Serum angiopoietin-2/angiopoietin-1 ratio is associated with cardiovascular and all-cause mortality in peritoneal dialysis patients: a prospective cohort study [PDF]
Renal FailureIntroduction Our objective was to examine the factors associated with the serum angiopoietin-2/angiopoietin-1 (Angpt-2/Angpt-1) ratio in peritoneal dialysis (PD) patients and to investigate the association between Angpt-2/Angpt-1 ratio and cardiovascular
Han Li +11 more
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Angiopoietin‐1, Angiopoietin‐2 and Vascular Endothelial Growth Factor Levels in Canine Leishmaniosis [PDF]
Veterinary Medicine and ScienceBackground Canine leishmaniosis (CanL) is a zoonotic vector–borne disease and is primarily associated with systemic inflammation, endothelial dysfunction and immune dysregulation. Although angiopoietins (Ang) and vascular endothelial growth factor (VEGF)
Gamze Gultekin +10 more
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Urinary Exosomal Tissue TIMP and Angiopoietin-1 Are Preoperative Novel Biomarkers of Well-Differentiated Thyroid Cancer [PDF]
Biomedicines, 2022 Finding non-invasive and sensitive biomarkers for early screening of high-risk patients remains important in clinical practice. A higher concentration of urine exosomal thyroglobulin protein was found in late-stage patients with thyroid carcinoma ...
Chih-Yuan Wang +3 more
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MicroRNA Profiles Targeting Angiopoietin-1, Angiopoietin-2, and TEK Receptor Tyrosine Kinase-2 Genes Associated with Angiogenesis in Proliferative Diabetic Retinopathy [PDF]
Türk Oftalmoloji DergisiObjectives: This study aims to assess the concentrations of angiopoietin-1, angiopoietin-2, and Tie-2, which are implicated in the pathophysiology of proliferative diabetic retinopathy (PDR), in the vitreous fluid and to evaluate the expression profiles ...
Hilal Sancar +3 more
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Angiopoietin-1 promotes triple-negative breast cancer cell proliferation by upregulating carboxypeptidase A4 [PDF]
Acta Biochimica et Biophysica Sinica, 2023 Angiopoietin-1 (ANG1) is a pro-angiogenic regulator that contributes to the progression of solid tumors by stimulating the proliferation, migration and tube formation of vascular endothelial cells, as well as the ...
Liu Xue +7 more
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Treatment With an Angiopoietin-1 Mimetic Peptide Improves Cognitive Outcome in Rats With Vascular Dementia [PDF]
Frontiers in Cellular Neuroscience, 2022 Background and PurposeVascular dementia (VaD) is a complex neurodegenerative disease affecting cognition and memory. There is a lack of approved pharmacological treatments specifically for VaD.
Lauren Culmone +10 more
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Serum Angiopoietin-1 and Angiopoietin-2 as Biomarkers of Pulmonary Hemodynamic Burden in COPD-Associated Pulmonary Hypertension: A Cross-Sectional Study [PDF]
Advances in Respiratory MedicinePurpose: Pulmonary hypertension (PH) is a serious complication of COPD associated with worse outcomes. Reliable circulating biomarkers of pulmonary vascular involvement are lacking. Angiopoietin-1 (ANGP-1) and angiopoietin-2 (ANGP-2) regulate endothelial
Jyoti Bajpai +7 more
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Effect of HIV‐1 Infection on Angiopoietin 1 and 2 Levels and Measures of Microvascular and Macrovascular Endothelial Dysfunction [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background Individuals infected with HIV have an increased risk of developing cardiovascular disease; yet, the underlying mechanisms remain unknown. Recent evidence has implicated the Tie‐2 tyrosine kinase receptor system and its associated ligands ANG1 (
Anjali B. Thakkar +10 more
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Probiotics in Combination with C16 Peptide and Angiopoietin-1 Synergistically Ameliorate Multiple Sclerosis in Mice [PDF]
Drug Design, Development and TherapyQiang Li,1 Yi Zhao,1 Lu Bai,2 Lu-Ping Tang,1 Shu Han21The Emergency Department, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310009, People’s Republic of China; 2Institute of Anatomy, Medical College ...
Li Q, Zhao Y, Bai L, Tang LP, Han S
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Angiopoietin-1 induces survival and proliferation of hair follicle dermal papilla cells through integrin α5β1 signaling [PDF]
Frontiers in MedicineBackgroundAndrogenetic alopecia is a common form of hair loss primarily mediated by dihydrotestosterone (DHT), which induces apoptosis and inhibits proliferation in dermal papilla cells (DPCs). Current treatments, such as minoxidil and finasteride, often
Jang-Hyuk Yun
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