Results 21 to 30 of about 74,786 (193)

DPP-IV Inhibitor–Associated Angioedema in Patient With Known History of ACE Inhibitor Angioedema

Journal of Investigative Medicine High Impact Case Reports, 2021
The patient is a 69-year-old male with a past medical history of intellectual disability, hypertension, type 2 diabetes mellitus, and angiotensin-converting enzyme (ACE) inhibitor–associated angioedema who presented to the emergency department with ...
Chidinma Ejikeme MD, Chinedu Nwachukwu MD, John Luis Viechweg MD, Ifunanya Ejikeme, Micheal Brescia MD   +4 more
doaj   +1 more source

Low-dose chronic prenatal alcohol exposure abolishes the pro-cognitive effects of angiotensin IV [PDF]

, 2017
Prenatal ethanol exposure (PAE) in humans results in a spectrum of disorders including deficits in learning and memory. Animal models to date have typically used high ethanol doses but have not identified the biochemical changes underlying the cognitive ...
Fidalgo, Sara, Abigail Takyi, Skipper, Charlotte, Sara Fidalgo, Tsiligkaridis, Theodoros, Quadir, Angela, Aisling McIver, Angela Quadir, Takyi, Abigail, Gard, Paul, Charlotte Skipper, Paul R. Gard, Theodoros Tsiligkaridis, McIver, Aisling   +13 more
core   +1 more source

Alternative renin-angiotensin system pathways in adipose tissue and their role in the pathogenesis of obesity

Endocrine Regulations, 2016
Adipose tissue expresses all the renin-angiotensin system (RAS) components that play an important role in the adipogenesis, lipid and glucose metabolism regulation in an auto/paracrine manner.
Slamkova M, Zorad S, Krskova K
doaj   +1 more source

Roles and functions of Atp6ap2 in the brain

Neural Regeneration Research, 2018
The classical renin-angiotensin system (RAS) in the body has been studied intensively in the last decades, since it is known that this system is involved in the regulation of blood pressure.
Alexander Bracke, Oliver von Bohlen und Halbach   +1 more
doaj   +1 more source

A role for the brain RAS in Alzheimer's and Parkinson's diseases

Frontiers in Endocrinology, 2013
The brain renin-angiotensin system (RAS) has available the necessary functional components to produce the active ligands angiotensins II, III, IV, angiotensin (1-7), and angiotensin (3-7).
John William Wright, Leen H Kawas, Joseph W Harding   +2 more
doaj   +1 more source

Physical Frailty and Use of Guideline‐Recommended Drugs in Patients With Heart Failure and Reduced Ejection Fraction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
BACKGROUND Guideline‐recommended therapies that improve prognosis remain underused in clinical practice. Physical frailty may lead to underprescription of life‐saving therapy.
Toru Kondo, Takuji Adachi, Kiyonori Kobayashi, Takahiro Okumura, Hideo Izawa, Toyoaki Murohara, John J. V. McMurray, Sumio Yamada   +7 more
doaj   +1 more source

Protective effects of astragaloside IV against hypertension-induced vascular remodeling involves the DNMT1 and TET2 signaling pathway [PDF]

Archives of Biological Sciences, 2021
Proliferation, migration, and the phenotypic switch of vascular smooth muscle cells (VSMCs) play an important role in vascular remodeling induced by hypertension.
Qin Yingchun, Xie Yilin, Li Aihua, Zhang Xiaoqin, Yan Zhiqiang   +4 more
doaj   +1 more source

Astragaloside IV Attenuated 3,4-Benzopyrene-Induced Abdominal Aortic Aneurysm by Ameliorating Macrophage-Mediated Inflammation

Frontiers in Pharmacology, 2018
Abdominal aortic aneurysm (AAA), characterized by macrophage infiltration-mediated inflammation and oxidative stress, is a potentially fatal disease. Astragaloside IV (AS-IV) has been acknowledged to exhibit antioxidant and anti-inflammatory properties ...
Jiaoni Wang, Yingying Zhou, Shaoze Wu, Kaiyu Huang, Saroj Thapa, Luyuan Tao, Jie Wang, Yigen Shen, Jinsheng Wang, Yangjing Xue, Kangting Ji   +10 more
doaj   +1 more source

Evaluation of metabolically stabilized angiotensin IV analogs as procognitive/antidementia agents [PDF]

, 2013
Angiotensin IV (AngIV: VYIHPF)-related peptides have long been recognized as procognitive agents with potential as antidementia therapeutics. Their development as useful therapeutics, however, has been limited by physiochemical properties that make them ...
Zhu, Mingyan, Wayman, Gary A, Bule-Ghogare, Jyote M, Wright, John W, Appleyard, Suzanne M, Benoist, Caroline C, Kawas, Leen H, McCoy, Alene T, Harding, Joseph W   +8 more
core   +1 more source

Regulation of hemodynamic parameters under conditions of systemic administration of angiotensin II and angiotensin IV to rats after carotid glomectomy

, 2020
Systemic administration of angiotensin II was followed by an increase in systolic BP and HR in rats with carotid glomectomy, the time of attaining maximum values in treated animals was much higher than in sham-operated controls.
Torshin V.I., Pevtsova E.I., Shevchenko L.V., Kotov A.V., Elfimov A.I., Serova O.N.   +5 more
core   +2 more sources