Results 31 to 40 of about 74,786 (193)

Chronic administration of pharmacological doses of angiotensin 1‐7 and iodoangiotensin 1‐7 has minimal effects on blood pressure, heart rate, and cognitive function of spontaneously hypertensive rats

Physiological Reports, 2021
Cardiovascular diseases are the principal cause of death worldwide, with hypertension being the most common cardiovascular disease risk factor. High blood pressure (BP) is also associated with an increased risk of poor cognitive performance and dementia ...
Filipe F. Stoyell‐Conti, Alesa Chabbra, Joseph Puthentharayil, Katya Rigatto, Robert C. Speth   +4 more
doaj   +1 more source

Angiotensin IV improves spatial memory in streptozotocin-induced diabetic rats by reducing oxidative stress and altering BDNF levels [PDF]

, 2021
In this study, we investigated the protective effects of angiotensin IV (Mg IV) on cognitive function in streptozotocin (STZ)-induced diabetic rats. Male Wistar albino rats, were randomly divided into four groups; control (C), diabetes (Dia, 60 mg/kg ...
Sahin, Gulderen, Elibol, Birsen, Gulderen Sahin, Meral, Ismail, Aysu Kilic, Ustunova, Savas, Huri Bulut, Savas Ustunova, Kilic, Aysu, Bulut, Huri, Ismail Meral, Birsen Elibol   +11 more
core   +1 more source

Hypertension regulating angiotensin peptides in the pathobiology of cardiovascular disease

Clinical and Experimental Hypertension, 2018
Renin angiotensin system (RAS) is an endogenous hormone system involved in the control of blood pressure and fluid volume. Dysregulation of RAS has a pathological role in causing cardiovascular diseases through hypertension.
Misbah Hussain, Fazli Rabbi Awan
doaj   +1 more source

The hyperglycemia induced by angiotensin II in rats is mediated by AT1 receptors

Brazilian Journal of Medical and Biological Research, 1998
We have shown that the renin-angiotensin system (RAS) is involved in glucose homeostasis during acute hemorrhage. Since almost all of the physiological actions described for angiotensin II were mediated by AT1 receptors, the present experiments were ...
L.J.C. Machado, U. Marubayashi, A.M. Reis, C.C. Coimbra   +3 more
doaj   +1 more source

Facilitation of Hippocampal Synaptogenesis and Spatial Memory by C-Terminal Truncated Nle¹-Angiotensin IV Analogs [PDF]

, 2011
Angiotensin IV (AngIV; Val(1)-Tyr(2)-Ile(3)-His(4)-Pro(5)-Phe(6))-related peptides have emerged as potential antidementia agents. However, their development as practical therapeutic agents has been impeded by a combination of metabolic instability, poor ...
Zhu, Mingyan, Gary A. Wayman, Wayman, Gary A, Wright, John W, Caroline C. Benoist, Appleyard, Suzanne M, Mingyan Zhu, Benoist, Caroline C, Harding, Joseph W, Joseph W. Harding, John W. Wright, Suzanne M. Appleyard   +11 more
core   +1 more source

Predicted Release and Analysis of Novel ACE-I, Renin, and DPP-IV Inhibitory Peptides from Common Oat (Avena sativa) Protein Hydrolysates Using in Silico Analysis

Foods, 2017
The renin-angiotensin-aldosterone system (RAAS) plays an important role in regulating hypertension by controlling vasoconstriction and intravascular fluid volume. RAAS itself is largely regulated by the actions of renin (EC 3.4.23.15) and the angiotensin-
Stephen Bleakley, Maria Hayes, Nora O’ Shea, Eimear Gallagher, Tomas Lafarga   +4 more
doaj   +1 more source

IRAP and AT₁receptor mediated effects of angiotensin IV [PDF]

Journal of Internal Medicine, 2009
Dupont, A G, Yang, R, Smolders, I, Vanderheyden, P   +3 more
openaire   +3 more sources

Pharmacokinetic characterization of angiotensin IV analogs with therapeutic potential for cancer and dementia

, 2010
Angiotensin IV is a peptide hormone that acts via the AT4 receptor with physiological functions that have not yet been fully elucidated but appear to include important roles in the processes of cognition, fluid balance, blood flow and vascular repair and
McCoy, Alene
core   +2 more sources

Integrated Evaluation of Dual-Functional DPP-IV and ACE Inhibitory Effects of Peptides Derived from Sericin Hydrolysis and Their Stabilities during In Vitro-Simulated Gastrointestinal and Plasmin Digestions

Foods, 2022
Sericin, a byproduct of the silk industry, is an underutilized protein derived from the yellow silk cocoon. This research aimed to produce and characterize the bioactive peptides from sericin using various enzymatic hydrolysis methods.
Papungkorn Sangsawad, Sasikan Katemala, Danou Pao, Saranya Suwanangul, Rachasit Jeencham, Manote Sutheerawattananonda   +5 more
doaj   +1 more source

Classical and Alternative Pathways of the Renin–Angiotensin–Aldosterone System in Regulating Blood Pressure in Hypertension and Obese Adolescents

Biomedicines
Primary hypertension (PH) is the leading form of arterial hypertension (AH) in adolescents. Hypertension is most common in obese patients, where 20 to 40% of the population has elevated blood pressure.
Adrian Martyniak, Dorota Drożdż, Przemysław J. Tomasik   +2 more
doaj   +1 more source