RAS Inhibitor RMC‐7977 Blocks Vascular Overgrowth of NRASQ61R Mutant Endothelial Cells
ABSTRACT RAS mutations occur in patients with several types of vascular anomalies, but effective treatments remain limited. To address this need, we evaluated the RAS (ON) multi‐selective inhibitor RMC‐7977 in human endothelial cells (ECs) expressing the NRASQ61R mutation found in kaposiform lymphangiomatosis (KLA).
Sara Alharbi +6 more
wiley +1 more source
Randomized phase 2b dose-escalation trial of stem cell therapy with laromestrocel for aging frailty. [PDF]
Ruiz JG +24 more
europepmc +1 more source
Flavonoid-Mediated Suppression of Tumor Angiogenesis: Roles of Ang-Tie/PI3K/AKT. [PDF]
Saini S +8 more
europepmc +1 more source
Dual-mechanism of phytochemicals in cancer therapy: synergistic anti-angiogenic potency in cancer and proangiogenic impact against chemotherapy-induced cytotoxicity in vital organs. [PDF]
Elsayed Abouzed DE +5 more
europepmc +1 more source
Cirrhosis-associated intracranial shunting lesions: illustrative case. [PDF]
Haver J +5 more
europepmc +1 more source
Correction to "Hormone Receptor-Dependent Correlations Between Angiopoietins and VEGF-C in Primary Breast Cancer: Insights Into Lymphangiogenic Biomarkers". [PDF]
europepmc +1 more source
Examining the relationship between vascular biomarkers and both microangiopathy and cutaneous fibrosis in systemic sclerosis. [PDF]
Flower VA +4 more
europepmc +1 more source
Algorithms in Allergy: Hereditary Angioedema
Allergy, Volume 81, Issue 8, Page 3008-3012, August 2026.
Konrad Bork +3 more
wiley +1 more source
Perioperative Blood Biomarkers of Infectious and Non-Infectious Postoperative Pulmonary Complications: A Narrative Review. [PDF]
Gigliotti S +10 more
europepmc +1 more source
Angiogenic Factors and Inflammatory Bowel Diseases. [PDF]
Li Z +5 more
europepmc +1 more source

