Results 41 to 50 of about 107,707,414 (242)
Cells, 2020 Angiopoietin-1 (Ang-1) is an important proangiogenic factor also involved in the maintenance of endothelial-barrier integrity. The small GTPase Rap1 is involved in the regulation of adherens junctions through VE-cadherin-mediated adhesion, and in ...
Vanda Gaonac’h-Lovejoy +3 more
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Frontiers in Immunology, 2021 Angiogenesis is a critical process in the formation of new capillaries and a key participant in rheumatoid arthritis (RA) pathogenesis. The adipokine apelin (APLN) plays critical roles in several cellular functions, including angiogenesis. We report that
Ting-Kuo Chang +18 more
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Angiopoietin-1 induces sprouting angiogenesis in vitro [PDF]
Current Biology, 1998 Sprouting of new capillaries from pre-existing blood vessels is a hallmark of angiogenesis during embryonic development and solid tumor growth [1]. In addition to the vascular endothelial growth factor (VEGF) and its receptors, the Tie receptors and their newly identified ligands, the angiopoietins, have been implicated in the control of blood vessel ...
Koblizek, TI +4 more
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Journal of Pharmacological Sciences, 2008 Ossification of the posterior longitudinal ligament of the spine (OPLL) is characterized by ectopic ossification in the spinal ligaments, which enlarges with time and compresses the spinal cord, resulting in serious neurological symptoms.
Masaki Kishiya +11 more
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The Role of Angiopoietin-1 in Kidney Disease [PDF]
Electrolyte & Blood Pressure, 2008 Injury to the renal microvasculature and inflammatory process may be major factors in the progression of renal disease, therefore, protection of the renal endothelial cell and regulation of inflammatory process may be an important therapeutic target of renal disease.
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Endothelial Permeability and the Angiopoietin/Tie2 System Following Mild and Severe COVID-19
Artery Research, 2023 Endotheliopathy plays a role in the development of acute kidney and lung injury in COVID-19, probably due to inflammation, endothelial permeability, vascular leakage and edema formation. This study examined alterations in the circulation of patients with
Carolien Volleman +4 more
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Hypertension, Vascular Rarefaction and Angiopoietin-1 [PDF]
Korean Circulation Journal, 2011 Refer to the page 590-595 Hypertension is a very common but incompletely understood disease, especially in its pathogenesis and vascular complications occurring in the cardiovascular research filed. There are many explanations for pathological mechanisms in hypertension, including adrenergic over-reactivity, renin-angiotensin-aldosteron system ...
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Angiopoietin 1 Is Mitogenic for Cultured Endothelial Cells [PDF]
Cancer Research, 2005 Abstract The angiopoietin (Ang)/Tie2 system is implicated in blood vessel formation and maturation. However, the mitogenic effects of angiopoietins remain to be elucidated. Here, we show that Ang1 is mitogenic for cultured endothelial cells.
Shigeru, Kanda +4 more
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Protective Role of Angiopoietin-1 in Endotoxic Shock [PDF]
Circulation, 2005 Background— Angiopoietin-1 (Ang1) plays an essential role in embryonic vasculature development, protects the adult peripheral vasculature from leakage, and has antiinflammatory properties. Because endotoxin-induced shock is a condition with microvascular leakage resulting from inflammation, we ...
Bernhard, Witzenbichler +4 more
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BMC Nephrology, 2020 Background We previously identified two acute kidney injury (AKI) sub-phenotypes (AKI-SP1 and AKI-SP2) with different risk of poor clinical outcomes and response to vasopressor therapy.
Pavan K. Bhatraju +17 more
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