Results 51 to 60 of about 9,092 (211)

An Update on Invasive Fungal Infections in Solid Organ Transplant Recipients

Transplant Infectious Disease, EarlyView.
ABSTRACT Invasive fungal infections (IFI) remain a significant infection‐related complication in solid organ transplant recipients (SOTRs), the incidence of which has not changed overtime. With a focus on studies and data published after 2019, this narrative review provides an update on the epidemiology and prevention of IFIs in SOTRs and highlights ...
Tina Marinelli, Shahid Husain
wiley   +1 more source

Prescribing patterns of echinocandins in adult patients in a private hospital in Gauteng, South Africa

Southern African Journal of Infectious Diseases, 2023
Background: Worldwide, the leading cause of invasive candidiasis and the fourth leading cause of hospital-acquired infections are the Candida species (spp.) group.
Anja Grey, Rianda Joubert, Stephan Steyn, Marlene Julyan   +3 more
doaj   +1 more source

Integrated Genomic and Phenotypic Analyses Reveal Convergent Resistance Patterns in Clinical Candida tropicalis Isolates

Mycoses, Volume 69, Issue 5, May 2026.
ABSTRACT Background The incidence of Candida tropicalis isolation is increasing in hospital settings. High azole resistance and mortality rates make it a pathogen that requires further analysis. Methods Fourteen azole resistant Candida glabrata clinical isolates were collected from a Lebanese hospital and analysed through whole genome sequencing for ...
Christy Chedraoui, Nour Fattouh, Setrida El Hachem, Tsolaire Sourenian, Louna El Bitar, Lama El Moheb, Anna‐Souraya Sleiman, Ibrahim Bitar, Rola Husni, Roy A. Khalaf   +9 more
wiley   +1 more source

Caspofungin versus anidulafungin in patients with invasive candidiasis: a retrospective study with propensity-score-matched analysis

Therapeutic Advances in Infectious Disease
Background: Echinocandins are recommended as an initial treatment for invasive candidiasis. Although safety and efficacy profiles of both anidulafungin and caspofungin are well established, direct head-to-head comparisons have not been reported before ...
Reem Hasan Elajez, Dana Bakdach, Sara Al Balushi, Ahmed Zaqout, Rand Alattar, Tasneem Abdallah, Waleed Awouda, Godwin Wilson, Walid Al-Wali, Emad Ibrahim, Hussam Alsoub   +10 more
doaj   +1 more source

Pharmacokinetics of echinocandins in suspected candida peritonitis: A potential risk for resistance

International Journal of Infectious Diseases, 2020
Introduction: A possible increase in Candida resistance, especially in Candida glabrata, has been speculated according to poor diffusion of echinocandins to peritoneal fluid.
Francesca Gioia, Alicia Gomez-Lopez, Maria Elena Alvarez, Elia Gomez-García de la Pedrosa, Pilar Martín-Davila, Manuel Cuenca-Estrella, Santiago Moreno, Jesús Fortun   +7 more
doaj   +1 more source

Can Intravenous Antifungal therapy be safely used in the Outpatient Parenteral Antimicrobial Therapy (OPAT) setting? [PDF]

, 2019
Outpatient parenteral antimicrobial therapy (OPAT) is an established treatment option for patients with a variety of infections who require a period of intravenous therapy, are clinically stable, and do not require continuous monitoring.
Kenny, Claire, Muldoon, Eavan G., Rae, Nikolas   +2 more
core   +2 more sources

Immunocompromised Status Definition in Observational Studies Using Electronic Health Records: A Scoping Review and a Proposal for a Phenotype Identification Algorithm

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 4, April 2026.
ABSTRACT Immunocompromised individuals experience an impaired immune function due to conditions that might be either congenital or acquired over the course of their lives. Epidemiological studies often rely on clinical definitions which, in some cases, benefit from being translated into machine‐readable algorithms for application to electronic health ...
Judit Riera‐Arnau, Nicoletta Luxi, Fabio Riefolo, Martín Solorzano, Irene Pazos, Elena Ballarín, Lise Skovgaard Svingel, Lorenzo Chiusaroli, Elisa Martín‐Merino, Elisa Barbieri, María Lopez‐Lasanta, Sima Mohammadi, Denis Rotta, Alexandra Pacurariu, Catherine Cohet, Miriam Sturkenboom, Carlos E. Durán, on behalf of the SAFETY‐VAC study consortium, Carlos E. Durán, Miriam Sturkenboom, Judit Riera‐Arnau, Nicoletta Luxi, Olaf Klungel, Patrick Souverein, Sima Mohammadi, Fabio Riefolo, Irene Pazos, Rosa Gini, Davide Messina, Giuseppe Roberto, Carlo Giaquinto, Elisa Barbieri, Luca Stona, Felipe Villalobos, Martín Solorzano, Carlo Alberto Bissacco, Antonio Gimeno, Beatriz Poblador, Mercedes Aza, Aida Moreno, Alejandro Santos, Vera Ehrenstein, Lise Skovgaard Svingel, Benjamin Randeris Johannesen, Cécile Droz‐Perroteau, Laure Carcaillon‐Bentata, Anna‐Mija Tolppanen, Sirpa Hartikainen, Thuan Vo, Anne Paakinaho, Blair Rajamaki, Hedvig Nordeng, Saeed Hayati, Mahmoud Zidan, Juan José Carreras Martínez, Arantxa Urchueguía Fornes, Elisa Correcher Martínez, Javier Díez‐Domingo, Mar Martin, Patricia Garcia‐Poza, Airam de Burgos, Belén Castillo‐Cano, Elisa Martín‐Merino   +62 more
wiley   +1 more source

In Vitro Killing Activities of Anidulafungin and Micafungin with and without Nikkomycin Z against Four Candida auris Clades

Pharmaceutics, 2023
Candida auris is a multidrug-resistant pathogen against which echinocandins are the drug of choice. However, information on how the chitin synthase inhibitor nikkomycin Z influences the killing activities of echinocandins against C.
Awid Adnan, Andrew M. Borman, Zoltán Tóth, Lajos Forgács, Renátó Kovács, Dávid Balázsi, Bence Balázs, Gergely Udvarhelyi, Gábor Kardos, László Majoros   +9 more
doaj   +1 more source

Susceptibility of Candida glabrata biofilms to echinocandins: alterations in the matrix composition [PDF]

, 2018
Candidiases are the most recurrent fungal infections, especially among immunosuppressed patients. Although Candida albicans is still the most widespread isolated species, non-Candida albicans Candida species have been increasing.
Arendrup MC, Célia F. Rodrigues, De Luca C, Grandesso S, Jabra-rizk MA, Maria Elisa Rodrigues, Mariana Henriques, Pappas PG, Pfaller MA, Williams DW   +9 more
core   +1 more source

The Epidemiology and Infection Control of Candida Auris in Shanghai

Mycoses, Volume 69, Issue 4, April 2026.
ABSTRACT Background Candida auris is a globally emerging multidrug‐resistant fungus. Its dissemination is driven by patient movement and asymptomatic carriers. However, molecular epidemiological studies linking imported cases to local strains in large metropolitan areas remain limited.
Mingjing Wei, Jian Guo, Li Li, Junhao Zhu, Yuyuan Xue, Guo Chen, Fan Yang, Wenjuan Wu, Min Zhu   +8 more
wiley   +1 more source