Results 21 to 30 of about 9,092 (211)

Retrospective cohort study comparing the risk of severe hepatotoxicity in hospitalized patients treated with echinocandins for invasive candidiasis in the presence of confounding by indication

BMC Infectious Diseases, 2018
Background To compare the risk of severe hepatotoxicity with anidulafungin versus caspofungin and micafungin in hospitalized adults. Methods This retrospective cohort study combined data from two large US- based hospital electronic medical record ...
Francis Vekeman, Lisa Weiss, Jalal Aram, Raluca Ionescu-Ittu, Shahrzad Moosavi, Yongling Xiao, Wendy Y. Cheng, Rachel H. Bhak, Margaret Tawadrous, M. Rita Capparella, Philippe Montravers, Mei Sheng Duh   +11 more
doaj   +1 more source

In Vitro Interaction and Killing-Kinetics of Amphotericin B Combined with Anidulafungin or Caspofungin against Candida auris

Pharmaceutics, 2021
Treatment of invasive infections caused by Candida auris is challenging due to the limited therapeutic options. The combination of antifungal drugs may be an interesting and feasible approach to be investigated.
Unai Caballero, Elena Eraso, Guillermo Quindós, Nerea Jauregizar   +3 more
doaj   +1 more source

Two cases of fungal keratitis caused by Metarhizium anisopliae [PDF]

, 2018
We present two cases of keratitis due to Metarhizium anisopliae in geographically separated areas of the United States. The isolates were microscopically similar but morphologically different and were identified by ribosomal DNA sequencing. Both isolates
Burd, Eileen M, Burnham, Carey-Ann D, Goodman, Abigail L, Lockhart, Shawn R, Lysen, Colleen B, Westblade, Lars F   +5 more
core   +2 more sources

Potential Use of MALDI-ToF Mass Spectrometry for Rapid Detection of Antifungal Resistance in the Human Pathogen Candida glabrata. [PDF]

, 2017
The echinocandins are relatively new antifungal drugs that represent, together with the older azoles, the recommended and/or preferred agents to treat candidaemia and other forms of invasive candidiasis in human patients.
De Carolis, E., Mello, E., Perlin, D.S., Posteraro, B., Sanglard, D., Sanguinetti, M., Vella, A.   +6 more
core   +2 more sources

Efficacy of liposomal amphotericin B and anidulafungin using an antifungal lock technique (ALT) for catheter-related Candida albicans and Candida glabrata infections in an experimental model.

PLoS ONE, 2019
ObjectiveThe aims of this study were as follows. First, we sought to compare the in vitro susceptibility of liposomal amphotericin B (LAmB) and anidulafungin on Candida albicans and Candida glabrata biofilms growing on silicone discs.
Jana Basas, Marta Palau, Xavier Gomis, Benito Almirante, Joan Gavaldà   +4 more
doaj   +1 more source

Parallel and cross-resistances of clinical yeast isolates determined by susceptibility pattern analysis

GMS Infectious Diseases, 2016
For calculated initial antifungal therapy, knowledge on parallel and cross-resistances are vitally important particularly in the case of multiresistant isolates.
Schmalreck, Arno F., Willinger, Birgit, Idelevich, Evgeny A., Fegeler, Christian, Lass-Flörl, Cornelia, Fegeler, Wolfgang, Becker, Karsten   +6 more
doaj   +1 more source

Are We Ready for Nosocomial Candida auris Infections? Rapid Identification and Antifungal Resistance Detection Using MALDI-TOF Mass Spectrometry May Be the Answer

Frontiers in Cellular and Infection Microbiology, 2021
The occurrence of multidrug-resistant Candida auris isolates and the increased mortality associated with invasive infections or outbreaks due to this Candida species have been reported in many healthcare settings.
Elena De Carolis, Federica Marchionni, Marilisa La Rosa, Jacques F. Meis, Jacques F. Meis, Anuradha Chowdhary, Brunella Posteraro, Maurizio Sanguinetti, Maurizio Sanguinetti   +8 more
doaj   +1 more source

Time-Kill Kinetics and In Vitro Antifungal Susceptibility of Non-fumigatus Aspergillus Species Isolated from Patients with Ocular Mycoses [PDF]

, 2015
Aspergillus species can cause ocular morbidity and blindness, and thus, appropriate antifungal therapy is needed. We investigated the in vitro activity of itraconazole, voriconazole, posaconazole, caspofungin, anidulafungin, and amphotericin B against 14
Gökbolat, E. (Egemen), Ilkit, M., Kiraz, N. (Nuri), Ozdemir, H.G. (Havva Gül), Seyedmousavi, S. (Seyedmojtaba), Öz, Y. (Yasemin)   +5 more
core   +7 more sources

Multidrug-resistant Candida glabrata strains obtained by induction of anidulafungin resistance in planktonic and biofilm cells

Brazilian Journal of Pharmaceutical Sciences, 2019
Candida glabrata has emerged as a common cause of serious life-threatening fungal infections, largely owing to their low susceptibility to azole antifungals. Recent guidance indicates the use of echinocandins as the first-choice drug for the treatment of
Camila Hatwig, Eduardo A. Balbueno, Vanessa Z. Bergamo, Bruna Pippi, Alexandre M. Fuentefria, Gustavo P. Silveira   +5 more
doaj   +1 more source

Comparing the results of invasive candidiasis prevention with anidulafungin vs. the lipid formulation of amphotericin B in high-risk patients in the early postoperative period after liver transplantation

Трансплантология (Москва), 2020
Introduction. The development of invasive candidiasis leads to high mortality after liver transplantation. Choosing an effective prophylaxis is an important task.The study purpose was to compare the results  of invasive candidiasis prevention with ...
S. V. Zhuravel, N. K. Kuznetsova, I. I. Utkina, M. S. Novruzbekov, P. V. Gavrilov, T. V. Chernenkaya, G. K. Ospanova   +6 more
doaj   +1 more source