 (ANGPTL4) is a lipoprotein lipase inhibitor that is involved in lipid metabolism and angiogenesis. Animal studies have suggested that the ANGPTL4 protein is modulated by the gut microbiota, possibly through increased ...
Trine Blædel, Jacob B. Holm, Ulrik K. Sundekilde, Mette S. Schmedes, Anne L. Hess, Janne K. Lorenzen, Karsten Kristiansen, Trine K. Dalsgaard, Arne Astrup, Lesli H. Larsen   +9 more
doaj   +1 more source

Decreased fat storage by Lactobacillus paracasei is associated with increased levels of angiopoietin-like 4 protein (ANGPTL4). [PDF]

PLoS ONE, 2010
BACKGROUND: Intervention strategies for obesity are global issues that require immediate attention. One approach is to exploit the growing consensus that beneficial gut microbiota could be of use in intervention regimes.
Linda Aronsson, Ying Huang, Paolo Parini, Marion Korach-André, Janet Håkansson, Jan-Åke Gustafsson, Sven Pettersson, Velmurugesan Arulampalam, Joseph Rafter   +8 more
doaj   +1 more source

Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis.

, 2011
OBJECTIVE: To determine the utility of angiopoietin-1 and angiopoietin-2 as potentially novel biomarkers of morbidity and mortality in patients with severe sepsis. DESIGN: Multicenter longitudinal cohort study.
Hawkes, Michael, Michael Hawkes, Nimerta Rajwans, W. Conrad Liles, Fox-Robichaud, Alison, Lisa J. Toltl, Alison Fox-Robichaud, Patricia C. Liaw, Cook, Deborah J, Ricciuto, Daniel R, Lafferty, Erin I, Rajwans, Nimerta, Kain, Kevin C, Andrea L. Conroy, Kevin C. Kain, Conroy, Andrea L, Daniel R. Ricciuto, Deborah J. Cook, Kahnamoui, Kamyar, Erin I. Lafferty, dos Santos, Claudia C, Liaw, Patricia C, Liles, W Conrad, Kamyar Kahnamoui, Toltl, Lisa J, Claudia C. dos Santos   +25 more
core   +1 more source

Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis [PDF]

, 2003
We have investigated the function of mitotic kinesin-like protein (MKlp) 2, a kinesin localized to the central spindle, and demonstrate that its depletion results in a failure of cleavage furrow ingression and cytokinesis, and disrupts localization of ...
Mayer, Thomas U., Erich A. Nigg, Francis A. Barr, Neef, Rüdiger, Josephine Sutcliffe, Kopajtich, R., Rüdiger Neef, Nigg, E. A., Robert Kopajtich, Mayer, T. U., Thomas U. Mayer, Christian Preisinger, Preisinger, C., Neef, R., Sutcliffe, J., Barr, F. A., Nigg, Erich A., Sutcliffe, Josephine, Kopajtich, Robert, Preisinger, Christian, Barr, Francis A.   +20 more
core   +1 more source

ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression

Nature Communications, 2016
Angiopoietin-like 4 protein (ANGPTL4) is a regulator of lipoprotein metabolism whose role in atherosclerosis has been controversial. Here the authors show that ANGPTL4 deficiency in haematopoietic cells increases atherogenesis by promoting myeloid ...
Binod Aryal, Noemi Rotllan, Elisa Araldi, Cristina M. Ramírez, Shun He, Benjamin G. Chousterman, Ashley M. Fenn, Amarylis Wanschel, Julio Madrigal-Matute, Nikhil Warrier, Jose L. Martín-Ventura, Filip K. Swirski, Yajaira Suárez, Carlos Fernández-Hernando   +13 more
doaj   +1 more source

Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children. [PDF]

, 2009
BACKGROUND: Limited tools exist to identify which individuals infected with Plasmodium falciparum are at risk of developing serious complications such as cerebral malaria (CM). The objective of this study was to assess serum biomarkers that differentiate
Hawkes, Michael, Nimerta Rajwans, Michael Hawkes, Kevin C Kain, Lafferty, Erin I., John, Chandy C, Sornchai Looareesuwan, Srivicha Krudsood, Tangpukdee, Noppadon, Lafferty, Erin I, Looareesuwan Sornchai, Fiona E Lovegrove, Krudsood, Srivicha, John Chandy C., Rajwans, Nimerta, Opoka, Robert, Noppadon Tangpukdee, Hawkes Michael, Lafferty Erin I., Lovegrove Fiona E., Kain, Kevin C, Looareesuwan, Sornchai, Lovegrove, Fiona E., Opoka Robert O., Krudsood Srivicha, Kain, Kevin C., Erin I Lafferty, Kain Kevin C., Robert O Opoka, Lovegrove, Fiona E, Rajwans Nimerta, John, Chandy C., W Conrad Liles, Liles, W. Conrad, Tangpukdee Noppadon, Liles, W Conrad, Chandy C John, Opoka, Robert O, Liles W. Conrad   +38 more
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ANGPTL4 Expression in Ovarian Granulosa Cells Is Associated With Polycystic Ovary Syndrome

Frontiers in Endocrinology, 2022
ObjectivesThis study aims to characterize the expression of ANGPTL4 in ovarian granulosa cells (GCs) and its association with polycystic ovary syndrome (PCOS).MethodsThis study included 104 PCOS patients and 112 women in control group undergoing in vitro
Qi Jiang, Qi Jiang, Qi Jiang, Qi Jiang, Qi Jiang, Ye Pan, Ye Pan, Ye Pan, Ye Pan, Ye Pan, Ping Li, Yanjun Zheng, Yanjun Zheng, Yanjun Zheng, Yanjun Zheng, Yanjun Zheng, Yuehong Bian, Yuehong Bian, Yuehong Bian, Yuehong Bian, Yuehong Bian, Wenqi Wang, Wenqi Wang, Wenqi Wang, Wenqi Wang, Wenqi Wang, Guihua Wu, Tian Song, Tian Song, Tian Song, Tian Song, Tian Song, Yuhua Shi, Yuhua Shi   +33 more
doaj   +1 more source