Results 51 to 60 of about 107,707,414 (242)

Increased Angiopoietin-1 and -2 levels in human vitreous are associated with proliferative diabetic retinopathy. [PDF]

PLoS One, 2023
\(\bf Background\) Diabetic retinopathy is a frequent complication of diabetes mellitus and a leading cause of blindness in adults. The objective of this study was to elucidate the diabetic retinopathy pathophysiology in more detail by comparing protein
Tsai T, Alwees M, Asaad MA, Theile J, Kakkassery V, Dick HB, Schultz T, Joachim SC.   +7 more
europepmc   +2 more sources

Down-Regulation of Angiopoietin-1 Expression in Menorrhagia [PDF]

The American Journal of Pathology, 2002
Angiogenesis is an essential component of endometrial repair and regeneration following menses. Perturbation of this process is associated with menorrhagia, a common gynecological disorder that results in excessive menstrual bleeding. Angiopoietin-1 (Ang-1) promotes vascular maturation via the Tie-2 receptor, while angiopoietin-2 (Ang-2) is its natural
Peter, Hewett, Sarbjit, Nijjar, Munjiba, Shams, Susan, Morgan, Janesh, Gupta, Asif, Ahmed   +5 more
openaire   +2 more sources

Evaluation of Angiopoietins 1 and 2 in Malaria-Infested Children [PDF]

Journal of Environmental and Public Health, 2020
Background. Malaria could affect people of all ages, most especially young children. The study evaluated the levels of serum angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2) which are critical regulators of endothelial activation and integrity with some hematological parameters (total white blood cell counts (WBC), total red blood cell counts (RBC ...
A. O. Oluboyo, S. I. Chukwu, B. O. Oluboyo, O. O. Odewusi   +3 more
openaire   +2 more sources

Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis.

, 2011
OBJECTIVE: To determine the utility of angiopoietin-1 and angiopoietin-2 as potentially novel biomarkers of morbidity and mortality in patients with severe sepsis. DESIGN: Multicenter longitudinal cohort study.
Hawkes, Michael, Michael Hawkes, Nimerta Rajwans, W. Conrad Liles, Fox-Robichaud, Alison, Lisa J. Toltl, Alison Fox-Robichaud, Patricia C. Liaw, Cook, Deborah J, Ricciuto, Daniel R, Lafferty, Erin I, Rajwans, Nimerta, Kain, Kevin C, Andrea L. Conroy, Kevin C. Kain, Conroy, Andrea L, Daniel R. Ricciuto, Deborah J. Cook, Kahnamoui, Kamyar, Erin I. Lafferty, dos Santos, Claudia C, Liaw, Patricia C, Liles, W Conrad, Kamyar Kahnamoui, Toltl, Lisa J, Claudia C. dos Santos   +25 more
core   +1 more source

Dexamethasone coordinately regulates angiopoietin-1 and VEGF: A mechanism of glucocorticoid-induced stabilization of blood-brain barrier

, 2021
Glucocorticoids stabilize the blood-brain barrier (BBB), leading to attenuation of vasogenic brain edema. However, the action mechanism of glucocorticoids has been poorly elucidated. To elucidate the mechanism, we investigated whether dexamethasone (Dex),
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core   +1 more source

Angiopoietin-1 for Myocardial Angiogenesis [PDF]

, 2011
In response to ischemic damage, the heart undergoes vicious process of remodeling wherein the damaged myocardium is replaced by scar tissue and as compensatory mechanism, its existing collateral vessels and neovascularization with concomitant changes in cell recruitment, multiplication and cytokine/growth factor action.
Vien Khach, Muhammad Zeeshan, Muhammad Ashraf, Khawaja Husnain   +3 more
openaire   +1 more source

Angiopoietin 1 enhances the proliferation and differentiation of skeletal myoblasts [PDF]

Journal of Cellular Physiology, 2013
AbstractAngiopoietin 1 (Ang1) plays an important role in various endothelial functions, such as vascular integrity and angiogenesis; however, less is known about its function outside of the endothelium. In this study, we examined whether Ang1 has direct effects on skeletal muscle cells.
Lee, Eun Hui, Woo, Jin Seok, Hwang, Ji-Hye, Park, Jae-Hyeong, Cho, Chung-Hyun   +4 more
openaire   +2 more sources

Angiopoietin-2 is associated with albuminuria and microinflammation in chronic kidney disease. [PDF]

PLoS ONE, 2013
Although cardiovascular disease (CVD) is the leading cause of mortality in patients with chronic kidney disease (CKD), the pathophysiology is not thoroughly understood. Given that elevated albuminuria or circulating angiopoietin-2 associates with CVD and
Fan-Chi Chang, Tai-Shuan Lai, Chih-Kang Chiang, Yung-Ming Chen, Ming-Shiou Wu, Tzong-Shinn Chu, Kwan-Dun Wu, Shuei-Liong Lin   +7 more
doaj   +1 more source

Angiopoietin-1 levels and other baseline parameters as predictors of overall mortality/transplant in patients with different PH subtypes.

, 2016
Angiopoietin-1 levels and other baseline parameters as predictors of overall mortality/transplant in patients with different PH subtypes.
Manuel Jonas Richter (2586910), Natascha Sommer (2586913), Ralph Schermuly (3324684), Thomas Schmidt (168952), Henning Gall (759343), Svenja Lena Tiede (3324687), Werner Seeger (5494), Hossein Ardeschir Ghofrani (142879)   +7 more
core   +1 more source

Circulating markers of the endothelial angiopoietin/Tie2 system.

, 2023
Circulating levels of angiopoietin-1 (A), angiopoietin-2 (B), angiopoietin-2/1 ratio (C) and soluble Tie2 (D) in plasma of Tie2+/+ male (white bars), Tie2+/+ female (grey bars), Tie2+/- male (striped white bars) and Tie2+/- female (striped grey bars ...
Anoek L. I. van Leeuwen (8839811), Elise Beijer (17403462), Grietje Molema (64356), Roselique Ibelings (17403465), Matijs van Meurs (358888), Charissa E. van den Brom (3156441), Joris J. T. H. Roelofs (9302018), Nicole A. M. Dekker (10807289), Marjolein R. A. van der Steen (17403468)   +8 more
core   +1 more source