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Angiotensin II and Cardiovascular Disease: Balancing Pathogenic and Protective Pathways

The renin-angiotensin-aldosterone system (RAAS) is a hormone system that controls blood pressure and fluid and electrolyte balance. Angiotensin II, a key effector, is produced from angiotensin I by angiotensin-converting enzyme (ACE) and exerts its ...
Ulvi Bayraktutan, Bayraktutan, Ulvi
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Angiotensin-(1-7) Activates Proopiomelanocortin Neurons in the Arcuate Nucleus. [PDF]

Hypertension
Vernail VL, Mehay DL, Kimbark KD, Tanner JA, Bingaman SS, Silberman Y, Arnold AC.   +6 more
europepmc   +1 more source

The Effect of Angiotensin (1-7) on Serum Metabolomics in Obese Type 2 Diabetic Mice. [PDF]

Metabolites
Chen Q, Sun M, Wang H, Lu C.
europepmc   +1 more source

Acute GLP-1 infusion in male adults lowers circulating angiotensin II without changing angiotensinogen, ACE, ACE2, or angiotensin-(1-7) concentrations. [PDF]

Physiol Rep
Asmar A, Akram M, Sorensen CM, Andresen JK, Jensen BL.   +4 more
europepmc   +1 more source

A novel angiotensin(1-7) agonist, PNA5, reduces ischemic reperfusion injury and cardiac dysfunction. [PDF]

Front Cardiovasc Med
Hoyer-Kimura C, Hay M, Methajit M, Polt R, Salcedo V, Fricks JP, Piepho A, Lopez-Pier M, Pier M, Marino VA, Konhilas JP.   +10 more
europepmc   +1 more source

Angiotensin-(1-7) suppresses airway inflammation and airway remodeling via inhibiting ATG5 in allergic asthma. [PDF]

BMC Pulm Med, 2023
Xu J, Yu Z, Liu X.
europepmc   +1 more source

Restoration of the gut barrier integrity and restructuring of the gut microbiome in aging by angiotensin-(1-7). [PDF]

Clin Sci (Lond), 2023
Chittimalli K, Jahan J, Sakamuri A, McAdams ZL, Ericsson AC, Jarajapu YPR.   +5 more
europepmc   +1 more source

Angiotensin-(1-7) Alleviates Isoproterenol-Induced Cardiac Hypertrophy by Suppressing Autophagy and Apoptosis Through the Synergistic Action of Mas Receptor and Angiotensin II Type 2 Receptor. [PDF]

Acta Physiol (Oxf)
Wang X, Guo F, Wang X, Guo Y, Fan S, Hong L, Jin H.   +6 more
europepmc   +1 more source

The role of angiotensin (1-7) in pancreatic β-cell function and survival: A focus on autophagy. [PDF]

Medicine (Baltimore)
Sun MJ, Hu DH, Lu CL.
europepmc   +1 more source

Inhibitory Effect of Trilinolein on Angiotensin Ii-Induced Cardiomyocyte Hypertrophy

, 2009
The myocardial protective effects of trilinolein, isolated from the Chinese herb Sanchi (Panax notoginseng), may be related to its antioxidant effects.
LEE, HORNG-MO;LEE, WEN-SEN;SHIH, NENG- LANG;CHEN, JIN-JER;CHAN, PAUL, 李宏謀;李文森;施能明;陳錦澤;陳保羅   +1 more
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