Results 51 to 60 of about 1,431 (182)
Circulating Angptl3 and Angptl8 Are Increased in Patients with Hypothyroidism
BioMed Research International, 2019 Purpose. Angiopoietin-like proteins (Angptls) play critical roles in biological processes, primarily in lipid metabolism. The functional state of the thyroid has a profound influence on metabolism in the human body. Therefore, the aim of this study was to investigate possible changes in serum Angptl3, 4, and 8 levels in hypothyroid patients.
Longyan Yang +5 more
openaire +2 more sources
Role of ANGPTL8 in NAFLD Improvement after Bariatric Surgery in Experimental and Human Obesity
, 2021 Angiopoietin-like protein 8 (ANGPTL8) is an hepatokine altered in several metabolic conditions, such as obesity, type 2 diabetes, dyslipidemia and nonalcoholic fatty liver disease (NAFLD).
Victoria Catalán +12 more
core +1 more source
Cardiovascular Diabetology, 2018 Background Hypertriglyceridemia, insulin resistance and hyperglycemia are risk factors for atherosclerosis in type 2 diabetes. Angiopoietin-like protein 8 (ANGPTL8) is a newly identified liver-derived hormone related to these risk factors.
Tianpeng Zheng +6 more
doaj +1 more source
, 2023 Tingxue Zhang,1,2 Yilin Hou,1,2 Min Liu,2 Xiaoyu Hou,1,2 Yong Tang,2 Luping Ren,2 Guangyao Song1,2 1Department of Internal Medicine, Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China; 2Department of Endocrinology, Hebei General ...
Zhang T +6 more
core
Lipids in Health and Disease, 2018 Background Angiopoietin-like protein 8(ANGPTL8) and apolipoprotein CIII (apoCIII) were found to inhibit the activity of lipoprotein lipase (LPL) and disrupt the clearance of triglyceride-rich lipoproteins (TRLs), leading to hypertriglyceridemia.
Mengdie Luo +4 more
doaj +1 more source
Angiopoietin-like 3 inhibition of endothelial lipase is not modulated by angiopoietin-like 8
Journal of Lipid Research, 2021 High plasma triglyceride (TG) levels and low HDL-C levels are risk factors for atherosclerosis and cardiovascular disease. Both plasma TG and HDL-C levels are regulated in part by the circulating inhibitor, angiopoietin-like 3 (ANGPTL3). ANGPTL3 inhibits
Kelli L. Sylvers-Davie +4 more
doaj +1 more source
, 2016 A: Level of full length form of ANGPTL8 in non-obese subjects before and after three months of exercise training. B: Level of C-terminal 139–198 form of ANGPTL8 in non-obese subjects before and after three months of exercise training.
Mohamed Abu-Farha (25322) +6 more
core +1 more source
Lipids in Health and Disease, 2018 Background Angiopoietin-like protein 8 (ANGPTL8) is a novel hormone involved in the regulation of lipid metabolism and glucose homeostasis. There are inconsistent results regarding the association between ANGPTL8 and lipids in humans.
Song Yang +8 more
doaj +1 more source
Angptl8 mediates food-driven resetting of hepatic circadian clock in mice [PDF]
Nature Communications, 2019 AbstractDiurnal light-dark cycle resets the master clock, while timed food intake is another potent synchronizer of peripheral clocks in mammals. As the largest metabolic organ, the liver sensitively responds to the food signals and secretes hepatokines, leading to the robust regulation of metabolic and clock processes.
Siyu Chen +6 more
openaire +3 more sources
Angiopoietin-like protein 8 (betatrophin) may inhibit hepatocellular carcinoma through suppressing of the Wnt signaling pathway [PDF]
Iranian Journal of Basic Medical Sciences, 2019 Objective(s): Hepatocellular carcinoma (HCC) is one of the leading fatal neoplasms and the most common primary liver malignancy worldwide. Peptide hormone ANGPTL8 (betatrophin) may act as an important regulator in HCC development through the Wnt/β ...
Nastaran Monzavi +4 more
doaj +1 more source