Results 91 to 100 of about 10,059 (251)

Performance of Short‐Term Culture and Direct MALDI‐TOF MS for Identification of Candida Species From Blood Cultures

APMIS, Volume 133, Issue 8, August 2025.
ABSTRACT Rapid and reliable identification of Candida spp. is crucial due to changing epidemiology and increasing resistance. This study aims to compare the identification rates, average Log Score (LS) values, and three different methods: short‐term culture, Sepsityper kit, and an in‐house method.
Tugce Unalan‐Altintop, Kristoffer Jansson, Volkan Özenci   +2 more
wiley   +1 more source

In Vitro Antifungal Susceptibility of Clinically Relevant Species Belonging to Aspergillus Section Flavi [PDF]

, 2013
The in vitro antifungal susceptibility of 77 isolates belonging to different clinically relevant species of Aspergillus section Flavi, including those of different phylogenetic clades of A.
Cano, Josep, Colombo, Arnaldo L., Goncalves, Sarah S., Guarro, Josep, Stchigel, Alberto M.   +4 more
core   +2 more sources

Cell wall composition and biofilm formation of azoles-susceptible and -resistant Candida glabrata strains [PDF]

, 2016
In the present study, three strains of Candida glabrata have been investigated to shed light on the mechanisms involved in azole resistance during adherence and biofilm formation.
Angiolella, Letizia, Castagnola, Massimo, Iavarone, Federica, Leone, Claudia, Marzano, Valeria, Vavala, Elisabetta, Vitali, Alberto   +6 more
core   +5 more sources

Synthesis of New Glycometronidazole Compounds With Antifungal and Antifungal Biofilm Activity

Chemical Biology &Drug Design, Volume 106, Issue 2, August 2025.
Novel glyco‐triazole‐metronidazole compounds obtained via a click chemistry reaction—used as antifungal and antifungal biofilm agents. Subsequent antifungal tests showed good results for a number of compounds which are believed to essentially function as a bioactive “Trojan horse.” ABSTRACT Carbohydrates are well known to be one of the most abundant ...
Rayssa de Cassia Alves Iemini, Ana Laura Marques Trinca, Monique Dias Benedetti, Cleydson Finotti Cordeiro, Alessandro Vieira Ferreira, Amanda Latércia Tranches Dias, Ivo Santana Caldas, Jamie Anthony Hawkes, Diogo Teixeira Carvalho, Lucas Lopardi Franco   +9 more
wiley   +1 more source

Criteria for the administration of systemic antimicotic therapy in surgical intensive care units (literature review)

Тазовая хирургия и онкология, 2019
This review focuses on the practical aspects of prevention and treatment of fungal infections in surgical patients. It covers epidemiology and risk factors for invasive candidiasis, updates on the etiological structure of fungal infections in patients in
B. Z. Belotserkovskiy, E. B. Gelfand, A. O. Bykov, O. A. Mamontova, D. N. Protsenko   +4 more
doaj   +1 more source

Effectiveness of an antifungal stewardship programme at a London teaching hospital 2010–16 [PDF]

, 2019
Background The need for antifungal stewardship is gaining recognition with increasing incidence of invasive fungal infection (IFI) and antifungal resistance alongside the high cost of antifungal drugs.
Al-Ghusein, H, Ball, J, Bicanic, T, Glass, S, Houston, A, Klammer, M, Koh, M, Wake, R, Whitney, L, Youngs, J   +9 more
core   +1 more source

Appearance of Environment‐Linked Azole Resistance in the Aspergillus fumigatus Complex in New Zealand

Mycoses, Volume 68, Issue 8, August 2025.
ABSTRACT Background Until 2020, azole resistance in Aspergillus fumigatus complex isolates in New Zealand was due to cyp51A hot spot mutations. This report details the appearance of environment‐linked tandem repeat (TR)‐related azole resistance genotypes since 2021. Methods Isolates were tested by broth micro‐dilution.
Arthur J. Morris, Wendy P. McKinney, Sally A. Roberts, Sasiharan Sithamparanathan, Zain Chaudhry, Matthew C. Fisher   +5 more
wiley   +1 more source

Isolation, identification and characterization of potential impurities of anidulafungin [PDF]

Journal of Pharmaceutical and Biomedical Analysis, 2017
Eight impurities ranging from 0.03 to 0.97% in anidulafungin bulk drug were detected by HPLC. Four impurities (Imp-I, Imp-II, Imp-III and Imp-VIII) among impurities were isolated from the self-prepared or marketed samples of anidulafungin bulk drug by means of preparative HPLC.
Lanning Zhao, Qilong Wang, Yi Bie, Xiaoxia Lu   +3 more
openaire   +3 more sources

Effectiveness and safety of echinocandins combination therapy with the standard of care compared to the standard of care monotherapy for the treatment of invasive aspergillosis infection: a meta-analysis

Frontiers in Pharmacology
BackgroundThis meta-analysis aims to evaluate the effectiveness and safety of combining echinocandins with standard of care (SOC) antifungal drugs for treating invasive aspergillosis infection (IAI).MethodWe searched PubMed, Embase, and Cochrane Library ...
Yazed Saleh Alsowaida, Bader Alshoumr, Shuroug A. Alowais, Khalid Bin Saleh, Alia Alshammari, Kareemah Alshurtan, Haytham A. Wali   +6 more
doaj   +1 more source

Relative Frequency of Paradoxical Growth and Trailing Effect with Caspofungin, Micafungin, Anidulafungin, and the Novel Echinocandin Rezafungin against Candida Species

Journal of Fungi, 2020
Rezafungin is a next-generation echinocandin that has favorable pharmacokinetic properties. We compared the occurrence of paradoxical growth (PG) and trailing effect (TE) characteristics to echinocadins with rezafungin, caspofungin, micafungin and ...
Zoltán Tóth, Lajos Forgács, Tamás Kardos, Renátó Kovács, Jeffrey B. Locke, Gábor Kardos, Fruzsina Nagy, Andrew M. Borman, Awid Adnan, László Majoros   +9 more
doaj   +1 more source