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Antihypertensive effects of angiotensin-(1-7) [PDF]
Accumulating evidence suggests that angiotensin-(1-7) (Ang-(1-7)) is an important component of the renin-angiotensin system and that the actions of the peptide may either contribute to or oppose those of Ang II.
M.C. Chappell +3 more
doaj +6 more sources
Cardiovascular actions of angiotensin-(1-7) [PDF]
Angiotensin-(1-7) (Ang-(1-7)) is now considered to be a biologically active member of the renin-angiotensin system. The functions of Ang-(1-7) are often opposite to those attributed to the main effector component of the renin-angiotensin system, Ang II ...
Ferreira A.J., Santos R.A.S.
doaj +6 more sources
Angiotensin 1–7 in an experimental septic shock model [PDF]
Background Alterations in the renin–angiotensin system have been implicated in the pathophysiology of septic shock. In particular, angiotensin 1–7 (Ang-(1–7)), an anti-inflammatory heptapeptide, has been hypothesized to have beneficial effects.
Bruno Garcia +12 more
doaj +3 more sources
Angiotensin-(1-7) improves skeletal muscle regeneration [PDF]
Skeletal muscle possesses regenerative potential via satellite cells, compromised in muscular dystrophies leading to fibrosis and fat infiltration. Angiotensin II (Ang-II) is commonly associated with pathological states.
Mayalen Valero-Breton +5 more
doaj +2 more sources
Renal actions of angiotensin-(1-7) [PDF]
The heptapeptide angiotensin-(1-7) is considered to be a biologically active endproduct of the renin-angiotensin system. This angiotensin, which is devoid of the most known actions of angiotensin II such as induction of drinking behavior and ...
A.C. Simões-e-Silva +3 more
doaj +3 more sources
Central angiotensin 1–7 triggers brown fat thermogenesis [PDF]
We tested the hypothesis that third ventricular (3V) injections of angiotensin 1–7 (Ang 1–7) increases thermogenesis in brown adipose tissue (BAT), and whether the Mas receptor mediates this response.
F. S. Evangelista, T. J. Bartness
doaj +2 more sources
Pharmacological Effects of Angiotensin 1–7 on Venous Vascular Tone [PDF]
Background/Objectives: The ACE2/Ang-(1–7)/Mas receptor axis is a protective, counter-regulatory component of the RAAS that opposes Ang II/AT1R-mediated vasoconstriction.
Armond Daci +5 more
doaj +2 more sources
Maternal plasma angiotensin 1-7 concentration is related to twin pregnancy chorionicity in the third trimester of pregnancy [PDF]
IntroductionTwin gestation is related to a higher risk of hypertensive disorders in pregnancy with possible risk stratification depending on chorionicity.
Paweł Pietruski +6 more
doaj +2 more sources
Angiotensin-(1–7) Is a Modulator of the Human Renin-Angiotensin System [PDF]
Abstract—The renin-angiotensin system is important for cardiovascular homeostasis. Currently, therapies for different cardiovascular diseases are based on inhibition of angiotensin-converting enzyme (ACE) or angiotensin II receptor blockade. Inhibition of ACE blocks metabolism of angiotensin-(1–7) to angiotensin-(1–5) and can lead to elevation of ...
Roks, A. J. +6 more
core +5 more sources
The ACE2/Angiotensin-(1–7)/MAS Axis of the Renin-Angiotensin System: Focus on Angiotensin-(1–7) [PDF]
The renin-angiotensin system (RAS) is a key player in the control of the cardiovascular system and hydroelectrolyte balance, with an influence on organs and functions throughout the body. The classical view of this system saw it as a sequence of many enzymatic steps that culminate in the production of a single biologically active metabolite, the ...
Robson Augusto Souza Santos +6 more
openaire +3 more sources

