Results 41 to 50 of about 75,908 (219)

Role of Angiopoietin-like protein 4 (ANGPTL4) as a Predictive marker for Diabetic Nephropathy in type 2 Diabetes [PDF]

Al-Azhar International Medical Journal, 2022
Background: Angiopoietin-like protein 4 (ANGPTL4) is a glycoprotein that regulates LPL activity during fasting and thereby affects triglyceride metabolism.
Amr Rezk, hossam aladl, youssef Ahmed, ahmed abd elhakam   +3 more
doaj   +1 more source

The role of angiopoietin-like protein 4 in phenylephrine-induced cardiomyocyte hypertrophy. [PDF]

Biosci Rep, 2019
Abstract Angiopoietin-like protein 4 (ANGPTL4) is a multifunctional secreted protein that can be induced by fasting, hypoxia and glucocorticoids. ANGPTL4 has been associated with a variety of diseases; however, the role of ANGPTL4 in cardiac hypertrophy remains poorly understood. In our study, we aimed to explore the effect of ANGPTL4 on
Sun Y, Li Y, Liu C, Xue R, Dong B, Huang H, Peng L, Liu J, Dong Y.   +8 more
europepmc   +4 more sources

The Prognostic Value of ANGPTL-4 in Acute Coronary Syndrome: A Prospective Cohort Study [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Coronary Artery Disease (CAD) is one of the leading causes of mortality and morbidity worldwide and Acute Coronary Syndrome (ACS) is one of the predominant causes of Cardiovascular Deaths (CVD).
Luxitaa Goenka, Ritwika Sinha Ray, Vengatesh Munnusamy, VE Dhandapani, Melvin George   +4 more
doaj   +1 more source

Fasting-induced adipose factor/angiopoietin-like protein 4 as an adipokine

, 2011
The adipose tissue serves as a major endocrine organ by secreting a large number of metabolically and/or immunologically active factors. One of the proteins secreted by adipose and other tissues is fasting-induced adipose factor (FIAF)/ angiopoietin-like protein 4 (Angptl4), a member of the family of angiopoietins and angiopoietin-like protein. Angptl4
Kersten, Sander
openaire   +2 more sources

Regulation of angiopoietin-like protein 4 production during and after exercise. [PDF]

Physiol Rep, 2014
Angiopoietin-like protein 4 (ANGPTL4) may regulate lipoprotein lipase-dependent plasma clearance of triacylglycerol from skeletal muscle during exercise. The aim of this study was to examine the importance of muscle in regulating ANGPTL4 in response to exercise.
Norheim F, Hjorth M, Langleite TM, Lee S, Holen T, Bindesbøll C, Stadheim HK, Gulseth HL, Birkeland KI, Kielland A, Jensen J, Dalen KT, Drevon CA.   +12 more
europepmc   +5 more sources

Oligomerization and Regulated Proteolytic Processing of Angiopoietin-like Protein 4 [PDF]

Journal of Biological Chemistry, 2004
Angiopoietin-like protein 4 (Angptl4) is a recently identified circulating protein expressed primarily in adipose tissue and liver. Also known as peroxisome proliferator-activated receptor (PPAR)-gamma angiopoietin-related, fasting induced adipose factor, and hepatic fibrinogen/angiopoietin-related protein, recombinant Angptl4 causes increase of plasma
Hongfei, Ge, Guoqing, Yang, Lu, Huang, Daniel L, Motola, Tiffany, Pourbahrami, Cai, Li   +5 more
openaire   +2 more sources

The effect of three acid-resistant isolated proteins from Lactobacillus casei on lipid and carbohydrate metabolism pathway-related genes: An In vitro study

Biomedical and Biotechnology Research Journal, 2021
Background: The role of Lactobacillus casei on human health is well documented. However, little is known about their protein effects on food digestion. Therefore, in the present study, we aimed to investigate the efficacy of three proteins of L. casei on
Golgis Karimi, Mina Saadat, Shivasadat Gheflat, Bahram Kazemi, Mojgan Bandehpour   +4 more
doaj   +1 more source

Angiopoietin-like 4 Interacts with Matrix Proteins to Modulate Wound Healing* [PDF]

Journal of Biological Chemistry, 2010
A dynamic cell-matrix interaction is crucial for a rapid cellular response to changes in the environment. Appropriate cell behavior in response to the changing wound environment is required for efficient wound closure. However, the way in which wound keratinocytes modify the wound environment to coordinate with such cellular responses remains less ...
Goh, Y.Y., Pal, M., Chong, H.C., Zhu, P., Tan, M.J., Punugu, L., Tan, C.K., Huang, R.L., Sze, S.K., Yang Tang, M.B., Ling Ding, J., Kersten, A.H., Tan, N.S.   +12 more
openaire   +2 more sources

Comparison of angiopoietin-like protein 3 and 4 reveals structural and mechanistic similarities [PDF]

Journal of Biological Chemistry, 2021
Elevated plasma triglycerides are a risk factor for coronary artery disease, which is the leading cause of death worldwide. Lipoprotein lipase (LPL) reduces triglycerides in the blood by hydrolyzing them from triglyceride-rich lipoproteins to release free fatty acids.
Kathryn H. Gunn, Aspen R. Gutgsell, Yongmei Xu, Caitlin V. Johnson, Jian Liu, Saskia B. Neher   +5 more
openaire   +2 more sources

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source