Results 21 to 30 of about 107,707,414 (242)
Refractory kaposiform lymphangiomatosis relieved by splenectomy
Frontiers in Pediatrics, 2023 IntroductionKaposiform lymphangiomatosis (KLA) is a rare and complex lymphatic anomaly with a poor prognosis. There is no standard treatment, and drug therapies are the most common therapeutic method.
Yuru Lan +4 more
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EBioMedicine, 2021 Background: Malaria during pregnancy is a major contributor to the global burden of adverse birth outcomes including fetal growth restriction, preterm birth, and fetal loss.
Vanessa Tran +15 more
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Effects of laser photocoagulation on serum angiopoietin-1, angiopoietin-2, angiopoietin-1/angiopoietin-2 ratio, and soluble angiopoietin receptor Tie-2 levels in type 2 diabetic patients with proliferative diabetic retinopathy [PDF]
International Journal of Ophthalmology, 2014 AIM: To determine the effects of laser photocoagulation on serum levels of angiopoietin-1 (Ang-1), angiopoietin-2 (Ang-2), soluble angiopoietin receptor Tie-2 (Tie-2), Ang-1/Ang-2 ratio and vascular endothelial growth factor (VEGF) in patients with type ...
Qiao-Ying You +3 more
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Suppression of Diabetic Retinopathy with Angiopoietin-1 [PDF]
The American Journal of Pathology, 2002 Diabetic retinopathy remains a leading cause of irreversible blindness. A critical early pathology in the disease is the adhesion of leukocytes to the retinal vasculature, a process that occurs, in part, via intercellular adhesion molecule-1. Once leukocyte adhesion occurs, endothelial cell injury ensues, as does blood-retinal barrier breakdown.
Antonia M, Joussen +12 more
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Hepatology, EarlyView., 2022 Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince +30 more
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Chinese Journal of Physiology, 2022 Buyang Huanwu decoction (BYHWD), a classical prescription for ischemic stroke, has been reported to promote angiogenesis after focal ischemia. However, the mechanisms of the contribution of BYHWD on angiogenesis are still unclear.
Ying Zhou +6 more
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Early vessel destabilization mediated by Angiopoietin-2 and subsequent vessel maturation via Angiopoietin-1 induce functional neovasculature after ischemia. [PDF]
, 2013 We assessed whether Angiopoietin-2 (Ang2), a Tie2 ligand and partial antagonist of Angiopoietin-1 (Ang1), is required for early vessel destabilization during postischemic angiogenesis, when combined with vascular growth factors.
Di Qin (107446) +27 more
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BMC Research Notes, 2020 Objective High prevalence of chronic ulcers and the burden of disease necessitate the increasingly significant production of new recombinant proteins in the world.
Hamzeh Alipour +3 more
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Whole blood angiopoietin-1 and -2 levels discriminate cerebral and severe (non-cerebral) malaria from uncomplicated malaria [PDF]
, 2009 Background Severe and cerebral malaria are associated with endothelial activation. Angiopoietin-1 (ANG-1) and angiopoietin-2 (ANG-2) are major regulators of endothelial activation and integrity.
Liles W Conrad +21 more
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Vascular stabilization by angiopoietin-1
Folia Pharmacologica Japonica, 2010 アンジオポエチン–1（Ang1）は，血管内皮細胞に発現するTie2受容体を介して，血管構造の安定化と血管新生の相反する機能を制御している．Ang1-Tie2シグナルは内皮細胞間接着によって空間的，機能的に制御されている．細胞間接着を有する内皮細胞において，Ang1はTie2のトランス結合を形成し血管安定化シグナルを活性化する．一方，細胞間接着を持たない内皮細胞では，Ang1はTie2を細胞—基質接着部位にターゲットすることで，血管新生シグナルを惹起する．細胞間接着部位でトランス結合したTie2は，Akt経路を介して，内皮細胞の生存促進作用および抗炎症作用を発揮すると共に，内皮細胞間接着を増強することで，血管構造の安定化に寄与している．血管の不安定化は，様々な疾患の発症と密接に関連しているが ...
Fukuhara, Shigetomo, Mochizuki, Naoki
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