Results 111 to 120 of about 131,203 (163)

Development of angiotensin II type 1 receptor antibodies in patients with temporary mechanical circulatory support. [PDF]

open access: yesJHLT Open
Gamero MT   +7 more
europepmc   +1 more source

Angiotensin (1???7) is an antagonist at the type 1 angiotensin II receptor

Journal of Hypertension, 1994
The present study investigated the antagonism of the amino-terminal heptapeptide fragment of angiotensin II ([des-Phe8]-angiotensin II; Ang(1-7)) to angiotensin II (Ang II) both in vitro in rabbit aortae and in vivo in rats.In rabbit isolated endothelium intact aortic rings Ang(1-7) caused a concentration-related rightward displacement of the Ang II ...
J M, Mahon   +3 more
openaire   +2 more sources

Biased Agonism of the Angiotensin II Type 1 Receptor

Mini-Reviews in Medicinal Chemistry, 2012
G protein-coupled receptors (GPCRs) can be activated by multiple ligands and exhibit the capacity to couple to numerous intracellular signal transduction pathways. This property allows GPCRs to be modulated by biased agonists that selectively activate specific subsets of GPCR-regulated cellular signaling proteins.
C M, Godin, S S G, Ferguson
openaire   +2 more sources

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