Results 21 to 30 of about 6,415 (210)

Anidulafungin and its role in candida infections

Infection and Drug Resistance, 2009
Diane M Cappelletty, Rose JungThe University of Toledo, College of Pharmacy, Toledo, OH, USAAbstract: Candida infections continue to play a significant role not only in critically ill and immunocompromised patients but also in non-compromised patients ...
Diane M Cappelletty, Rose Jung
doaj   +1 more source

Prevalence Rates, Species Distribution and Antifungal Susceptibility of Rare Candida and Related Saccharomycotina Yeasts Causing Bloodstream Infections in 28 Medical Centres. [PDF]

Mycoses
ABSTRACT Background There is a lack of contemporary studies addressing the prevalence rates and antifungal susceptibility of bloodstream infections (BSI) caused by rare yeasts (RY) from the Saccharomycotina subphylum. Objectives This 16‐year multicentre study (2007–2023) aimed to assess the prevalence and antifungal susceptibility of rare yeasts ...
Buonafine CP, Dos Santos AE, Favarello LM, Cognialli RCR, Aquino VR, Mendes AVA, Guimarães T, Sukiennik TCT, Carlesse F, Castro PTOE, Vicente VA, Francisco EC, Colombo AL.   +12 more
europepmc   +2 more sources

A New Antifungal-Loaded Sol-Gel Can Prevent Candida albicans Prosthetic Joint Infection

Antibiotics, 2021
Fungal PJI is one of the most feared complications after arthroplasty. Although a rare finding, its high associated morbidity and mortality makes it an important object of study. The most frequent species causing fungal PJI is C. albicans. New technology
Hugo Garlito-Díaz, Jaime Esteban, Aranzazu Mediero, Rafael Alfredo Carias-Cálix, Beatriz Toirac, Francisca Mulero, Víctor Faus-Rodrigo, Antonia Jiménez-Morales, Emilio Calvo, John Jairo Aguilera-Correa   +9 more
doaj   +1 more source

In Vitro Susceptibilities of Worldwide Isolates of Intrapulmonary Aspergillus Species and Important Candida Species in Sterile Body Sites against Important Antifungals: Data from the Antimicrobial Testing Leadership and Surveillance Program, 2017–2020

Microbiology Spectrum, 2022
To understand the changes of resistance in clinically commonly encountered fungi, we used the Antimicrobial Testing Leadership and Surveillance (ATLAS) database to explore in vitro antifungal susceptibilities against clinically important isolates of ...
Shio-Shin Jean, Hung-Jen Yang, Po-Chuen Hsieh, Yu-Tsung Huang, Wen-Chien Ko, Po-Ren Hsueh   +5 more
doaj   +1 more source

Post-antifungal effect of the combination of anidulafungin with amphotericin B and fluconazole against fluconazolesusceptible and -resistant Candida albicans [PDF]

Current Medical Mycology, 2022
Background and Purpose: Invasive candidiasis is a life-threatening condition that kills a large number of immunocompromised patients each year worldwide.
narges aslani, Narges Vaseghi, Majid Piramoon, shaghayegh khojasteh, Kiana Abbasi, sahar mohseni, Javad Javidnia, Behrooz Naghili   +7 more
doaj   +1 more source

Pan-Echinocandin Resistant C. parapsilosis Harboring an F652S Fks1 Alteration in a Patient with Prolonged Echinocandin Therapy

Journal of Fungi, 2022
The isolation of a pan-echinocandin-resistant Candida parapsilosis strain (anidulafungin, caspofungin, micafungin and rezafungin EUCAST MICs > 8 mg/L) from urine of a patient following prolonged exposure to echinocandins (38 days of micafungin followed ...
Maria Siopi, Antonios Papadopoulos, Anastasia Spiliopoulou, Fotini Paliogianni, Nissrine Abou-Chakra, Maiken Cavling Arendrup, Christina Damoulari, Georgios Tsioulos, Efthymia Giannitsioti, Frantzeska Frantzeskaki, Iraklis Tsangaris, Spyros Pournaras, Joseph Meletiadis   +12 more
doaj   +1 more source

Candidemia in cancer patients: phenotypical and molecular-genetic characteristics of antifungal drug resistance, pathogenic factor genes of Candida spp.

Сибирский онкологический журнал, 2022
Relevance. The global trend of rapid increase in resistance to antifungal drugs due to multiple factors, dictates the need for continuous monitoring of taxonomic structure and susceptibility of nosocomial pathogens, causing invasive fungal infections ...
N. S. Bagirova, E. A. Goremykina, P. V. Slukin, O. E. Khokhlova, N. K. Fursova, I. N. Petukhova, Z. V. Grigorievskaya   +6 more
doaj   +1 more source

Invasive candidiasis in children

Журнал инфектологии, 2021
The prevalence of invasive candidiasis (IC) in pediatric hospitals is from 4,3 to 15,2 per 10,000 hospitalized, in ICU – from 3,5 to 7 cases per 1,000, with HSCT – 2,9%. The average length of stay of a patient in the hospital before the development of IC
N. N. Klimko, O. P. Kozlova
doaj   +1 more source

Evaluation of the in vitro Activity and in vivo Efficacy of Anidulafungin-Loaded Human Serum Albumin Nanoparticles Against Candida albicans

Frontiers in Microbiology, 2021
Recent decades have seen a significant increase in invasive fungal infections, resulting in unacceptably high mortality rates. Anidulafungin (AN) is the newest echinocandin and appears to have several advantages over existing antifungals.
Yu Zhang, Yan-Chao Liu, Yan-Chao Liu, Si-Min Chen, Hui Zong, Wei-Tong Hou, Xi-Ran Qiu, Shi-Yu Guo, Yu-Fang Sun, Yuan-Ying Jiang, Mao-Mao An, Hui Shen   +11 more
doaj   +1 more source

In vitro synergy of echinocandins with triazoles against fluconazole-resistant Candida parapsilosis complex isolates

Journal of Global Antimicrobial Resistance, 2020
Introduction: Candida parapsilosis (C. parapsilosis) is a common non-albicans Candida species ranked as the second common cause of bloodstream infections. Azole resistance and elevated echinocandin MICs have been reported for these fungi.
Ali Ahmadi, Shahram Mahmoudi, Sassan Rezaie, Sayed Jamal Hashemi, Eric Dannaoui, Hamid Badali, Mansoureh Ghaffari, Farzad Aala, Alireza Izadi, Aida Maleki, Jacques F. Meis, Sadegh Khodavaisy   +11 more
doaj   +1 more source