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[Correlation of Serum Neuron-Specific Enolase, Angiopoietin-1, and Angiopoietin-Like Protein-3 With Disease Severity and Their Prognostic Value in Patients With Cerebral Infarction]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Liu J, Gao H, Liu Y.
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Overexpression of angiopoietin-1 and angiopoietin-2 in hepatocellular carcinoma

Journal of Hepatology, 2004
Hepatocellular carcinoma (HCC) is a highly vascular tumor. Angiopoietin-1 and Angiopoietin-2 have been shown to be involved in tumor angiogenesis. We investigated the expression of Angiopoietin-1 and Angiopoietin-2 in HCC.The expression of Angiopoietin-1 and Angiopoietin-2 mRNAs in cultured hepatoma cells under hypoxic conditions and in HCC and ...
Takuji, Torimura, Takato, Ueno, Motoaki, Kin, Riko, Harada, Eitaro, Taniguchi, Toru, Nakamura, Ryuichiro, Sakata, Osamu, Hashimoto, Masaharu, Sakamoto, Ryukichi, Kumashiro, Michio, Sata, Osamu, Nakashima, Hirohisa, Yano, Masamichi, Kojiro   +13 more
openaire   +2 more sources

Angiopoietin-1 and Angiopoietin-2 Inhibitors: Clinical Development

Current Oncology Reports, 2019
The purpose of this review is to discuss the current understanding of the Tie2-angiopoietin system and its role in tumor growth and metastasis. This review also focuses on preclinical and clinical data published to date that have evaluated Tie2-angiopoietin inhibition.Tie2 inhibition has shown significant promise in preclinical models, notable for ...
Jessica, Gillen, Debra, Richardson, Kathleen, Moore   +2 more
openaire   +2 more sources

Dynamic changes in serum angiopoietin-1, angiopoietin-2, and angiopoietin-2/angiopoietin-1 ratio in acute myocardial infarction patients treated with primary percutaneous coronary intervention

Biomarkers, 2012
Angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2) play divergent roles in myocardial ischemia and reperfusion injury.To investigate serum Ang-1 and Ang-2 levels in ST-segment elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (PCI).Serum Ang-1 and Ang-2 were measured in 85 STEMI patients in the ...
Ming Cui, Lijun Guo, Lin Mi
exaly   +3 more sources

Angiopoietin-1 and Myeloma-Induced Angiogenesis

Leukemia & Lymphoma, 2005
Multiple myeloma (MM) is a plasma cell malignancy characterized by an increase of the bone marrow angiogenesis. Angiopoietin-1 (Ang-1) is a critical factor in the regulation of physiological and pathological vessel formation that acts by binding to a specific receptor Tie2 expressed on endothelial cells.
GIULIANI, Nicola, COLLA S, MORANDI F, RIZZOLI, Vittorio   +3 more
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Angiopoietin 1 and angiopoietin 2 in follicular fluid of women undergoing a long protocol

Fertility and Sterility, 2011
To determine the concentrations of angiopoietin 1 (ANGPT1) and ANGPT2 in individual human preovulatory follicles in relation to their diameter or volume to clarify the role of these molecules in folliculogenesis.Prospective study.Research laboratory at Kansai Medical University, Osaka, Japan.Twenty-three women undergoing IVF.On the day of oocyte ...
Akemi Nishigaki, Hidetaka Okada, Katsuhiko Yasuda   +2 more
exaly   +3 more sources

Vitreous Levels of Angiopoietin-1 and Angiopoietin-2 in Eyes With Retinopathy of Prematurity

American Journal of Ophthalmology, 2011
To determine the vitreous levels of angiopoietin (Ang)-1 and Ang-2 in eyes with retinopathy of prematurity (ROP), and to determine the correlation between the 2 levels.Retrospective case-control study.Forty-eight eyes with stage 4 ROP were studied. Six eyes with congenital cataract were used as controls.
Tatsuhiko, Sato, Chiharu, Shima, Shunji, Kusaka   +2 more
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Differential expression of angiopoietin-1 and angiopoietin-2 in colon carcinoma [PDF]

Cancer, 2001
Angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2) are important regulators of endothelial cell (EC) survival. Current models suggest that an increase in Ang-2 expression in ECs leads to the initiation of angiogenesis. The authors hypothesized that the imbalance of Ang-1 and Ang-2 activities in colon carcinoma leads to a net gain in Ang-2 function ...
L M Ellis, Wenbiao Liu, Corazon D Bucana
exaly   +3 more sources

ANGIOPOIETIN-1 IN THE TREATMENT OF ISCHEMIA AND SEPSIS

Shock, 2009
Angiogenic factors have been the focus of a great deal of research for the treatment of ischemic diseases. Described just more than 10 years ago, angiopoietin 1 (Ang-1) has shown promising results in I/R models. Angiopoietin 1 is essential for both embryonic vasculogenesis and adult angiogenesis.
Nathan M, Novotny, Tim, Lahm, Troy A, Markel, Paul R, Crisostomo, Meijing, Wang, Yue, Wang, Jiangning, Tan, Daniel R, Meldrum   +7 more
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Roles of Angiopoietin-1 and Angiopoietin-2 on Airway Microvascular Permeability in Asthmatic Patients

Chest, 2007
Vascular endothelial growth factor (VEGF) increases microvascular permeability. Recently, considerable attention has been devoted to the physiologic roles of angiopoietin-1 and angiopoietin-2 as regulatory factors of VEGF. This study was designed to examine the roles of angiopoietin-1 and angiopoietin-2 in controlling airway microvascular permeability ...
Hiroshi, Kanazawa, Saeko, Nomura, Kazuhisa, Asai   +2 more
openaire   +2 more sources