Results 81 to 90 of about 97,507,719 (246)

Optical Coherence Tomography Angiography Flow Signal in Non-Treatment-Naïve Patients with Neovascular Age-Related Macular Degeneration Treated with Faricimab

Medicina
Background and Objectives: Age-related macular degeneration (AMD) remains a leading cause of legal blindness. Anti-Vascular Endothelial Growth Factor (VEGF) agents are the first-line treatment for neovascular AMD (nAMD).
Max Brinkmann, Tom Müller, Marco Köster, Jakob Schweighofer, Mathis Danckwardt, Giuseppe Giannaccare, Paola Marolo, Enrico Borrelli, Michele Reibaldi, Yosuf El-Shabrawi, Mario Damiano Toro   +10 more
doaj   +1 more source

Serum levels of angiopoietin-2 and vascular endothelial growth factor in severe refractory asthma

Egyptian Journal of Chest Disease and Tuberculosis, 2014
Background: Airway and vascular remodeling may play a prominent role in the clinical severity of severe refractory asthma (SRA). Angiopoietin-1 (Ang-1) is an essential mediator of angiogenesis by establishing vascular integrity, whereas angiopoietin-2 ...
Mohamed Hantera, Hamed Abd El-Hafiz, Amira Y. Abdelnaby   +2 more
doaj   +1 more source

Angiogenin, Angiopoietin-1, Angiopoietin-2, and Endostatin Serum Levels in Inflammatory Bowel Disease

, 2011
Background: Angiogenesis is a complex process, involving a great number of mediators. It is implicated in the pathogenesis of numerous diseases, holding a critical role in inflammatory bowel disease (IBD).
Oikonomou, K. A., Andreas N. Kapsoritakis, Tiaka, E. K., Manolakis, A. C., Fotios D. Tsiopoulos, Spiros P. Potamianos, Kapsoritakis, A. N., Kapsoritaki, A. I., Tsiompanidis, I. A., Konstantinos A. Oikonomou, Tsiopoulos, F. D., Potamianos, S. P., Anastasia I. Kapsoritaki, Anastassios C. Manolakis, Elisavet K. Tiaka, Ilias A. Tsiompanidis   +15 more
core   +1 more source

Bisphenol A and Its Analogs: Toxicity Analysis in Mouse and Rat Liver—A Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) and its analogs are widely recognized for their use in industry and plastic manufacturing. Consequently, humans and animals are continually exposed to various substances in their daily lives. This review evaluates the hepatic toxicity of BPA and its analogs in mice and rats, with particular emphasis on molecular mechanisms ...
Sevda Bagdatli, Muhammed Canik, Gizem Gencay, Nurbanu Zengin, Tarık Dinc, Nazan Deniz Yön   +5 more
wiley   +1 more source

Angiopoietin-2: A potential novel diagnostic marker in multiple myeloma

, 2011
Background: Multiple myeloma (MM) was the first hematological malignancy in which a prognostic relevance of bone marrow (BM) angiogenesis was reported.
Rehan Khan, Khan, Rehan, Sharma, Alpana, Suhasini Joshi, Joshi, Suhasini, Sharma, Manoj, Alpana Sharma, Manoj Sharma, Kumar, Lalit, Lalit Kumar   +9 more
core   +1 more source

Expression and Predictive Value of Angiopoietin-2 in Pulmonary Hypertension Associated with Chronic Obstructive Pulmonary Disease

COPD
Clear and effective treatment for pulmonary hypertension (PH) caused by chronic obstructive pulmonary disease (COPD) has not been established, and thus promptly identifying patients with PH is of particular importance.
Ruiqin Ni, Mengrong Xie, Jingying Zhang, Mingmei Zhong   +3 more
doaj   +1 more source

Association between periodontitis and exudative retinal detachment: A population‐based cohort study

Journal of Periodontology, EarlyView.
Abstract Background To investigate whether periodontitis, a common bacterial‐induced inflammatory condition, serves as a risk factor for exudative retinal detachment (ERD), which results from fluid entering the subretinal space due to damage to the retinal pigment epithelium or leaky intraocular vessels, typically associated with inflammatory ...
Earl Fu, Ming‐Ling Tsai, Tsu‐Hsuan Weng, Chi‐Hsiang Chung, Min‐Wen Fu, Wu‐Chien Chien   +5 more
wiley   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.

, 2002
VEGF and Angiopoietin-1 requisitely collaborate during blood vessel development. While Angiopoietin-1 obligately activates its Tie2 receptor, Angiopoietin-2 can activate Tie2 on some cells, while it blocks Tie2 activation on others.
Witte, MH, Witte, C, Campochiaro, PA, Renard, R, Martin, C, Gale, NW, McClain, J, Hackett, SF, Suri, C, Wiegand, SJ, Thurston, G, Yancopoulos, GD, Jackson, D, Wang, Q, Jackson, David   +14 more
core   +1 more source

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source