Results 11 to 20 of about 4,326 (177)

Angiopoietin-Like Protein 4 and Insulin-Like Growth Factor-1 Expression in Invasive Breast Carcinoma in Young Women

Pathophysiology, 2022
Biomarker identification is imperative for invasive breast carcinoma, which is more aggressive and associated with higher mortality and worse prognosis in younger patients (50 years).
Zaleha Kamaludin, Alaa Siddig, Najib Majdi Yaacob, Alfred K. Lam, Wan Faiziah Wan Abdul Rahman   +4 more
doaj   +2 more sources

Angiopoietin-like 4 (ANGPTL4) Suppression Ameliorates Lupus Nephritis in MRL/lpr Mice by Inactivating NLRP3 Inflammasome and Inhibiting Inflammatory Response [PDF]

Iranian Journal of Immunology, 2023
Background: Lupus nephritis (LN) refers to the injury caused by systemic lupus erythematosus (SLE) involving the kidneys. A previous study identified angiopoietin-like protein 4 (ANGPTL4) as a novel urinary biomarker for tracking disease activity in LN ...
Dan Luo, Jun Li, Manli Hu, You Wang, Pei Pi, Min Ning, Jun Wu   +6 more
doaj   +2 more sources

Identification and characterization of angiopoietin-like 4 (ANGPTL4) interacting proteins in wound repair [PDF]

, 2019
Cutaneous wound healing is a complex and highly coordinated process of proliferation and migration of keratinocytes at the wound edge through interactions of different signaling molecules. Growth factors, transmembrane protein integrins and extracellular matrix play an important role in epidermal wound healing process, although the interplay among ...
Mintu Pal
openaire   +4 more sources

Decoding the role of angiopoietin-like protein 4/8 complex–mediated plasmin generation in the regulation of LPL activity

Journal of Lipid Research, 2023
After feeding, adipose tissue lipoprotein lipase (LPL) activity should be maximized, therefore the potent LPL-inhibitory activity of angiopoietin-like protein 4 (ANGPTL4) must be blocked by ANGPTL8 through formation of ANGPTL4/8 complexes.
Yan Q. Chen, Eugene Y. Zhen, Anna M. Russell, Mariam Ehsani, Robert W. Siegel, Yuewei Qian, Robert J. Konrad   +6 more
doaj   +2 more sources

Angiopoietin-like 4 regulates epidermal differentiation.

PLoS ONE, 2011
The nuclear hormone receptor PPARβ/δ is integral to efficient wound re-epithelialization and implicated in epidermal maturation. However, the mechanism underlying the latter process of epidermal differentiation remains unclear.
Mintu Pal, Ming Jie Tan, Royston-Luke Huang, Yan Yih Goh, Xiao Ling Wang, Mark Boon Yang Tang, Nguan Soon Tan   +6 more
doaj   +2 more sources

mRNA Expression of Ovine Angiopoietin-like Protein 4 Gene in Adipose Tissues [PDF]

Asian-Australasian Journal of Animal Sciences, 2016
Angiopoietin-like protein 4 (ANGPTL4) is involved in a variety of functions, including lipoprotein metabolism and angiogenesis. To reveal the role of ANGPTL4 in fat metabolism of sheep, ovine ANGPTL4 mRNA expression was analyzed in seven adipose tissues ...
Jing Zhang, Jiong-Jie Jing, Xia-Li Jia, Li-Ying Qiao, Jian-Hua Liu, Chen Liang, Wen-Zhong Liu   +6 more
doaj   +2 more sources

Decreased Fat Storage by Lactobacillus Paracasei Is Associated with Increased Levels of Angiopoietin-Like 4 Protein (ANGPTL4)

PLoS ONE, 2010
Intervention strategies for obesity are global issues that require immediate attention. One approach is to exploit the growing consensus that beneficial gut microbiota could be of use in intervention regimes. Our objective was to determine the mechanism by which the probiotic bacteria Lactobacillus paracasei ssp paracasei F19 (F19) could alter fat ...
Aronsson, Linda, Huang, Ying, Parini, Paolo, Korach-André, Marion, Håkansson, Janet, Gustafsson, Jan-Åke, Pettersson, Sven, Arulampalam, Velmurugesan, Rafter, Joseph   +8 more
openaire   +5 more sources

Angiopoietin-like protein 4 is an exercise-induced hepatokine in humans, regulated by glucagon and cAMP [PDF]

Molecular Metabolism, 2017
Objective: Angiopoietin-like protein-4 (ANGPTL4) is a circulating protein that is highly expressed in liver and implicated in regulation of plasma triglyceride levels.
Bodil Ingerslev, Jakob S. Hansen, Christoph Hoffmann, Jens O. Clemmesen, Niels H. Secher, Mika Scheler, Martin Hrabĕ de Angelis, Hans U. Häring, Bente K. Pedersen, Cora Weigert, Peter Plomgaard   +10 more
doaj   +3 more sources

Fatty Acids and Hypoxia Stimulate the Expression and Secretion of the Adipokine ANGPTL4 (Angiopoietin-Like Protein 4/ Fasting-Induced Adipose Factor) by Human Adipocytes

Lifestyle Genomics, 2011
<i>Background/Aims:</i> Hypoxia occurs in white adipose tissue in obesity, modulating the expression and release of specific inflammation-related adipokines. ANGPTL4 (angiopoietin-like protein 4/fasting-induced adipose factor), which is implicated in angiogenesis, lipid metabolism and glucose homeostasis, is a major hypoxia-sensitive gene ...
Pedro, González-Muniesa, Cristiane, de Oliveira, Fátima, Pérez de Heredia, Mary P, Thompson, Paul, Trayhurn   +4 more
openaire   +3 more sources

Angiopoietin-like protein 4 dysregulation in kidney diseases: a promising biomarker and therapeutic target [PDF]

Frontiers in Pharmacology
The global burden of renal diseases is increasingly severe, underscoring the need for in-depth exploration of the molecular mechanisms underlying renal disease progression and the development of potential novel biomarkers or therapeutic targets ...
Yan Li, Yan Li, Yan Li, Yuxin Zhang, Yuxin Zhang, Yuxin Zhang, Mengxia Cao, Mengxia Cao, Mengxia Cao, Tingting Yuan, Tingting Yuan, Tingting Yuan, Santao Ou, Santao Ou, Santao Ou   +14 more
doaj   +2 more sources