Results 51 to 60 of about 6,869 (208)

Development of Candidaemia Score (CanDi‐Score) in Decision of Early Empirical Antifungal Treatment for Patients in Intensive Care Unit: The International Prospective Observational ID‐IRI Study

Mycoses, Volume 69, Issue 8, August 2026.
ABSTRACT Background Candidaemia remains a common, life‐threatening infection among intensive care unit (ICU) patients, with high mortality, particularly in patients with delayed diagnosis and treatment. Objectives This international, multicentre, prospective, observational study aimed to identify risk factors for candidaemia in ICU patients and to ...
Bircan Kayaaslan, Halime Araz, Hatice Yağmur Zengin, Rukiyye Bulut, Zeynep Oktay, Meltem Tasbakan, Sumeyra Istek, Elif Doyuk Kartal, Ozlem Bayrak, Ayse Kaya, Fatma Eser, Pınar Yuruk Atasoy, Hatice Esranur Kıratlı, Berfin Cirkin Doruk, Mustafa Uguz, Sema Sarı, Bahar Busra Sivrikaya, Yasemin Akkoyunlu, Lutfiye Nilsun Altunal, Ayse Albayrak, Handan Alay, Gulsen Iskender, Elkholy Amani, Taylan Onder, Dilek Ozcengiz, Mediha Turktan, Mihalj Mirko, Ilad Alavi Darazam, Mohammad Mehdi Shadravan, Reza Yahyavi Sahzabi, Ahmet Cem Yardımcı, Ruveyda Korkmazer, Gunes Senol, Tuba Kuruoglu, Fatih Temocin, Ozlem Alıcı, Meral Sonmezoglu, Aliye Esmaoglu, Zeynep Ture, Andrea Cortegiani, Ozay Akyıldız, Hatice Rahmet Guner, Hakan Erdem   +42 more
wiley   +1 more source

Phenomenon of Dip Effect in Antifungal Susceptibility Testing of Candida tropicalis by using MIC Testing Strips against Echinocandins [PDF]

Journal of Clinical and Diagnostic Research
Minimum Inhibitory Concentration (MIC) of an antifungal is the minimum concentration that completely inhibits the visible growth of fungi under regulated, uniform and consistent in-vitro conditions.
Sujata lall, Vivek Bhat
doaj   +1 more source

In Vitro Killing Activities of Anidulafungin and Micafungin with and without Nikkomycin Z against Four Candida auris Clades

Pharmaceutics, 2023
Candida auris is a multidrug-resistant pathogen against which echinocandins are the drug of choice. However, information on how the chitin synthase inhibitor nikkomycin Z influences the killing activities of echinocandins against C.
Awid Adnan, Andrew M. Borman, Zoltán Tóth, Lajos Forgács, Renátó Kovács, Dávid Balázsi, Bence Balázs, Gergely Udvarhelyi, Gábor Kardos, László Majoros   +9 more
doaj   +1 more source

Central Nervous System Infections in Pediatric Solid Organ Transplant Recipients

Pediatric Transplantation, Volume 30, Issue 8, August 2026.
CNS infections in SOT recipients are rare and presentation can be subtle. Therefore, a low threshold for evaluation is warranted to minimize the associated mortality. ABSTRACT Background Solid organ transplant (SOT) recipients face an increased risk of central nervous system (CNS) infections due to immunosuppression.
Amna AlSaihati, Kathleen E. Hosek, Cristina Otero, Brandon H. Tran, Carrie A. Mohila, David Moreno McNeill, Mini Michael, Krupa R. Mysore, Joseph A. Spinner, Claire E. Bocchini, Kristen G. Valencia Deray   +10 more
wiley   +1 more source

Efficacy and pharmacodynamics of voriconazole combined with anidulafungin in azole resistant invasive aspergillosis. [PDF]

, 2013
Contains fulltext : 118362.pdf (Publisher’s version ) (Open Access)OBJECTIVES: Azole resistance is an emerging problem in the treatment of Aspergillus fumigatus infections.
Melchers, W.J.G., Seyedmousav, S., Mouton †, J.W., Mouton, J.W., Bruggemann, R.J.M., Verweij, P.E.   +5 more
core   +1 more source

Activity of anidulafungin against Candida albicans isolated from clinical specimens

Current Issues in Pharmacy and Medical Sciences, 2009
Infections caused by C. albicans are an important medical problem in people from risk groups, e.g. hospitalized patients. The aim of this paper was to analyse by the E-test procedure, the in vitro activity of anidulafungin against clinical isolates of C.
Anna Biernasiuk, Katarzyna Matuska, Agnieszka Grzegorczyk, Justyna Szymańska, Anna Malm   +4 more
doaj  

Pharmacokinetics of echinocandins in suspected candida peritonitis: A potential risk for resistance

International Journal of Infectious Diseases, 2020
Introduction: A possible increase in Candida resistance, especially in Candida glabrata, has been speculated according to poor diffusion of echinocandins to peritoneal fluid.
Francesca Gioia, Alicia Gomez-Lopez, Maria Elena Alvarez, Elia Gomez-García de la Pedrosa, Pilar Martín-Davila, Manuel Cuenca-Estrella, Santiago Moreno, Jesús Fortun   +7 more
doaj   +1 more source

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

Advanced Science, Volume 13, Issue 41, 22 July 2026.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li   +8 more
wiley   +1 more source

Filter Adsorption of Anidulafungin to a Polysulfone-Based Hemofilter During CVVHD In Vitro [PDF]

, 2018
Candidemia is frequent in critically ill patients, especially in combination with an acute kidney injury (AKI). Echinocandins generally are recommended for therapy of such infections.
Kolbinger, Peter
core   +1 more source

Combination Antifungal Therapy and Formulary Optimization for Progressive Invasive Pulmonary Aspergillosis in a Pediatric Patient With Acute Myeloid Leukemia: A Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Therapeutic response in refractory invasive pulmonary aspergillosis may depend not only on antifungal class escalation, but also on formulation choice. In this complex pediatric acute myeloid leukemia (AML) case, radiologic improvement followed combination therapy and switch to brand‐name liposomal amphotericin B, underscoring the importance ...
Faryal Khamis, Amal Al Busaidi, Kawther Al Bahrani, Asia Al‐Rashdi   +3 more
wiley   +1 more source