Results 21 to 30 of about 311,072 (299)
Upregulation of angiotensin-(1-7) formation in human podocytes - enzyme activity assay upon fluid flow shear stress. [PDF]
PLoS ONEThe renin-angiotensin system is known for its role in renal physiology by regulating renal hemodynamics and natriuresis. Overactivation of this system exerts pathological effects in the kidney, primarily mediated by its main effector peptide angiotensin ...
Debora Kaiser-Graf +4 more
doaj +2 more sources
Angiotensin-(1–7) suppresses pyroptosis in cerebral endothelium to decrease blood–brain barrier permeability and cognitive impairments in sepsis [PDF]
Journal of International Medical ResearchObjective This study aimed to explore the influence of the angiotensin-(1–7)/Mas receptor and angiotensin II/angiotensin II type 1 receptor pathways on pyroptosis during sepsis and their subsequent effects on cognitive function.
Yongli Han +7 more
doaj +2 more sources
Angiotensin 1-7 and losartan worsen the cisplatin induced nephrotoxicity in female rats [PDF]
Journal of Nephropharmacology, 2022 Introduction: Cisplatin (CP) is an anti-cancer drug with the most common side effects of nephrotoxicity. Losartan, an angiotensin II type 1 receptor (AT1R) antagonist and angiotensin 1-7 (Ang1-7) protects the kidney against CP administration in males ...
Sayyedehnikta Kasaei +6 more
doaj +1 more source
Pharmaceutics, 2022 The COVID-19 pandemic has put a tremendous stress on the medical community over the last two years. Managing the infection proved a lot more difficult after several research communities started to recognize the long-term effects of this disease.
Minela Aida Maranduca +7 more
doaj +1 more source
Physiological Reports, 2021 Cardiovascular diseases are the principal cause of death worldwide, with hypertension being the most common cardiovascular disease risk factor. High blood pressure (BP) is also associated with an increased risk of poor cognitive performance and dementia ...
Filipe F. Stoyell‐Conti +4 more
doaj +1 more source
Physiological and pathological roles of Ang II and Ang- (1-7) in the female reproductive system
Frontiers in Endocrinology, 2022 The local Renin-Angiotensin System (RAS) has been demonstrated to exist in a wide range of tissues and organs, In the female reproductive system, it is mainly found in the ovary, uterus and placenta.
Yuanyuan Liu +8 more
doaj +1 more source
Journal of Veterinary Internal Medicine, 2021 Background Little is known about the effect of renin angiotensin aldosterone system‐inhibiting (RAASi) drugs on alternative angiotensin peptides (APs) such as angiotensin 1‐7 (Ang1‐7), which are mediated by angiotensin‐converting enzyme 2 (ACE2 ...
Terry Huh +3 more
doaj +1 more source
Pharmaceuticals, 2022 Rheumatoid arthritis (RA) is a chronic inflammatory condition of synovial joints that causes disability and systemic complications. Ang-(1-7), one of the main peptides in the renin-angiotensin (Ang) system (RAS), imposes its protective effects through ...
Sana Khajeh pour +3 more
doaj +1 more source
Angiotensin 1‐7 protects against ventilator‐induced diaphragm dysfunction
Clinical and Translational Science, 2021 Mechanical ventilation (MV) is a life‐saving instrument used to provide ventilatory support for critically ill patients and patients undergoing surgery.
Toshinori Yoshihara +5 more
doaj +1 more source
Metabolism of Angiotensin-(1–7) by Angiotensin-Converting Enzyme [PDF]
Hypertension, 1998 Angiotensin converting enzyme (ACE) inhibitors augment circulating levels of the vasodilator peptide angiotensin-(1–7) [Ang-(1–7)] in man and animals. Increased concentrations of the peptide may contribute to the antihypertensive effects associated with ACE inhibitors.
M C, Chappell +3 more
openaire +2 more sources