Results 31 to 40 of about 6,464 (211)

In Vitro Interaction and Killing-Kinetics of Amphotericin B Combined with Anidulafungin or Caspofungin against Candida auris

Pharmaceutics, 2021
Treatment of invasive infections caused by Candida auris is challenging due to the limited therapeutic options. The combination of antifungal drugs may be an interesting and feasible approach to be investigated.
Unai Caballero, Elena Eraso, Guillermo Quindós, Nerea Jauregizar   +3 more
doaj   +1 more source

Are anidulafungin or voriconazole released from polymethylmethacrylate in vitro? [PDF]

, 2011
Depot delivery of antimicrobial agents is used for treatment and prevention of bacterial orthopaedic infections; there is little information regarding newer antifungal agents and their potential use in polymethylmethacrylate (PMMA) depot delivery.
Robin Patel, Andras Heijink, Heijink, Andras, Steckelberg, James M., Rouse, Mark S., Patel, Robin, Mark S. Rouse, James M. Steckelberg   +7 more
core   +1 more source

Are We Ready for Nosocomial Candida auris Infections? Rapid Identification and Antifungal Resistance Detection Using MALDI-TOF Mass Spectrometry May Be the Answer

Frontiers in Cellular and Infection Microbiology, 2021
The occurrence of multidrug-resistant Candida auris isolates and the increased mortality associated with invasive infections or outbreaks due to this Candida species have been reported in many healthcare settings.
Elena De Carolis, Federica Marchionni, Marilisa La Rosa, Jacques F. Meis, Jacques F. Meis, Anuradha Chowdhary, Brunella Posteraro, Maurizio Sanguinetti, Maurizio Sanguinetti   +8 more
doaj   +1 more source

Parallel and cross-resistances of clinical yeast isolates determined by susceptibility pattern analysis

GMS Infectious Diseases, 2016
For calculated initial antifungal therapy, knowledge on parallel and cross-resistances are vitally important particularly in the case of multiresistant isolates.
Schmalreck, Arno F., Willinger, Birgit, Idelevich, Evgeny A., Fegeler, Christian, Lass-Flörl, Cornelia, Fegeler, Wolfgang, Becker, Karsten   +6 more
doaj   +1 more source

Stability of Anidulafungin in Concentrated Pharmaceutical Solution [PDF]

, 2017
Background Currently, the reconstitution instructions in the package insert indicate that 100 mg of anidulafungin powder is to be dissolved in 30 ml of sterile water for injection and this reconstituted solution is to be further mixed ...
Siang Fei Yeoh, Chi Lui Ho, Chien Yap, Yin Shan Lim   +3 more
core   +1 more source

Comparison of In Vitro Killing Activity of Rezafungin, Anidulafungin, Caspofungin, and Micafungin against Four Candida auris Clades in RPMI-1640 in the Absence and Presence of Human Serum

Microorganisms, 2021
Candida auris is an emerging and frequently multidrug-resistant pathogen against which the echinocandins are the preferred therapeutic option. We compared killing activities of anidulafungin, caspofungin, micafungin, and rezafungin against 13 isolates ...
Renátó Kovács, Zoltán Tóth, Jeffrey B. Locke, Lajos Forgács, Gábor Kardos, Fruzsina Nagy, Andrew M. Borman, László Majoros   +7 more
doaj   +1 more source

Limited-sampling strategies for anidulafungin in critically ill patients [PDF]

, 2015
Efficacy of anidulafungin is driven by the area under the concentration-time curve (AUC)/MIC ratio. Determination of the anidulafungin AUC along with MIC values can therefore be useful.
Kosterink, Jos G.W., Alffenaar, Jan-Willem C., Kosterink, Jos G.W.; id_orcid, Zijlstra, Jan G.; id_orcid, van der Werf, Tjip S., Zijlstra, Jan G., Uges, Donald R.A., Proost, Johannes H., van Wanrooy, Marjolijn J.P., Rodgers, Michael G. G.   +9 more
core   +1 more source

Successfully treated bilateral renal fungal balls with continuous Anidulafulgin irrigation

Urology Case Reports, 2021
A 73-year-old man with a history of type 2 diabetes mellitus, nephrolithiasis, and recurrent urinary tract infections caused by Candida glabrata was admitted to our hospital. Urosepsis was diagnosed and C.
N.A.M. van Merode, J.J. Pat, M.J.H.M. Wolfhagen, G.A. Dijkstra   +3 more
doaj   +1 more source

Multiple-dose pharmacokinetics of anidulafungin during continuous venovenous haemofiltration [PDF]

, 2011
Background: Clinical studies support a role for anidulafungin as first-line treatment of invasive candidiasis in critically ill patients and postulate no need for dose adjustments in mild to severe renal failure.
Meyer, Brigitte (Medizinische Universität Wien), Thalhammer, Florian (Universitätsklinik für Innere Medizin I), Böhmdorfer, Michaela (University of Vienna), Zuba, Clara (Medizinische Universität Wien), Fuhrmann, Valentin (University of Vienna), Jäger, Walter (University of Vienna), Leitner, Judith M. (Medizinische Universität Wien), Saria, Katrin (Medizinische Universität Wien)   +7 more
core   +1 more source

Echinocandin Drugs Induce Differential Effects in Cytokinesis Progression and Cell Integrity

Pharmaceuticals, 2021
Fission yeast contains three essential β(1,3)-D-glucan synthases (GSs), Bgs1, Bgs3, and Bgs4, with non-overlapping roles in cell integrity and morphogenesis.
Natalia Yagüe, Laura Gómez-Delgado, M. Ángeles Curto, Vanessa S. D. Carvalho, M. Belén Moreno, Pilar Pérez, Juan Carlos Ribas, Juan Carlos G. Cortés   +7 more
doaj   +1 more source