Results 81 to 90 of about 6,869 (208)

Differential in vitro activity of anidulafungin, caspofungin and micafungin against Candida parapsilosis isolates recovered from a burn unit [PDF]

, 2009
Recent studies suggest that differences in antifungal activity among echinocandins may exist. In this study, the activities of three echinocandins (anidulafungin, caspofungin, and micafungin) against Candida parapsilosis isolates from burn unit patients,
Ghannoum, M.A., Vazquez, J.A., Mukherjee, P.K., Golembieski, A., Buhari, M., Chandra, J., Baxa, D., Chen, A.   +7 more
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Susceptibility of the Candida haemulonii Complex to Echinocandins: Focus on Both Planktonic and Biofilm Life Styles and a Literature Review

Journal of Fungi, 2020
Candida haemulonii complex (C. haemulonii, C. duobushaemulonii and C. haemulonii var. vulnera) is well-known for its resistance profile to different available antifungal drugs.
Lívia S. Ramos, Laura N. Silva, Marta H. Branquinha, André L. S. Santos   +3 more
doaj   +1 more source

Antifungal activity and killing kinetics of anidulafungin, caspofungin and amphotericin B against Candida auris

, 2019
DigitalBackground: Candida auris is an emerging MDR pathogen. It shows reduced susceptibility to azole drugs and, in some strains, high amphotericin B MICs have been described. For these reasons, echinocandins were proposed as first-line treatment for C.
Morales López, Soraya, Gamarra, Soledad, Theill, Laura, Macedo, Daiana, Dudiuk, Catiana, Leonardelli, Florencia, Rodríguez, José-Yesid, Berrio, Indira, Salcedo, Soraya, Marín, Adriana, Garcia Effron, Guillermo   +10 more
core   +1 more source

Effect of protein binding on the activity of voriconazole alone or combined with anidulafungin against Aspergillus spp. using a time-kill methodology

, 2012
Objectives: the aims of the study were to explore the activity of total and free (according to protein binding) maximal concentrations achieved in serum after multiple doses of voriconazole 400/200 mg and anidulafungin 200/100 mg against Aspergillus ...
Alou Cervera, Luis, Prieto Prieto, José, Corcuera, María Teresa, Guinea, Jesús, Gómez Aguado, Fernando, González Hidalgo, Natalia, Cafini, Fabio, Sevillano Fernández, David   +7 more
core   +1 more source

Filter Adsorption of Anidulafungin to a Polysulfone-Based Hemofilter During CVVHD In Vitro

, 2017
Candidemia is frequent in critically ill patients, especially in combination with an acute kidney injury (AKI). Echinocandins generally are recommended for therapy of such infections.
Michael Gruber, Bernhard M. Graf, Ittner, Karl-Peter, Gabriel Roth, Peter Kolbinger, Kolbinger, Peter, Karl-Peter Ittner, Gruber, Michael, Roth, Gabriel, Graf, Bernhard M.   +9 more
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Cost-effectiveness analysis of anidulafungin vs fluconazole for the treatment of invasive candidiasis (IC) in Turkey

, 2017
Anidulafungin has been shown to be non-inferior to, and possibly more efficacious, than fluconazole in treating patients with invasive candidiasis (IC). This study aimed to determine the cost-effectiveness of anidulafungin vs fluconazole for treatment of
Turner, Stuart J., Esin Senol, Stuart J. Turner, Chin Fen Neoh, Kong, David C. M., Senol, Esin, Ates Kara, KARA, ATEŞ, David C. M. Kong, DİNLEYİCİ, ENER ÇAĞRI, Ener Cagri Dinleyici, Neoh, Chin Fen   +11 more
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Efficacy of anidulafungin in 539 patients with invasive candidiasis: a patient-level pooled analysis of six clinical trials [PDF]

, 2017
Contains fulltext : 177342.pdf (Publisher’s version ) (Open Access)Objectives: To evaluate the efficacy of anidulafungin for the treatment of candidaemia and invasive candidiasis in a large dataset, including patients with deep-seated ...
José-Artur Paiva, Kullberg, B.J., Yan, J.L., Jean Li Yan, Bart Jan Kullberg, Conte, U., Schlamm, H., Vasquez, J., Herbrecht, R., Paiva, J.A., Aram, J., Garbino, J., Maria Rita Capparella, Marcio Nucci, Swanson, R., Mootsikapun, P., José Vasquez, Piroon Mootsikapun, Jalal Aram, Jorge Garbino, Raoul Herbrecht, Nucci, M., Haran Schlamm, Robert Swanson, Umberto Conte, Capparella, M.R.   +25 more
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Influence of Body Weight Category on Outcomes in Candidemia Patients Treated With Anidulafungin [PDF]

, 2020
BACKGROUND: Case reports and pharmacokinetic data suggest off-label echinocandin dosing may be needed to reach adequate serum concentrations in obese patients. Few outcome studies exist evaluating this population.
Davis, Susan L, Kenney, Rachel M, Hutton, Mary, Vazquez, Jose A   +3 more
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Risk factors of mortality and comparative in-vitro efficacy of anidulafungin, caspofungin, and micafungin for candidemia [PDF]

, 2014
BackgroundAlthough echinocandins have high in vitro antifungal efficacy according to prior reports, comparative studies on the clinical cure rates of anidulafungin, caspofungin, and micafungin in systemic candida infections have not yet been reported ...
See, Lai-Chu, Lee, Chao-Wei, Huang, Shu-Huan, Lee, Sai-Cheong, Chiou, Meng-Jiun, Shih, Hsiang-Ju   +5 more
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Anidulafungin dosing in critically ill patients with continuous venovenous haemodifiltration

Background: Anidulafungin is indicated as a first-line treatment for invasive candidiasis in critically ill patients. In the intensive care unit, sepsis is the main cause of acute renal failure, and treatment with continuous renal replacement therapy ...
Aguilar Aguilar, Gerardo, Badenes-Quiles, Rafael, Belda Nacher, Francisco Javier, Navarro Ortega, David   +3 more
core   +1 more source