Results 41 to 50 of about 19,473,374 (191)

Expression of angiopoietin-like 4 in human gastric cancer: ANGPTL4 promotes venous invasion [PDF]

, 2010
There is strong evidence that the angiopoietin family is involved in the regulation of tumour progression, cellular growth and differentiation. Recently, it has been reported that angiopoietin-like 4 (ANGPTL4) in cancer cell promotes the metastatic ...
Taguchi, Takashi, Hirakawa, Hiroshi, Nagayasu, Takeshi, Abe, Kuniko, Nakayama, Toshiyuki, Shibata, Kenichiro   +5 more
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Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

Elevated Plasma Angiopoietin-like 4 Protein Levels in Adult Patients with Dengue

Viruses
Dengue virus infection can cause severe complications due to vascular leakage. Angiopoietin-like protein 4 (ANGPTL4) regulates vascular permeability, but its role in dengue pathogenesis is unclear.
Win Khaing, Suk Hiang Lau, Tun-Linn Thein, Nguan Soon Tan, Sylvie Alonso, Shawn Vasoo, Po Ying Chia, David Chien Boon Lye, Yee Sin Leo, Vincent T. K. Chow   +9 more
doaj   +1 more source

Angiopoietin-like protein 3 markedly enhanced in the hyperlipidemia related proteinuria

Lipids in Health and Disease, 2019
Background Angiopoietin-like protein 3(ANGPTL3) is well acknowledged as a key regulator of lipid metabolism. Now, there have not been enough data to explain the mechanism of hyperlipidemia related proteinuria.
Xia Gao, Yanhong Suo, Min Zhang, Yan Wang, Xin Gao, Qiu Bing, Qingju Liu   +6 more
doaj   +1 more source

Angiopoietin‐like 4 production upon treatment with hypoxia and L‐mimosine in periodontal fibroblasts

, 2019
Background and objective A key factor in the modulation of angiogenesis as well as in bone resorption is angiopoietin-like 4. However, the role of angiopoietin-like 4 in periodontal tissue is unknown.
Agis, Hermann, Moritz, Andreas, Andreas Moritz, Schellner, Alwina, Janjić, Klara, Engenhart, Alexander, Kernstock, Kurt, Alexander Engenhart, Schädl, Barbara, Alwina Schellner, Hermann Agis, Barbara Schädl, Klara Janjić, Kurt Kernstock   +13 more
core   +1 more source

The role of Angiopoietin-like protein 4 in macrophage activation

, 2020
Angiopoietin-like protein 4 (Angptl4) is a matricellular protein that associates with extracellular matrix proteins, mediating complex cell-cell, and cell-matrix interactions.
Wee, Jonathan Wei Kiat
core   +1 more source

Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) but not PPARalpha serves as a plasma free fatty acid sensor in liver [PDF]

, 2009
Peroxisome proliferator-activated receptor alpha (PPARalpha) is an important transcription factor in liver that can be activated physiologically by fasting or pharmacologically by using high-affinity synthetic agonists.
Degenhardt, Tatjana, Degerhardt, T., Kersten, A.H., Müller, Michael, Koppen, A., Sanderson, L., Kalkhoven, E., Müller, M.R., Koppen, Arjen, Sanderson, Linda M, Desvergne, Beatrice, Desvergne, B., Kalkhoven, Eric, Kersten, Sander, Sanderson, L.M., Degenhardt, T., Kersten, S., Müller, M.   +17 more
core   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Feeding Angptl4−/− mice trans fat promotes foam cell formation in mesenteric lymph nodes without leading to ascites[S]

Journal of Lipid Research, 2017
Angiopoietin-like 4 (ANGPTL4) regulates plasma triglyceride levels by inhibiting LPL. Inactivation of ANGPTL4 decreases plasma triglycerides and reduces the risk of coronary artery disease.
Antwi-Boasiako Oteng, Asmita Bhattacharya, Susanne Brodesser, Ling Qi, Nguan Soon Tan, Sander Kersten   +5 more
doaj   +1 more source

Functional characterization of Angptl4 protein [PDF]

, 2009
Background: Elevated plasma triglycerides (TG) are increasingly recognized as a risk factor for atherosclerosis. A new adipocytokine was discovered by several groups which is referred to as Angptl4 (Angiopoietin-like protein 4).
Lichtenstein, L.L.
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