Results 91 to 100 of about 97,507,719 (246)

Circulating serum levels of angiopoietin-1 and angiopoietin-2 in nasopharynx and larynx carcinoma patients

, 2016
We aimed to determine the serum levels of angiogenic factors, namely angiopoietins, in nasopharyngeal and laryngeal carcinoma patients. We also aimed to seek the relation of these molecules with tumor grade and their utility as diagnostic biomarkers.
Serilmez, Murat, Karadeniz, Ahmet, Soydinc, Hilal Oguz, Yasasever, Vildan, Guveli, Murat Emin, Duranyildiz, Derya, Bilgin, Elif   +6 more
core   +1 more source

The ratio of plasma angiopoietin-2 to angiopoietin-1 as a prognostic biomarker in patients with sepsis

Cytokine, 2020
We aimed to investigate the role of angiopoietin (Angpt) as a predictive biomarker for sepsis by evaluating associations between plasma Angpt and various inflammatory cytokines and mortality in critically ill patients with sepsis.This study was a retrospective cohort study of the prospectively collected samples and clinical data of 145 patients with ...
Chang Hwan, Seol, Seung Hyun, Yong, Ju Hye, Shin, Su Hwan, Lee, Ah Young, Leem, Moo Suk, Park, Young Sam, Kim, Kyung Soo, Chung   +7 more
openaire   +3 more sources

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

Phytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source

Imbalance of Angiopoietin-1 and Angiopoetin-2 in Severe Dengue and Relationship with Thrombocytopenia, Endothelial Activation, and Vascular Stability [PDF]

, 2012
Contains fulltext : 108223.pdf (Publisher’s version ) (Open Access)Abstract. The pathogenesis of plasma leakage during dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS) is largely unknown.
Faradz, S.M.H., Djamiatun, K., Michels, M., Fijnheer, R., de Groot, P.G., Ven, A.J.A.M. van der, Griffioen, A.W., Sebastian, S., de Mast, Q.   +8 more
core   +1 more source

Stage-dependent angiopoietin-Tie2 and nitric oxide signaling of erythrocytes in response to surgical trauma in head and neck cancer

World Journal of Surgical Oncology, 2020
Background Angiopoietin-Tie2 and nitric oxide pathway is crucial in tumor angiogenesis and closely correlates with tumor development, growth, and metastasis.
Hsiang-Ling Wu, You-Hsiang Chu, Ying-Hsuan Tai, Mei-Yung Tsou, Cheng-Hsien Wu, Wen-Liang Lo, Shyh-Kuan Tai, Chun-Chang Yeh, Chih-Cherng Lu   +8 more
doaj   +1 more source

Treg‐stromal cell axis in tissue repair and autoimmune diseases: Mechanisms and clinical translation

Rheumatology &Autoimmunity, EarlyView.
The Treg‐stromal cell axis as a central regulator of tissue repair and immune tolerance. Under physiological conditions, bidirectional communication between Tregs and stromal cells—mediated by cell‐surface molecular contacts, anti‐inflammatory cytokines, and extracellular vesicles—orchestrates inflammation resolution, immune tolerance, and complete ...
Peiyan Zhang, Rongyuan Gao, Zhaohui Zheng   +2 more
wiley   +1 more source

Angiopoietin-2 causes pericyte dropout in the normal retina: evidence for involvement in diabetic retinopathy

, 2004
Pericyte loss is an early pathologic feature of diabetic retinopathy, consistently present in retinae of diabetic humans and animals. Because pericyte recruitment and endothelial cell survival are controlled, in part, by the angiopoietin/Tie2 ligand ...
Wagner, P, Breier, G, Renner, O, Feng, Y, Vom Hagen, F, Krzizok, T, Brownlee, M, Hammes, HP, Lin, J, Deutsch, Urban   +9 more
core   +1 more source

Plasma angiopoietin-2 in clinical acute lung injury [PDF]

, 2012
BackgroundAngiopoietin-2 is a proinflammatory mediator of endothelial injury in animal models, and increased plasma angiopoietin-2 levels are associated with poor outcomes in patients with sepsis-associated acute lung injury.
Matthay, Michael A, Abbott, Jason, Gallagher, Diana, Thompson, B Taylor, Calfee, Carolyn S   +4 more
core   +1 more source

Expression of Angiopoietin and VEGF in cervical cancer and its clinical significance

Open Life Sciences, 2018
The aim of this study was to evaluate the expression of Angiopoietin-1 (Ang-1), Angiopoietin-2 (Ang-2) and vascular endothelial growth factor (VEGF) in cervical cancer and its clinical significance.
Lv Qingyuan, Zhong Weijuan, Ye Xiabin, Lv Yang, Liu Haiying, Yan Guizhen, Chen Diwen   +6 more
doaj   +1 more source

ANGPT2 Drives Thyroid Cancer Progression Through PI3K/AKT Signaling and Correlates With Poor Prognosis and Immune Infiltration

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Angiopoietin‐2 (ANGPT2) is known to participate in tumor progression and immune modulation across multiple malignancies. Nevertheless, its expression pattern, prognostic value, and biological function in thyroid cancer (THCA) have not been comprehensively investigated.
Han Chen, Lin Wang, Ji‐Sheng Zhang, Xu‐Dong Yan, Long‐Gang Yu, Yan Jiang   +5 more
wiley   +1 more source