Results 61 to 70 of about 6,869 (208)

Functional Implications of Marine Biosurfactants and Their Therapeutic Potential Against Alzheimer's Disease

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Marine‐derived biosurfactants produced by microorganisms (including bacteria, fungi, and yeast) have amphiphilic properties that facilitate membrane interactions and transport across the blood–brain barrier (BBB). These biosurfactants exhibit neuroprotective activity by targeting mechanisms implicated in Alzheimer's disease, including reducing ...
Zainab Irfan, Shakti Ketan Prusty, Sumon Giri, Arijit Nandi, Mostafa Gouda   +4 more
wiley   +1 more source

Epicardial Lead Dysfunction in a Patient With Mechanical Tricuspid Valve—A Challenging Complication

Annals of Noninvasive Electrocardiology, Volume 31, Issue 4, July 2026.
Panel 1: Clinical presentation Patient profile: A 51‐year‐old female with a history of mechanical mitral and tricuspid valve replacements. Clinical condition: Development of complete atrioventricular (AV) block and subsequent epicardial lead dysfunction. Symptoms: Admission with dizziness, syncope, and fatigue.
Tuba Guctekin, Mucahit Yasin Guctekin
wiley   +1 more source

Stability of Anidulafungin in Concentrated Pharmaceutical Solution

, 2017
Background Currently, the reconstitution instructions in the package insert indicate that 100 mg of anidulafungin powder is to be dissolved in 30 ml of sterile water for injection and this reconstituted solution is to be further mixed ...
Siang Fei Yeoh, Chi Lui Ho, Chien Yap, Yin Shan Lim   +3 more
core   +1 more source

Recent Insights into the Paradoxical Effect of Echinocandins

Journal of Fungi, 2017
Echinocandin antifungals represent one of the most important drug classes for the treatment of invasive fungal infections. The mode of action of the echinocandins relies on inhibition of the β-1,3-glucan synthase, an enzyme essentially required for the ...
Johannes Wagener, Veronika Loiko
doaj   +1 more source

Rezafungin Versus Caspofungin in Candidaemia and Invasive Candidiasis: A Post Hoc Pooled Analysis of Phase 2 and Phase 3 Trials

Mycoses, Volume 69, Issue 7, July 2026.
ABSTRACT Background The efficacy and safety of rezafungin in invasive candidiasis (IC) and candidaemia was demonstrated in the Phase 2 STRIVE and Phase 3 ReSTORE trials, and an additional cohort of patients in ReSTORE from China (ReSTORE China). Objectives This post hoc analysis is the first time that combined data from all double‐blind, randomised ...
Alex Soriano, George R. Thompson III, Oliver A. Cornely, Matteo Bassetti, Bart Jan Kullberg, Patrick M. Honoré, Hervé Dupont, Jose A. Vazquez, Haihui Huang, Yingyuan Zhang, Sara Dickerson, Laura Cox, Peter G. Pappas   +12 more
wiley   +1 more source

Pharmakokinetik von Anidulafungin während kontinuierlicher Hämofiltration [PDF]

, 2010
Anidulafungin, ein Echinocandin-Antimykotikum, welches zur neuesten Substanzklasse von Antimykotika gehört, weist ein breites Wirkspektrum gegen Candida-Infektionen und Aspergillosen auf. Der Arzneistoff wird bei schweren systemischen Mykosen eingesetzt.
Stelzer, Christoph
core  

Experience of using anidulafungin for treatment of invasive candidosis in patients after liver transplantation

Трансплантология (Москва), 2016
This article is an example of a successful treatment invasive fungal infections and bacterial infections caused by multidrug-resistant pathogen after liver ...
M. Sh. Khubutiya, N. K. Kuznetsova, S. V. Zhuravel, T. V. Chernenkaya, M. S. Novruzbekov, A. I. Bazhenov, I. I. Goncharova   +6 more
doaj  

An Update on Invasive Fungal Infections in Solid Organ Transplant Recipients

Transplant Infectious Disease, Volume 28, Issue 4, July/August 2026.
ABSTRACT Invasive fungal infections (IFI) remain a significant infection‐related complication in solid organ transplant recipients (SOTRs), the incidence of which has not changed overtime. With a focus on studies and data published after 2019, this narrative review provides an update on the epidemiology and prevention of IFIs in SOTRs and highlights ...
Tina Marinelli, Shahid Husain
wiley   +1 more source

In Vitro Activitiy of Rezafungin in Comparison with Anidulafungin and Caspofungin against Invasive Fungal Isolates (2017 to 2022) in China

Journal of Fungi
The efficacy of different echinocandins is assessed by evaluating the in vitro activity of a novel antifungal, rezafungin, against invasive fungal isolates in comparison with anidulafungin and caspofungin.
Simin Yang, Feifei Wan, Min Zhang, Huiping Lin, Liang Hu, Ziyi Zhou, Dongjiang Wang, Aiping Zhou, Lijun Ni, Jian Guo, Wenjuan Wu   +10 more
doaj   +1 more source

Relative Frequency of Paradoxical Growth and Trailing Effect with Caspofungin, Micafungin, Anidulafungin, and the Novel Echinocandin Rezafungin against Candida Species

Journal of Fungi, 2020
Rezafungin is a next-generation echinocandin that has favorable pharmacokinetic properties. We compared the occurrence of paradoxical growth (PG) and trailing effect (TE) characteristics to echinocadins with rezafungin, caspofungin, micafungin and ...
Zoltán Tóth, Lajos Forgács, Tamás Kardos, Renátó Kovács, Jeffrey B. Locke, Gábor Kardos, Fruzsina Nagy, Andrew M. Borman, Awid Adnan, László Majoros   +9 more
doaj   +1 more source