Results 41 to 50 of about 74,786 (193)
Discovery of Inhibitors of Insulin-Regulated Aminopeptidase as Cognitive Enhancers
International Journal of Hypertension, 2012 The hexapeptide angiotensin IV (Ang IV) is a metabolite of angiotensin II (Ang II) and plays a central role in the brain. It was reported more than two decades ago that intracerebroventricular injection of Ang IV improved memory and learning in the rat ...
Hanna Andersson, Mathias Hallberg
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Frontiers in Pharmacology, 2023 Background: Evidence from observational studies concerning the causal role of blood pressure (BP) and antihypertensive medications (AHM) on Parkinson’s disease (PD) remains inconclusive.
Zheng Jiang +19 more
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BMC Gastroenterology, 2002 Background Absorption of water and Na+ in descending colonic crypts is dependent on the barrier function of the surrounding myofibroblastic pericryptal sheath.
Pedley Kevin C +3 more
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Frontiers in Immunology, 2022 The Endoplasmic Reticulum Aminopeptidase 1 and 2 (ERAP1 and ERAP2) and Insulin Regulated Aminopeptidase (IRAP) are three M1 zinc metalloproteases whose role in antigen processing is the refining of peptidome either in the Endoplasmic reticulum (ERAP1 and
Benedetta Mattorre +5 more
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Scientific Reports, 2021 The multifunctional properties of fish gelatin hydrolysates have not been completely elucidated. Here, the biological characterization of these peptides was performed to engineer multifunctional peptides.
Armin Mirzapour-Kouhdasht +4 more
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Brown goat yogurt: Metabolomics, peptidomics, and sensory changes during production
Journal of Dairy Science, 2023 : Brown goat milk products have gained popularity for their unique taste and flavor. The emergence of chain-reversal phenomenon makes the design and development of goat milk products gradually tend to a consumer-oriented model.
R. Zhang, W. Jia
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Comparative studies on angiotensins. IV. Structure of snake (Elaphe climocophora) angiotensin.
Chemical and Pharmaceutical Bulletin, 1977 Three kinds of snake angiotensins have been isolated from the incubation product of snake (Elaphe climocophora) kidney extract with homologous plasma. The amino acid sequences were deduced by dansyl method as follows : Asp-Arg-Val-Tyr-Val-His-Pro-Phe X-Asx-Arg-Val-Tyr-Val-His-Pro-Phe-Tyr X-Asx-Arg-Val-Tyr-Val-His-Pro-Phe-Tyr-Leu Tyrosine in position 9 ...
NAKAYAMA, TAEKO +2 more
openaire +3 more sources
β-Homo-amino Acid Scan of Angiotensin IV
, 2016 Angiotensin IV, a metabolite of angiotensin II, inhibits the enzyme insulin regulated aminopeptidase or IRAP and also, although with lower potency, aminopeptidase-N (AP-N).
Dirk Tourwé (2441938) +9 more
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Brain Sciences, 2021 The renin-angiotensin system (RAS) is a paracrine RAS within the central nervous system (CNS) and is closely related to Alzheimer’s disease (AD). The endogenous hexapeptide angiotensin IV (Ang IV), an important component of the brain RAS, was found to ...
Xiaojin Sun +5 more
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, 2012 [[abstract]]Hemorphins, a family of atypical endogenous opioid peptides, are produced by the cleavage of hemoglobin β-chain. Hemorphins were proved to bind to the μ-opioid receptors (agonist) and angiotensin IV receptors (insulin-regulated aminopeptidase;
Cheng, BC;Tao, PL;Cheng, YY;Huang, EYK
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